nth
mL2301c
PROBABLE ENDONUCLEASE III NTH (DNA-(APURINIC OR APYRIMIDINIC SITE)LYASE) (AP LYASE) (AP ENDONUCLEASE CLASS I) (ENDODEOXYRIBONUCLEASE (APURINIC OR APYRIMIDINIC)) (DEOXYRIBONUCLEASE (APURINIC OR APYRIMIDINIC))
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2725730 – 2726491
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2301c_nth_dna
TAAAGTAATGCCCCTCACGCCTGGTGTCGACGTGGCCCGGCGCTGGTCCGGGGAAACCAGACTGGGTTTGGTGCGACGGGCGCGGAGGATGAATCGTGCATTGGCGCAAGCATTTCCGCATGTGTACTGTGAATTGGATTTCACGTCGCCGCTGGAGTTGACGGTGGCCACCATCCTTTCGGCGCAGAGCACCGATAAGCGGGTGAACTTGACGACACCAGCTGTGTTTGCGCGTTACCGGTCGGCGCTGGACTACATGCAAGCGGATCGCGCTGAACTAGAAAACTTCATACGTCCTACGGGTTTCTTCCGTAACAAGGCGGCTTCGCTTATCAGGCTCGGGCAGGCCTTGGTCGAGCGGTTCGATGGCGAGGTGCCCTCGACCATGGTTGACCTGTTTACGTTACCCGGTGTAGGACGCAAGACCGCTAATGTCATTCTGGGAAATGCGTTCGGTATCCCCGGGATCACTGTCGACACGCATTTTGGACGATTAGTGCGGCGATGGCGTTGGACGGCCGAAGAGGATCCAGTCAAGGTGGAGCATGCTGTCGGTGAACTGATCGAACGCGATCAGTGGACTTTGCTGAGCCACCGAGTGATCTTCCACGGTCGTCGGGTGTGCCACGCGCGCAAACCGGCATGCGGTGTTTGCGTACTTGCCAAGGACTGTCCCTCCTTCGGCCTTGGCCCCACTGAACCGCTGCTGGCCGCGCCTCTCGTCCAAGGCCCGGAAGCCGGGCACTTGCTGGCCCTGGCTGG

Protein Sequence 

>ML2301c_Nth_protein
SNAPHAWCRRGPALVRGNQTGFGATGAEDESCIGASISACVL_IGFHVAAGVDGGHHPFGAEHR_AGELDDTSCVCALPVGAGLHASGSR_TRKLHTSYGFLP_QGGFAYQARAGLGRAVRWRGALDHG_PVYVTRCRTQDR_CHSGKCVRYPRDHCRHAFWTISAAMALDGRRGSSQGGACCR_TDRTRSVDFAEPPSDLPRSSGVPRAQTGMRCLRTCQGLSLLRPWPH_TAAGRASRPRPGSRALAGPGW

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Nth with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

3 show intermediate predicted evidence for PPIs

38 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Nth

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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