menE
mL2257c
POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2681384 – 2682490
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2257c_menE_dna
AGCTCCATTGTTGCTGCCCACGCTGGAACGAATCCTGGATGGCCGCGCTCCCGCAATGGTCGTGGTACCGGCTCAGCATGAACCCATCGCTGCGCTGCGTGCTTTGCGAGTAGGTGAAGAGATCGACGACGATGTGGCTTTAGTGGCCACCACGTCGGGAACGACAGGTGTGCCCAAGGGCGCCTTGCTGACTGCCGCCGCCTTGACTGCCAGCGCGTCGGCCACCCACGACCGCCTTGGTGGTCCGGGCAGCTGGCTGCTGGCTTTGCCGCCGTATCATATCGGCGGGCTTCAGGTGCTGGTGCGTAGCGTGCTGGCCGGTTCGGTACCCATCGAGTTGGACATTTCTGCCGGGTTTGACCTCGCCAAACTGCCGGACGCGGTGGGTCGATTGGGTACCGGTCGACGATACACGTCACTGGTCGCTACCCAGCTGGCCAAGGCGCTCACCGACTCAACGGCCACGGCCGTGCTAGCCGAATTGGATGCCGTCCTCGTTGGTGGCGGACCAGCTCCCCGGCCGATCCTGGATGCCGCAACATCTGCCGGCATCATGGTGGTCGGCACCTATGGGATGAGCGAGACTGCGGGAGGTTGCGTTTACGACGGCGTCCCGCTGGATGGTGTGTGCATACGCGTACTGGTCAATGGCCACGTAGCGATCGGTGGTGCGACCTTGGCCAAGGGCTATCGCAATCCGATCGTTCCCGACCCGTTCGCCGAATCGGGTTGGTTCCACACAGACGACCTCGGTACTGTCGATGGCTCGGGTGTGCTAACAGTGCTGGGTCGGGCCGACGACGCGATCAGCACGGGTGGGCTAACCGTGCTGCCAGGACCCGTCGAAGCTGCGCTGTGCACCCATCCCGCGGTCAGCGACTGTGCGGTGTTCGGGCTTACTGACGACCGGCTAGGTCAGCGGGTAGTAGCCGCAGTGGTACTGACTGACGGTTACGCAACGCCGACGCTGAGCATGTTGCGGGCACATGTCACCCGCAGACTGGACGCCATGGCCGCACCGCGCGAGCTACACATCGTTGATACACTGCCACGACGTGGCATCGGAAAGGTCGATCGCACGGCGTTAGTGCGCCGGTTCGCCAAGTC

Protein Sequence 

>ML2257c_MenE_protein
SSIVAAHAGTNPGWPRSRNGRGTGSA_THRCAACFASR_RDRRRCGFSGHHVGNDRCAQGRLADCRRLDCQRVGHPRPPWWSGQLAAGFAAVSYRRASGAGA_RAGRFGTHRVGHFCRV_PRQTAGRGGSIGYRSTIHVTGRYPAGQGAHRLNGHGRASRIGCRPRWWRTSSPADPGCRNICRHHGGRHLWDERDCGRLRLRRRPAGWCVHTRTGQWPRSDRWCDLGQGLSQSDRSRPVRRIGLVPHRRPRYCRWLGCANSAGSGRRRDQHGWANRAARTRRSCAVHPSRGQRLCGVRAY_RPARSAGSSRSGTD_RLRNADAEHVAGTCHPQTGRHGRTARATHR_YTATTWHRKGRSHGVSAPVRQV

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding MenE with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

13 show weak predicted evidence for PPIs

View all pooled AlphaFold results for MenE

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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