purB
mL2230c
PROBABLE ADENYLOSUCCINATE LYASE PURB (ADENYLOSUCCINASE) (ASL) (ASASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2647530 – 2648948
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2230c_purB_dna
TGCTTCTGTGAGCATTCCGAATGTTCTAGCCGCCCGATACGCCAGCGCTGAATTGGTCGCGATATGGTCTCCGGAAGCCAGGGTTATCGCGGAGCGGCAGTTGTGGCTGGCCGTGCTACGAGCACAGGCGGAACTGAGTGTTCCGATGCCTGTTAAAGCGATCGCCGACTACGAGCGGGTGCTTGGCGAGGTCGATTTGGCTTCGATCGCCGCCCGCGAACGTGTGTTGCGTCACGACGTCAAGGCGCGCATCGAGGAATTCAACGCGCTGGCCGGCCATGAGCAGGTACATAAGGGGATGACCAGCCGCGACTTGACCGAGAACGTGGAGCAACTGCAGATCCGGCGGTCGTTGGAATTGGTTTTCTGCCATGGTGTGGCCGTAGTAGCACGGCTGGCCGAATGCGCGGTGTCCTATCGCGACCTGGTGATGGCCGGACGCAGCCATAACGTTGCCGCGCAGGCCACGACATTGGGCAAACGCTTCGCGTCCGCGACGCAGGAAACACTGATAGCGTTGACTAGGCTGCGCGAGTTGATCGACCGCTACCCACTGCGCGGTATCAAGGGCCCGATGGGTACCGGGCAGGACATGCTCGACCTGCTTGGCGGTGACGCTGCGGCGCTAGCAGAACTTGAGCAAAGAATAGCTGAATTCCTAGGATTCACAAAGGTTTTAGCCAGTGTCGGGCAGGTATATCCGCGTTCACTAGACCACGATGTGATTTCAGCGTTGGTGCAGCTCGGTGCCGGCTCTTCCTCGTTAGCGCACACCATACGGTTGATGGCAGGTCACGAGCTCGTTACCGAAGGCTTTGCACCGGGGCAGGTTGGCTCGTCAGCGATGCCACACAAGATGAACAGCCGCAGCTGTGAACGGGTCAACGGTCTGCAGGTGGTGTTGCGCGGTTACGCCGCAATGGCAGCCGAACTAGCTGGCGCGCAGTGGAACGAGGGCGACGTTTTCTGCTCAGTAGTACGTCGAGTTGCTTTGCCAGACAGCTTCTTTGCCATCGACGGCCAGATCGAGACGTTTTTGACGGTGCTCGACGAGTTTGGTGCTTACCCGGCAGTGATCCGCCGCGAGCTGGACCGCTATTTGCCATTCCTGGCCACCACCAAGGTGCTGATTGCGGCTGTGCGTGCTGGTATGGGTCGCGAGGCCGCTCACCACGTGATTCGCGAACACGCGGTGGCGACGGCGCTGGCCATGCGGGAGTGCGGTGCCGAGCCTGACCTGCTGGACCGGTTGGCTGCCGATGGGCGGTTGCCGCTGGACCGAGCGGCGCTAGACGCCGCGCTGGCCGACAAGAAGGCGTTCACCGGCGCCGCGGCAGACCAGGTAGACGAGGTTGTCGCGATGGTCGACAAGCTAGTGGGCCGCTACCCGGAAGCAGCCAAGTACACGCCGGGTGCTAT

Protein Sequence 

>ML2230c_PurB_protein
CFCEHSECSSRPIRQR_IGRDMVSGSQGYRGAAVVAGRATSTGGTECSDAC_SDRRLRAGAWRGRFGFDRRPRTCVASRRQGAHRGIQRAGRP_AGT_GDDQPRLDRERGATADPAVVGIGFLPWCGRSSTAGRMRGVLSRPGDGRTQP_RCRAGHDIGQTLRVRDAGNTDSVD_AARVDRPLPTARYQGPDGYRAGHARPAWR_RCGASRT_AKNS_IPRIHKGFSQCRAGISAFTRPRCDFSVGAARCRLFLVSAHHTVDGRSRARYRRLCTGAGWLVSDATQDEQPQL_TGQRSAGGVARLRRNGSRTSWRAVERGRRFLLSSTSSCFARQLLCHRRPDRDVFDGARRVWCLPGSDPPRAGPLFAIPGHHQGADCGCACWYGSRGRSPRDSRTRGGDGAGHAGVRCRA_PAGPVGCRWAVAAGPSGARRRAGRQEGVHRRRGRPGRRGCRDGRQASGPLPGSSQVHAGCY

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PurB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

1 shows weak predicted evidence for PPIs

View all pooled AlphaFold results for PurB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.