purM
mL2205c
PROBABLE PHOSPHORIBOSYLFORMYLGLYCINAMIDINE CYCLO-LIGASE PURM (AIRS) (PHOSPHORIBOSYL-AMINOIMIDAZOLE SYNTHETASE) (AIR SYNTHASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2619428 – 2620522
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2205c_purM_dna
TATCGCGATGATGGATCCCGGAAAAAGCCCCGGAGGCCAGCTGGGCAATCATGGCATCACCTATGCGTCGACAGGGGTGGACATTGAAGCCGGTGACCGCTCGGTCGAGTTGTTCAAGCCGATGGCAGTTAAGGCCATCAGAACCGAGGTGCTTGGAGGTCTAGGAGGATTCGCTGGGTTGTTCGCTCTACGCAGCGGCTACCGCGAACCGGTGTTAGCGGCTTCCACCGACGGTGTTGGTACCAAGCTGGCAGTCGCTCAGGCGATGGATAAGCACGACACCGTTGGCTTGGACCTGGTGGCGATGGTGGTCGACGACCTGGTGGTCTGTGGCGCTGAGCCACTGTTTTTGCAGGACTACATTGCTGTCGGCCGAACGGTGCCGGAACGACTGAGCGCGATCGTCGACGGTATTGCCGAGGGGTGCATGCTCGCGGGCTGTGCGTTACTGGGTGGTGAGACCGCAGAACACCCTGGTCTGATGGAAGTCGACCACTACGACATCGCGGCGACCGGCGTCGGTGTTGTGGAAGCCGACGATACCCTGGGGCCAGATCGTGTCAAACCCGGTGACGTAATCATCGCGCTGAGGTCTTCGGGTCTCCATTCCAACGGATACTCGCTGGCTCGCTCGGTCCTACTCGAGATCGATCGGATGAACCTGGCCGGTTATGTGGAGGAGTTCGGTCGCACCCTGGGCGAAGAGCTATTGGAGCCCACCCGCATCTACGCCAAGGACTGTCTGGCATTGGCGGCCGAAACTCACGTCCGTACCTTCTGTCACGTTACCGGCGGCGGGCTGGCCGGCAATCTTCAACGCGTTATCCCACACGGATTGGTCGCCGAAGTTGACCGCGGCACGTGGACACCTGCACCGGTGTTCGCCATGATAGCCCAGCGTGGCAGGGTCGCGCGTGAAGAGATGGAAAAGACGTTCAACATGGGCGTCGGCATGATCGCCGTGGTCGCGCCTGAAGATACTGACCGTGCTTTGGCGATATTGACCGCACGTCACTTGGACTGCTGGGTGCTGGGCACTGTCTGCAAAGGCAGCAAAGTAGGCCCACGGGCAAAACTGGTCGGACAACACCCGAG

Protein Sequence 

>ML2205c_PurM_protein
YRDDGSRKKPRRPAGQSWHHLCVDRGGH_SR_PLGRVVQADGS_GHQNRGAWRSRRIRWVVRSTQRLPRTGVSGFHRRCWYQAGSRSGDG_ARHRWLGPGGDGGRRPGGLWR_ATVFAGLHCCRPNGAGTTERDRRRYCRGVHARGLCVTGW_DRRTPWSDGSRPLRHRGDRRRCCGSRRYPGARSCQTR_RNHRAEVFGSPFQRILAGSLGPTRDRSDEPGRLCGGVRSHPGRRAIGAHPHLRQGLSGIGGRNSRPYLLSRYRRRAGRQSSTRYPTRIGRRS_PRHVDTCTGVRHDSPAWQGRA_RDGKDVQHGRRHDRRGRA_RY_PCFGDIDRTSLGLLGAGHCLQRQQSRPTGKTGRTTPE

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PurM with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

3 show intermediate predicted evidence for PPIs

21 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PurM

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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