purF
mL2206c
AMIDOPHOSPHORIBOSYLTRANSFERASE PURF (GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE) (GPATASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2620622 – 2622292
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2206c_purF_dna
CTAAACTGTGTGTTTGGCTGTCGGGGTAGGTGTCCGGGCACCTAAACACGTGCCACAGATTCGTCGACTGGGCCGTGCTGGCCGTAGACTCCGTTGCGTCACCAACTGCGCCCTAGGGAGCTGCCCAATCGTGACCGTCCAGCAACCCGGGCGGGATTTCAGCTCGCCCCGCGAAGAGTGCGGTGTGTTCGGGGTCTGGGCTCCGGGTGAACTAGTCGCCAAACTCACTTATTTCGGTCTATACGCGTTGCAGCATCGCGGCCAGGAAGCTGCGGGGATCGCTGTCGCTGATGGATCGCAGGTGTTGGTCTTCAAAGACCTTGGCTTAGTTAGTCAAGTGTTCGACGAGCAGACATTGGCGGCGATGGAGGGTCACGTTGCCATCGGTCATTGCCGCTACTCCACCACCGGCGACACCACCTGGGAAAATGCCCAGCCTGTTTTCCGCAACATCGCTGCCGGATCCGGGGTTGCGTTGGGGCACAACGGAAACCTGGTCAACACTGCCGAGCTTGCCGCACGTGCCCGCGACGCGGGGTTGATAGCAAAACGCTGCCCGGCCCCAGCGACAACGGACTCCGACATCCTGGGCGCGCTGTTAGCCCACGGTGCGGCCGACTCGACCCTGGAACAGGCTGCGCTGGAACTGCTGCCGACCGTGCGGGGTGCGTTCTGCCTGACATTCATGGACGAAAACACCCTCTATGCCTGCCGGGACCCGTATGGAGTACGGCCGCTGTCGCTCGGACGACTGGATCGCGGCTGGGTGGTGGCTTCTGAAACGGCGGGGCTCGACATTGTCGGCGCCTCGTTTGTCCGCGACATCGAGCCGGGCGAATTGCTGGCGATCGACGCCGACGGAGTACGGTCCACTCGTTTCGCCAACCCTACGCCCAAGGGTTGTGTTTTTGAGTACGTTTACCTGGCACGGCCCGACAGCACGCTGGCCGGACGGTCGGTGCACGGCACTCGGGTGGAGATCGGTCGTCGACTTGCCCGCGAATGCCCGGTCGAGGCCGACTTGGTGATCGGTGTGCCCGAATCAGGCACTCCCGCCGCAGTGGGATACGCGCAGGAATCCGGCATCTCTTACGGGCAGGGTCTGATGAAGAATGCATATGTTGGACGCACATTCATCCAACCGTCGCAAACCATCCGTCAACTGGGCATCCGGCTGAAGCTCAATCCGCTTAAAGAGGTAATCCGCGGCAAGCGGCTGATTGTTGTCGACGACTCGGTTGTGCGGGGGAACACCCAACGCGCTCTGGTGCGGATGCTGCGCGAGGCCGGTGCCGTCGAGCTGCACGTGCGCATCGCTTCACCACCGGTGAAGTGGCCCTGTTTTTACGGCATCGACTTCCCATCGCCGGCCGAATTGATCGCTAACGTCGTCGCAGACGAGGAGGAGATGCTCGAGGCGGTACGGCAGGGCATCGGTGCCGACACACTGGGCTACATCTCGCTGCGGGGCATGATTGCGGCTTCCGAGCAGCCCGCTTCGCGGCTGTGTTACGCTTGCTTTGACGGTAGGTATCCGATCGAGCTGCCCAGTGAAGCCATGTTAGGCAAAAATGTCATCGAGCACATGCTTGCCAATGCGGCGCGTGGAGCCGGGCTACGCGATCTTGCTGCTGATCAGGTCCCAGTCGATGCGGACGAAAATTGCGTTTG

Protein Sequence 

>ML2206c_PurF_protein
LNCVFGCRGRCPGT_TRATDSSTGPCWP_TPLRHQLRPRELPNRDRPATRAGFQLAPRRVRCVRGLGSG_TSRQTHLFRSIRVAASRPGSCGDRCR_WIAGVGLQRPWLS_SSVRRADIGGDGGSRCHRSLPLLHHRRHHLGKCPACFPQHRCRIRGCVGAQRKPGQHCRACRTCPRRGVDSKTLPGPSDNGLRHPGRAVSPRCGRLDPGTGCAGTAADRAGCVLPDIHGRKHPLCLPGPVWSTAAVARTTGSRLGGGF_NGGARHCRRLVCPRHRAGRIAGDRRRRSTVHSFRQPYAQGLCF_VRLPGTARQHAGRTVGARHSGGDRSSTCPRMPGRGRLGDRCARIRHSRRSGIRAGIRHLLRAGSDEECICWTHIHPTVANHPSTGHPAEAQSA_RGNPRQAADCCRRLGCAGEHPTRSGADAARGRCRRAARAHRFTTGEVALFLRHRLPIAGRIDR_RRRRRGGDARGGTAGHRCRHTGLHLAAGHDCGFRAARFAAVLRLL_R_VSDRAAQ_SHVRQKCHRAHACQCGAWSRATRSCC_SGPSRCGRKLRL

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PurF with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

39 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PurF

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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