grcC1
mL2277
PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2700171 – 2701163
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2277_grcC1_dna
TAGCGGGCATTAATTTCGGAGACGCTGCGTTTGCGGCGACTGTACAAGACAGGGTAGTGAGGATCGAGCAACTCATGGATGCCGAGTTGCGAGACACGGACGAGGTGATGACCGAGTCAGTACTACACTTGTTCGCAGCCGGTGGTAAGCGGTTCCGACCGCTGTTTACAGTGCTATCCGCCCAGATCGGACCCCGGCCCGACGCTCCAGAAGTTATAATAGCCGGTGCGGTCATTGAACTGGTCCACCTAGCGTCGCTTTACCACGACGACGTGATGGACGAGGCCGAGGTCCGGCGCGGGGCGCCCAGTGCCAACCTGCGATGGAGTAACAGCGTTGCCATTCTTGCCGGCGATTATCTATTTGCTACGGCGTCGCGGTTGGTATCACAGCTTGGACTGGATGCTGTGCGGATTATCGCTGACACGTTTGCCCAGCTGGTGACCGGGCAGATGCGCGAAACCCGCGGTGTGCCGGAAGGTGCAGATTCGATCGAGCAGTACCTGAAGGTGGTGTATGAAAAAACGGGTTGTCTGATCGGCTCGGCTGGTCGGCTTGGTGGTTTGTTTGCTGGCGCACACGCCGAGCAGGTCGAGCGGCTGAGCCGACTCGGGAGCATCGTGGGCACCGCGTTTCAGATTTCCGACGACATCATCGATATCGACAGCGACTACACCAAGTCCGGCAAGCTTCCCGGCACAGATGTGCGTGAAGGCGTGCGCACTTTACCGATACTCTATGCGCTGCGTGAGACCGGGCCCGATAGCGAGCGGCTACGAGCACTGTTGGCCGGACCCGTCGACAACGACGCAGAGGTAGTCGAAGCACTAGCGCTGTTGCGGGCGTCGCCCGGGATGGCGAGGGCCAGGCAAGTGTTGGCGCATTACGCGGACCAGGCCAGTGGCGAGCTGGCTCAGTTGCCCGACGGCCCCAGTCGGGATGCGCTGGCGACTCTGGTCGACTACACAACCAACCGGCACGGTTAGAGCGCAG

Protein Sequence 

>ML2277_GrcC1_protein
RALISETLRLRRLYKTG__GSSNSWMPSCETRTR__PSQYYTCSQPVVSGSDRCLQCYPPRSDPGPTLQKL__PVRSLNWST_RRFTTTT_WTRPRSGAGRPVPTCDGVTALPFLPAIIYLLRRRGWYHSLDWMLCGLSLTRLPSW_PGRCAKPAVCRKVQIRSSST_RWCMKKRVV_SARLVGLVVCLLAHTPSRSSG_ADSGASWAPRFRFPTTSSISTATTPSPASFPAQMCVKACALYRYSMRCVRPGPIASGYEHCWPDPSTTTQR_SKH_RCCGRRPGWRGPGKCWRITRTRPVASWLSCPTAPVGMRWRLWSTTQPTGTVRAQ

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding GrcC1 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

13 show weak predicted evidence for PPIs

View all pooled AlphaFold results for GrcC1

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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