dnaZX
mL2335c
DNA POLYMERASE III (SUBUNIT GAMMA/TAU) DNAZ/X
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2765714 – 2767549
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2335c_dnaZX_dna
TGCTGACGTGACTCTGTACCGCAAGTATCGACCGGCAGCTTTCGCTGAGGTGGTGGGGCAAGAACATGTCACCGAGCCGCTGTCTATCGCTTTGGAAGCCGGAAGGATCAACCATGCTTACTTGTTCTCCGGGCCGCGTGGCTGTGGAAAGACCTCTTCGGCGCGCATTCTGGCGCGGTCGCTTAATTGTGCGCAGGGGACCACGGCCACGCCGTGTGGTGTATGCGAATCATGCTTGTCTTTGGCGCCCAACGCGCCCGGCCACATCGACGTGGTGGAGCTTGACGCCGCCAGCCACGGCGGCGTGGACGACACTCGTGAGCTGCGCGACCGCGCGTTCTACGCGCCGGCCCAGTCACGGTACCGTGTGTTCATTGTCGACGAAGCGCACATGGTGACCACCGCCGGCTTTAACGCGCTACTCAAGATCGTCGAGGAACCGCCCGACCACTTGATCTTCATCTTCGCCACCACCGAGCCGGAGAAGGTGCTGCCGACGATTCGATCGCGCACCCATCATTACCCATTTAGGCTGCTGTCGCCACGCACCATGCGGGCTTTGGTCGGGCGCATCTGTGCGCAGGAGGGCGTCGTCGTCGACGATGCGGTGTACCCTCTGGTCATCCGGGCCGGTGGAGGTTCCCCCCGGGACACGCTGTCAGTGTTGGATCAGCTGGTGGCTGGCGCGGAAGGCGAGCACGTGACCTACCAGCGGGCGCTGAAGTTGCTAGGTGCCACCGACGTTGGACTTATAGACGACGCTGTCGATGCACTCGGGGCTCACGATGCGGCAGCATTGTTTGGTGCGGTCGAATCGGTGATTGATGCCGGCCACGATCCACGGCGTTTTGCTACTGATTTGCTAGAGCGATTCCGCGATCTCATCGTCCTGCAGGCGGTTCCTGATGCGGCAGCCCGTGGTGTGGTGGATGCTTCGGAGGATGTGTTAGACCGGATGCGGGAGCAAGCTGTCCGAATCGGACCGGCGACGTTGACCCGTTACGCCGAGGTGGTACACTCCGGGTTGGGGGAGATGCGTGGTGCAACGGCGCCGCGTCTGCTTCTCGAAGTGGTTTGCGCGCGGCTGTTGCTGCCTTCGGCCACGGACGCCGAGTCGGCATTGCTGCAACGGGTCGAGCGAATCGAGACCCGGCTGAACATGTCGATCCCCGCTGCCAGGGCAGCATACCCGCTTCAGTCAGCGCCCGCCGAGAAGGCTGCCCAACCTAGTCTCCCTCACCAGCCTTTCCTGGCTTCCCCGGATTCCCAGCCCGCTCCGGATGCTCAGTCTTCCAAACTGGCTACGCCACAGGCTGCCGCTGAACCAACCCCTGGCATGGGTGCACCCAATGCGGCCGCGGTACGAACCATGTGGTCGACGGTGCGTGAGAAGGTGCGCCAGCGCAGCCGCACTACCGAGGTGATGCTGGCGGGCGCGACCGTCCGCGCGGTTGAGGACAACACCTTGATTTTGACCCACGGATCGGCGCCACTGGCCAAGCGGCTGTCTGAACAGCACAACGTAGATGTTATCGCCGAAGCGCTCAAAGACGCGCTGGGTGTGAACTGGCGGGTGCGATGCGAGGCCGGCGTACCCGTGCCTGCTGTGGGTGCACTACCCGCTTGCGAGGGAATGGTTGCGCTGCCTACCCAGGAGAAAGTTCCTGTCCTTGACGTGGCTTCTGCCCAGCAGTATGAAGATGAGGGCATGCTAGCTGAACCCGGGCGTAGAGACCTGTCAGCACCGCGTCCCGACCTGGAAGAGGTTGCGCTCGAACTGTTGCAAAACGAACTGGGTGCCCGCCGTATCGATAAATGGCTGACTGACGCGGTTGA

Protein Sequence 

>ML2335c_DnaZX_protein
C_RDSVPQVSTGSFR_GGGARTCHRAAVYRFGSRKDQPCLLVLRAAWLWKDLFGAHSGAVA_LCAGDHGHAVWCMRIMLVFGAQRARPHRRGGA_RRQPRRRGRHS_AARPRVLRAGPVTVPCVHCRRSAHGDHRRL_RATQDRRGTARPLDLHLRHHRAGEGAADDSIAHPSLPI_AAVATHHAGFGRAHLCAGGRRRRRCGVPSGHPGRWRFPPGHAVSVGSAGGWRGRRARDLPAGAEVARCHRRWTYRRRCRCTRGSRCGSIVWCGRIGD_CRPRSTAFCY_FARAIPRSHRPAGGS_CGSPWCGGCFGGCVRPDAGASCPNRTGDVDPLRRGGTLRVGGDAWCNGAASASRSGLRAAVAAFGHGRRVGIAATGRANRDPAEHVDPRCQGSIPASVSARREGCPT_SPSPAFPGFPGFPARSGCSVFQTGYATGCR_TNPWHGCTQCGRGTNHVVDGA_EGAPAQPHYRGDAGGRDRPRG_GQHLDFDPRIGATGQAAV_TAQRRCYRRSAQRRAGCELAGAMRGRRTRACCGCTTRLRGNGCAAYPGESSCP_RGFCPAV_R_GHAS_TRA_RPVSTASRPGRGCARTVAKRTGCPPYR_MAD_RG

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding DnaZX with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

35 show weak predicted evidence for PPIs

View all pooled AlphaFold results for DnaZX

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.