ptrB
mL2226c
PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2642867 – 2645041
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2226c_ptrB_dna
CAGGAGCATGACAAAGACATCCAGGGGTACACCCGTACCGCCCATCGCCAAGCGCGTGGAGACTCGCAGGGAGCGCCACGGAGACGTCTTTTTTGATCCGTATGAATGGTTGCGCGACAATAACAATCCCGAAGTTGTTGCTTATCTCGATGCTGAAAACGATTACGTCAACCAGATGACTGCCCACCTTGAGCCGTTGCAGCAGAAGATTTTCAATGAGATCAAGGCGCGTACTAAGGAAAACGACCTGTCGGTGCCGACTCGCCAAGCCAACTGGTGGTACTATTCCCGCACCTTCGAGGGTAAGCAATATCGCGTCCAGTGTCGTTGTCCGGTAGCAAGTCCCGATGACTGGACTCCGCCGGCCCTATACGAGAACACTGAAATATCCGGTGAGCAGGTTTTGCTCGATTCGAATGCTGAGGCGGAGGGCCATGCCTTTTTTGCACTGGGTACCTTCATGGTCAGTTTGGATTCCAATCTGCTAGCTTATTCTGTGGACTTCGTCGGTGACGAGCGGTATACGCTGCGGTTCAAGGACTTACGTACCGGAGAACGATACCCTGACGAGATTGTGGGTATCGGCGCCGGAGCGACCTGGGCTGCTGACAACCGCACCGTGTACTATCTGACTTTGGATGAGTCCCGGCGTCCGGATACAGTGTGGCGGTGTCGGCTCGGCTCCGGTCAGCCGTCGGAGCAAGTTTATCATGAAGCTGATGAACGGTTCTGGCTCGCGGTCGGCCTTAGCCGAAGTGAAGCTTACATATTTATAGCCGCCGGGTCGGCCATCACCTCCGAGTGGCGCTACGCGGACTCGACTAACCCGGATGCGCAGTTCACCGTCGTGTTACCACGGCGTGACGGCATCGAGTACTCGGTAGAACATGCCCCCAGCGGCCTAGTCGGGGGACAAGACCGGTTCTTGATTTTACACAATGACGGTGCGGTGAACTTCACACTGGTGGAGTCACCGGTTAGCAATCCAGAACAGCAGCGCACCCTGATTCCACATCGCGACGACGTTCGACTGGACAGTGCTGATGCCTTCGCTGGCTATCTGGTGGTCAGCTATCGACGTGAGGCGTTGCCCCGGGTTCAGTTGTGGCCTATCGACCCCGACGGGAGCTACGGAGAGCCGGAAGAGATCTCGTTCGAGTCTGAACTGATGTGGGTCAGCCTGGAAGCCAATTCGAACTGGGTTTCGCCCAAACTGCGGATCCGGGCAGGATCGTTTGTCACCCCGGTCCGTGTCTATGACGTGGATTTGGCTACCGGTGAGCGGACGTTGCTACGCGAGCAGCCCGTTCTCGGCGGCTACAAGCATGAGGACTATGTTGAACGGCGTGAATGGGCGCAGGCGGATGACGGCACCTGGATCCCAGTGTCGATCGTTCATCGCGCCGCTATCCGATTTCCTGCTCCGGCAGTGCTTTACGGCTATGGTGCATACGAGATTTGTGTGGATCCGAGTTTTTCCATACCGCGGCTGTCGCTGCTGGACCGGGGAATGATGTTTGTCATTGCTCACGTTCGGGGCGGTGGTGAAATGGGACGGCTGTGGTACGAGCATGGCAAGCTCTTGGAGAAGAAGAACACGTTTACTGACTTCATTTCGGTGGCAAAGCATTTGGTGGATTCAGGGCAGACACGATCACAAGAATTAGTAGCATTGGGCGGTAGCGCGGGAGGCCTGTTGATGGGAGTGGTAGCTAACATAGCACCGGATCTCTTCACCGGAATCCTCGCTCAGGTGCCGTTTGTTGATCCGCTGACCACTATGCTGGATCCCTCGTTACCTCTGACCGTAACGGAGTGGGATGAATGGGGAAATCCGTTGATTGACAGTGATTTTTACTCATATATTAAGTCTTATTCTCCCTATGAGAACGTCGAAGCCAAACAATATCCTGCCATCTTGGCTATGACATCACTGCACGATACCAGGGTCCACTATGTAGAGCCGGCGAAGTGGATTGCAGCACTGCGGCACACAAAGAGTGACGGGAATCCAGTGTTGTTGAAAACCCAGATGGCCGCGGGCCATGCTGGCATAAGCGGACGCTACAAGGCTTGGCAGGAAACCGCGTTCCAATATGCTTGGCTGCTAGCTGCTGTCGACGTCGATCAGTATGGCACCGCCACCGAGGTAGATGACCTCGGTGGCGGTGCGCA

Protein Sequence 

>ML2226c_PtrB_protein
QEHDKDIQGYTRTAHRQARGDSQGAPRRRLF_SV_MVARQ_QSRSCCLSRC_KRLRQPDDCPP_AVAAEDFQ_DQGAY_GKRPVGADSPSQLVVLFPHLRG_AISRPVSLSGSKSR_LDSAGPIREH_NIR_AGFARFEC_GGGPCLFCTGYLHGQFGFQSASLFCGLRR_RAVYAAVQGLTYRRTIP_RDCGYRRRSDLGC_QPHRVLSDFG_VPASGYSVAVSARLRSAVGASLS_S__TVLARGRP_PK_SLHIYSRRVGHHLRVALRGLD_PGCAVHRRVTTA_RHRVLGRTCPQRPSRGTRPVLDFTQ_RCGELHTGGVTG_QSRTAAHPDSTSRRRSTGQC_CLRWLSGGQLST_GVAPGSVVAYRPRRELRRAGRDLVRV_TDVGQPGSQFELGFAQTADPGRIVCHPGPCL_RGFGYR_ADVATRAARSRRLQA_GLC_TA_MGAGG_RHLDPSVDRSSRRYPISCSGSALRLWCIRDLCGSEFFHTAAVAAGPGNDVCHCSRSGRW_NGTAVVRAWQALGEEEHVY_LHFGGKAFGGFRADTITRISSIGR_RGRPVDGSGS_HSTGSLHRNPRSGAVC_SADHYAGSLVTSDRNGVG_MGKSVD_Q_FLLIY_VLFSL_ERRSQTISCHLGYDITARYQGPLCRAGEVDCSTAAHKE_RESSVVENPDGRGPCWHKRTLQGLAGNRVPICLAASCCRRRSVWHRHRGR_PRWRCA

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PtrB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

32 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PtrB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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