glpK
mL2314c
PROBABLE GLYCEROL KINASE GLPK (ATP:GLYCEROL 3-PHOSPHOTRANSFERASE)(GLYCEROKINASE) (GK)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2741820 – 2743346
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2314c_glpK_dna
AGCGCAGTTGGCCGAGTTCGCTGAATTCATAGCCGCCATCGACCAGGGCACCACCAGCACCCGCTGCGTGATTTTCGATCATAATGGTGCTGAGGTGGCCCGCCACCAGCTTGAGCACGAGCAAATCTTGCCCCGCTCCGGCTGGGTCGAACATAATCCCGTTGAGATTTGGGAACGCACCGCGTCAGTGCTGATGTCGGTGCTGAACGCCACTAATTTGTCAGCTAAAGATATTGCAGCGCTTGGAATTACTAACCAACGTGAGACTACCCTGGTGTGGAATCGGAACACCGGAAGGCCGTATTGCAATGCGATCGTTTGGCAAGACACCCGCACTGACCGTATCGCGGTCGCGCTTGACCGAGATGGCCGCGGAGAGGTGATCCGCCGCAAAGCCGGGTTGCCGCCGGCGACCTATTTTTCCGGCGGGAAATTGCAATGGATCTTAGAGAACGTCGACGGGGTAGGCGCCGCTGCTGAAAACGGTGAAGCACTCTTCGGCACCCCCGATACCTGGTTATTGTGGAATCTGACCGGTGGTCCGCGGGGTGGCGTACACGTCACCGATGTGACCAACGCTAGCCGGACCATGCTGATGGACTTAGAGAAGCTGGATTGGGACGACGAGCTGTTGTCGTTTTTTTCCATCCCTCGGGCGATGTTGCCGGCGATCGCGTCGTCTTCACCGCTGCAGCCCTACGGTGTCACTTTAGCGGACGGACCCGTCGGTGGTGAAGTGCCGATCACAGGAGTCTTGGGCGATCAGCATGCGGCGATGGTTGGTCAGGTGTGTCTAGACGCGGGGGAAGCGAAAAACACTTACGGCACCGGCAATTTTTTGCTGCTTAACACCGGTGAGGCTATCGTGAGATCCGGTAACGGCCTGTTGACCACCGTTTGCTATCAGTTCGGGGATGCCAAACCCGTCTACGCGCTTGAAGGTTCGATCGCGGTGACTGGCTCAGCGGTGCAGTGGTTACGTGATCAGTTGGGCATCATCAGCGGCGCTGCTCAAAGCGAATCGCTGGCCCGTCAGGTCGTTGACAATGGCGGGGTGTACTTCGTACCGGCATTTTCCGGGTTGTTTTCCCCGTATTGGCGGTCCGATGCACGAGGCGCAATTGTGGGGCTATCACGGTTCAACACCAACGCGCATCTGGCCCGCGCGACGTTGGAAGCTATCTGTTATCAGAGTCGGGACGTGGTGGACGCGATGGCAGCAGATTCTGGTGTGCGCCTTGATGTCTTGAAGGTCGATGGTGGTATCACCAGTAATGACTTGTGCATGCAGATTCAGGCCGACGTGCTGGGCGTGGACGTGGTACGCTCGGTAGTTGCTGAGACTACTGCGCTGGGCTCTGCCTATGCGGCGGGTCTAGCGGTCGGGTTTTGGGCTGGTCCGTCAGATCTACGGGCCAATTGGCAAGAGGATAAGCGTTGGACGCCGACGTGGGGCGAGGACCAGCGTGCCGCGGCGTATGCGGGTTGGCGTAAAGCCGTGCAGCGGACGTTGGATTGGGTCGATGT

Protein Sequence 

>ML2314c_GlpK_protein
SAVGRVR_IHSRHRPGHHQHPLRDFRS_WC_GGPPPA_ARANLAPLRLGRT_SR_DLGTHRVSADVGAERH_FVS_RYCSAWNY_PT_DYPGVESEHRKAVLQCDRLARHPH_PYRGRA_PRWPRRGDPPQSRVAAGDLFFRREIAMDLRERRRGRRRC_KR_STLRHPRYLVIVESDRWSAGWRTRHRCDQR_PDHADGLREAGLGRRAVVVFFHPSGDVAGDRVVFTAAALRCHFSGRTRRW_SADHRSLGRSACGDGWSGVSRRGGSEKHLRHRQFFAA_HR_GYREIR_RPVDHRLLSVRGCQTRLRA_RFDRGDWLSGAVVT_SVGHHQRRCSKRIAGPSGR_QWRGVLRTGIFRVVFPVLAVRCTRRNCGAITVQHQRASGPRDVGSYLLSESGRGGRDGSRFWCAP_CLEGRWWYHQ__LVHADSGRRAGRGRGTLGSC_DYCAGLCLCGGSSGRVLGWSVRSTGQLARG_ALDADVGRGPACRGVCGLA_SRAADVGLGRC

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding GlpK with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

24 show weak predicted evidence for PPIs

View all pooled AlphaFold results for GlpK

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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