menH
mL2273
PROBABLE UBIQUINONE/MENAQUINONE BIOSYNTHESIS METHYLTRANSFERASE MENH (2-heptaprenyl-1%2C4-naphthoquinone methyltransferase)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2697290 – 2698006
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2273_menH_dna
CCGGTAGCGTCGACGTCGTGAGTCGCGCTGCCCTGGACAAGGACCCCCGGGATGTCGTAGCGATGTTCGACGACGTCGCCCACCGATACGATCTGACCAACACTGTGCTGTCGCTGGGTCAAGATCGGTACTGGCGACGAGCCACGCGGTCGGCGCTGCGGATTGGGCCCGGGCAGAAAGTGCTGGACCTGGCCGCAGGCACGGCGGTGTCCACAGCGGAACTGAGTAAATCCGGCGCCTGGTGTGTGGCTGCGGATTTTTCGGTCAGGATGCTAGCAACCGGCGGTGCGCGAAAGGTACCTAAGGTGGCCGCAGATGCCACCCAACTTCCCTTTAGCGATGGTGTATTCGATGCAGTCACTATCAGTTTCGGGTTGCGCAATATCGCCGACTATCAGGCGGCGCTGCGCGAGATGGCCCGCGTCACCCGGCCCGGCGGTCAATTAGTAGTGTGCGAGTTCTCCACACCCACCAATGCGCTGGTCGCCAATGTCTACACGGAATACCTGATGCGGGCACTGCCGCAAGTGGCGCGACTGGTGTCTAGTAATCCCGATGCCTACATCTACTTGGCGGAGTCCATCAGAGCCTGGCCCGATCAGGTTACGCTGGCCTGCCAGCTGTCGCGGACCGGTTGGGCGTCGCCGCGCTGGCGTAACCTCACCGGCGGAATTGTGGCTTTGCATGCAGCAGATAAGCCGGTGCGGTAAGCCGACC

Protein Sequence 

>ML2273_MenH_protein
PVASTS_VALPWTRTPGMS_RCSTTSPTDTI_PTLCCRWVKIGTGDEPRGRRCGLGPGRKCWTWPQARRCPQRN_VNPAPGVWLRIFRSGC_QPAVRERYLRWPQMPPNFPLAMVYSMQSLSVSGCAISPTIRRRCARWPASPGPAVN__CASSPHPPMRWSPMSTRNT_CGHCRKWRDWCLVIPMPTSTWRSPSEPGPIRLRWPASCRGPVGRRRAGVTSPAELWLCMQQISRCGKPT

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding MenH with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

38 show weak predicted evidence for PPIs

View all pooled AlphaFold results for MenH

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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