menC
mL2268
PROBABLE MUCONATE CYCLOISOMERASE MENC (CIS%2CCIS-MUCONATE LACTONIZING ENZYME) (MLE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2691804 – 2692808
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2268_menC_dna
CCACCCTGACGGAGTTGTTGGACCGGCTACATGTAGTGGCTCTGCCGATGCGGGTGCGCTTCCGCGGCATCACCACCCGCGAAGTGGCGCTGATCGACGGCCCAGCAGGATGGGGAGAGTTCGGGGCCTTCCTCGAATACCAGCCCTTAGAGGCGTCCGCGTGGCTGGTGGCGGGCATTGAGGCCGCTTACGGTGAGCCACCGGAGGGTCGCCGTGACCGGATCCCGATCAACGCCACCGTGCCAGCCGTGTCCGCCACCCAGGTACCCGAGGTGCTTGCCCGCTTTCCTGGCGTGCGCACCGCCAAGGTTAAAGTGGCCGAGCCCGGACAAAACCTCGCCGACGATGTCGACCGGGTCAACGCGGTGCGGGAACTGGTGGAAACCGTGCGAGTAGACGCTAATGGTGGCTGGAGCGTCGAGGCGGCGGCCCAGGCGGCCGTTGCCCTGACCGCCGACGGCCCGCTAGAGTACTTAGAACAACCGTGTGCCACAGTCGCCGAGCTCGCCGCGCTGCGCCGCCGGGTCGACATACCGATCGCTGCTGACGAAAGCATCCGCAAGGCCGACGACCCGTTGGCGGTGGTCCGCTCGCACGCTGCCGACGTTGCAGTGCTGAAAGTCGCGCCGCTGGGCGGGATTGCATCGTTCCTGGCTATCGCAGCGCAGATCGATATCCCGGTGGTGGTTTCCAGCGCGCTAGATTCGGTGGTCGGGATCACCGCCGGACTGATCGCCGCCGCGGCCCTACCCGAACTCGACTACGCCTGCGGGCTGGGCACCGGCAGGCTGTTCGTCGCAGACGTCGCCGAACCTATGCTGCCTGTCGATGGTTTCCTTCCGGTCGGACCGGTAACGCCTGACCCAGCGCGGCTGCAGGCGCTGGGCACGCCGCCTGCCCGACGGCAGTGGTGGATCGACCGAGTCAAGACCTGCTACTCGCTGCTTGTACCGTGTGCAGGTGATCAATCTGGCTTACGAAGACCGCGGGACCGGTGAACCTGTT

Protein Sequence 

>ML2268_MenC_protein
PP_RSCWTGYM_WLCRCGCASAASPPAKWR_STAQQDGESSGPSSNTSP_RRPRGWWRALRPLTVSHRRVAVTGSRSTPPCQPCPPPRYPRCLPAFLACAPPRLKWPSPDKTSPTMSTGSTRCGNWWKPCE_TLMVAGASRRRPRRPLP_PPTAR_ST_NNRVPQSPSSPRCAAGSTYRSLLTKASARPTTRWRWSARTLPTLQC_KSRRWAGLHRSWLSQRRSISRWWFPAR_IRWSGSPPD_SPPRPYPNSTTPAGWAPAGCSSQTSPNLCCLSMVSFRSDR_RLTQRGCRRWARRLPDGSGGSTESRPATRCLYRVQVINLAYEDRGTGEPV

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding MenC with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

11 show weak predicted evidence for PPIs

View all pooled AlphaFold results for MenC

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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