ephE
mL2297
POSSIBLE EPOXIDE HYDROLASE EPHE (EPOXIDE HYDRATASE) (ARENE-OXIDE HYDRATASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2722017 – 2722991
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2297_ephE_dna
TGTCGAACCCGTCGGTGACCCGTATCGCCGGGCCATGGCACCATCTGGACGTGCACGCCAACGGCATCCGATTCCACGTCGTCGAGGCGGTGCCCACCCAGCCAGCCGGCCAGGACTGCGCCCCTTCGGCTACGGCACGACCACTGGTAATGCTGCTGCATGGTTTCGGTTCTTTCTGGTGGTCCTGGCGTCATCAGCTACGCGGCCTGACCGAAGCGCGACTGGTCGCGGTGGACCTGCGTGGCTACGGTGGCAGCGACAAACCGCCCCGCGGCTATGACGGCTGGACACTTGCCGGCGACACAGCCGGGCTCATCCGAGCACTGGGGCACTCATCGGCGACACTGGTTGGCCACGCCGAAGGCGGGCTTGCGTGCTGGGCCACCGCGCTGCTGCACCCACGGCTGGTGCGCGCCATTGCCCTGATCAACTCACCGCACCCAGCAGCGTTACGACGATCAATGCTGACGCACCGTAATCAAGGTTACGCACTGCTGCCGACGTTGCTACGCTACCAGTTACCAATTTGGCCGGAACGTTTGCTGACCCGCAATAACGCAGCGGAGATCGAACGCCTAGTCCGCAGTCGCAGCAGTGCCAAATGGCAAGCTTGCGAGGATTTCGCGGTCACGATCGACCATTTGCGTATAGCGATCCAGATTCCGGCTGCCGCGCACTGTGCACTCGAGTATCAGCGTTGGGCAGTGCGTAGCCAGCTACGTAACGAAGGCCGTAAATTCATGAAATCGATGTCTCGACCATTCAGCGTACCGCTGCTGCACGTACGCGGCGACGCGGATCCCTACCTGCTAGCCGACTCGGTGGACCGAACACGGCGCTATGCACCGCACGGACGCTACGTATCCGTTTCCGACGCAGGACATTTCAGTCACGAAGAAGCACCAGAGGAAATTAACAGATACCTGACGCGGTTTCTCAAGCAGGTTCACGGGCCCCGGCTCAGCTGACGCAGGC

Protein Sequence 

>ML2297_EphE_protein
CRTRR_PVSPGHGTIWTCTPTASDSTSSRRCPPSQPARTAPLRLRHDHW_CCCMVSVLSGGPGVISYAA_PKRDWSRWTCVATVAATNRPAAMTAGHLPATQPGSSEHWGTHRRHWLATPKAGLRAGPPRCCTHGWCAPLP_STHRTQQRYDDQC_RTVIKVTHCCRRCYATSYQFGRNVC_PAITQRRSNA_SAVAAVPNGKLARISRSRSTICV_RSRFRLPRTVHSSISVGQCVASYVTKAVNS_NRCLDHSAYRCCTYAATRIPTC_PTRWTEHGAMHRTDATYPFPTQDISVTKKHQRKLTDT_RGFSSRFTGPGSADAG

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EphE with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

25 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EphE

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.