ppsE
mL2353c
PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2794935 – 2799404
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2353c_ppsE_dna
GAAACCAGTGATTACCCCCGACAACGCGATCGCGGTGGTCGGCATGGCCGGCAAATTTCCGGGCGCCAACGATGTGTCGGCGTTCTGGACCAACCTTCGGCGCGGCAAGGAGTCGATCGTCACCCTGTCTGAGCAAGAGCTGCGCGACAACGGGGTCAGCGACAAAGCACTGGCCGATCCGGCGTATGTGCGTCGCGCACCGTTACTCGACGGGATCGACGAGTTTGATGCTGACTTCTTCGGTCTGCCGCCGCTGGCCGCGCAGGTATTGGATCCACAACACCGGTTGTTCCTTCAGTGCGCGTGGCATGCGCTAGAGGATGCAGGTTGTGACCCCGCGCAGTTCGACGGCTCGATCGGAGTATACGGAACCAGTTCTCCCAGCGGTTATCTCTTGCATAACCTGTTGTCGCATCGCGACCCCCACACCGTTTTGGCTGAGGGACTCAACTTCGACCAGTTCAGTCTGTTCCTACAGAACGACAAAGACTTCTTGGCAACTCGGATATCGCACGCGTTCAACTTGCGCGGCCCGAGTATTGCGGTTCAAACCGCGTGCTCGTCGTCGCTCGTCGCGCTGCATCTGGCCTGCCTGAGTCTGCTGTCCGGCGAATGCGACATGGCACTGGCCGGCGGATCGTCGTTGTGCATTCCGCACCGTGTCGGTTACTGGCACTCCCCGGGATCGATGGTCTCGGCTGTTGGCCACTGTCGGCCCTTCGACGTGCGGGCCGACGGTACTGTCTTCGGCAGTGGTGTTGCGTTAGTGGCCCTCAAGCCGTTGCAGGCCGCCATCGACGCCAGCGACCGAATTCATGCCGTCATCCTCGGGTCAGCGATCAACAACGATGGATCCATGAAAATGGGTTACGCGGCGCCCAATCCTGCCGCTCAAGCCGATGTCATCGCGGAAGCTCATGCGGTGGCCGGTATTGATTCGTCGACTGTGAGCTATGTCGAGACCCATGGAACCGGTACCCCGCTCGGGGACCCCATCGAAATCCAAGGGTTGAAAACGGCATTCGAAGTGTCGCAGATACCCCGCCCGGGCCCATGTGTACTGGGGTCGGTCAAATCGAACATCGGCCACTTAGAAGTTGCCGCCGGAATCGCGGGTCTGATCAAAACGATTTTGTGCCTGAAGAACAAGGCGATTCCCGCGACGTTGCACTACACCAGTCCGAATCGGGAGCTGCGTCTGGACCAAACTCCGTTCGTCGTGCAAAGCAATTACGGCCCATGGAAGTGGGACGGCGTGCGTCGGGCAGGGGTCAGCTCGTTCGGGGTCGGTGGTACCAACGTCCACGTCGTCTTGGAAGAAGCATCAGTTGAAGCATCCACTGTTGCTGCGTCGACCGGTCCCCAGGTGATCCTTCTGTCAGCGCAAACCGCTGCGGCGCTTGGTGAATCGCGGGAAGCTCTGGCCACGGTGTTAGAAAAACCAGGCGCACCGGACCTGTCCGACGTCGCTTATACGTTGGCCGGGCGCCGAAAGCACAACATCACGATGGCTGCCGTCGTCCGTGACCGGGAGCATGCGGTCACGGTTCTGCGGGCGGCCGAGCACGACAATGTTTTCGTTGGCGAATCCGGTGCTGATACCGGGCGCAGTGCCGCCGCCTCAATCACCACCTTGGGGTCAGATCGCGTCGTTTTCCTGTTTCCCGGGCAAGGTGCTCAGCACGTTGGAATGGCCAAAGGACTCTACGACACAGAGTCCGTCTTCGCTGAACACTTCGACACCTGTTCTGCCGGATTCCGCGAAGCGATGGATGACCTGGATTTGCATTCGGCGATATTCAATGGTACCGCAATCGATCTGGAGCGCATCGACCGTTCGCAACCGGCGCTGTTCACGGTGGAATACGCACTGGCGAAGTTGGTCGAAAGCTTTGGCGTAGGTGCCGGGGCCTACATCGGATACAGCACTGGCGAGTATATCGCAGCCACCTTGGCCGGGGTATTCGACCTCGAGACGGCGATCAAAACGGTGTCGTTGCGTGCCCGTTTGATGCATGAGTCGCCGCCGGGAGCCATGGTTGCGGTGGCGCTGGGCCCCGAGGACATCACCGAGTACTTAGCAGAGTATTCTGCTAAGGGCGTCGAGTTGTCCGCCGTTAACGATCCCGGTAACTGCGTGGTCGCCGGGCCCAAAGACCAGATTCGCGCGTTCAGCCAACGTCTTGACGAGGTGGGGATACCCGTACGTCGGGTCCGTGCCACTCATGCGTTCCATACAAGCTCGATGGAGCCTATGCTGAGAGAATTCTCCGAATTCCTTTCTCGTCAACAGCTTCGCGTTCCGAACACACCGTTGCTGAGCAACCTCACCGGAACCTGGATGTCCGAGCAGCAGGTCACCGATCCGGAAAACTGGACACGTCAAATCAGTTCCACGATCCGCTTCGCCGACGAGCTAGACGTGGTGCTGTCGCAATCCGGGCGAGTCCTTGTCGAAGTTGGTCCCGGTGGCAGCTTGACCGGTTCGGCGATGCGTCACCCGAGGTGGTCGAGTGGGCACCGCGCTGTTCGGCTCATGCGCCATCCGCTTCAGAACGTTGATGACCACGACACGTTCCTGCGCGCACTGGGTGAACTCTGGTCGGCTGGAATCGAAGTTGACTGGGCGCCGCAGCGTTCGGTCATGCCGCACCTCGTTTCCTTGCCCGGATATCCGTTTGCTCGACAACGTCATTGGGTCGAACCCCGATATACGATCTGGGCGCAGATTCCCGGCGCGAGCAGTGGTTCGCCGGTTGACTCCAGCGTCGATTCCGCCACCGTTGAAGGGGTGCGAGGCGGGGAGTCGCAGACTGAGGCCACGTTGCAGCGCATCTGGTCACAGTGCTTAGGTGTCAGTTCAGTAGATCGGAATGCCAATTTCTTTGATCTAGGCGGCGACTCCTTGATGGCGATCAGCATCTCGATGGCCGCGGCCAACGAGGGTATGACCATCACACCGCAGGATATGTACGAGCACCCGACTCTGGCCTCGTTGACGGCTGCCGTCGATGCCTCATTCGCGTCGAGTGGGTTGGCGAAACCACCGGAGGCCGCGGCGCATCCGGCGGTTCCACCCAACATTGCTTACTTCCTCGAGCGGGGGTTGTGCGACACTGGCCGCTGGCGCGTTCCATTGATCCTGCGGCTTGACCCCAAGATAGGGTCAGACGACATTCGAGCCGTGCTGACCGCAGTGGTCAATCACCACGACGTCTTGCGCCTCAGCCTCGTCGACAACGACGGAATGTGGGAACAGCACATCGCGGCGACCGGAGAATTCACTCGGCTCTTGACCCAGACGCTTCCCGACGGTGTAGCCGCCGGCAGTGCAGAGGAACGGGCCGTGGTATCCAGTATTCTGGCCGAACTCATTGCTAGTCAAAGTGATTTGAACGAGCCACTGACCGCCGTGCAGATCACAACCGCTCACGGTGGTCCGCACTATCTCGGTCTTGCCGTGCACCAGATGGTTATCGACGATGCATCGCGCCAAATCTTGGGGACCGATATCATCACCGCGTTTGGGCAGCGGCTGGCCGGCGAGGAGATCACGCTGGAACCGGTCACCACTGGGTGGCGGGAATGGTCACTGCGCTGCGCGGCCCTTGCGACGCATCCGGCAGCCCTCGACACTCGCTCTTTTTGGATCGAGAATGCGAACAAGGTGAACTTGTGGTTGGCTGATGTCTCGCTCAATACAGATGTTATTCAACCGCCCGGTGCCGACGATCTGATTAGGATGCCGTGCACGCTAAGCGTTGAGCAGACGTCCGAGCTGGATGATGCCCGGCGTAGGTTTCGCCGATCGATTCAGGCGATCGTGCTGGCCGCGCTTGGTCGCACAATTGCCCAAACGGTCGGTGATGGTGTGGTCGCCGTAGAGCTTGAGGGCGAGGGCCGTTCGGTGTTGCGGCCGGACGTCGACGTGCGCAGAACAATCGGTTGGTTCACGAACTATTACCCAATTCCGCTGGTCTGCGTGAAGGGCCAGGGCGCGCTTGCGCAACTAGACGCTGTTCATAACACCCTTAAATCCATTCCGCATTACGGAATTGGATACGGATTGCTGCGGTATATGTACGCGCCGACCGGACGTGTATTCAGTGCGCAGCGCACGCCTGACATTCACTTTCGGTACGTGGGCGTTGTCCCTGAGCCGCCATCCGTCGATGCTACGGTACAGTTCGACTCGGACATGACGATTCCGGTGCAAGAACCGGTTCCTGGGATGGGCCACGCCATCGAACTTCGGACGTATCGGTTTGGTGGTTCACTGCATCTAGATTGGTGGTACGACATCCGGCGGATTCCGCAGGTAACAGCAGAAGCACTCGCGCAGTCCTTCCCGGTCACGCTTAGCAAGTTGATCCAGGAAGGCATAGCTACGCAAAAGGATGCGCACGACGAGAGTGAAATGGCTGGGGCACCCCAAGCGGGCGTTCTGGTGGACCTGTCAACCCTGGATGC

Protein Sequence 

>ML2353c_PpsE_protein
ETSDYPRQRDRGGRHGRQISGRQRCVGVLDQPSARQGVDRHPV_ARAARQRGQRQSTGRSGVCASRTVTRRDRRV_C_LLRSAAAGRAGIGSTTPVVPSVRVACARGCRL_PRAVRRLDRSIRNQFSQRLSLA_PVVASRPPHRFG_GTQLRPVQSVPTERQRLLGNSDIARVQLARPEYCGSNRVLVVARRAASGLPESAVRRMRHGTGRRIVVVHSAPCRLLALPGIDGLGCWPLSALRRAGRRYCLRQWCCVSGPQAVAGRHRRQRPNSCRHPRVSDQQRWIHENGLRGAQSCRSSRCHRGSSCGGRY_FVDCELCRDPWNRYPARGPHRNPRVENGIRSVADTPPGPMCTGVGQIEHRPLRSCRRNRGSDQNDFVPEEQGDSRDVALHQSESGAASGPNSVRRAKQLRPMEVGRRASGRGQLVRGRWYQRPRRLGRSIS_SIHCCCVDRSPGDPSVSANRCGAW_IAGSSGHGVRKTRRTGPVRRRLYVGRAPKAQHHDGCRRP_PGACGHGSAGGRARQCFRWRIRC_YRAQCRRLNHHLGVRSRRFPVSRARCSARWNGQRTLRHRVRLR_TLRHLFCRIPRSDG_PGFAFGDIQWYRNRSGAHRPFATGAVHGGIRTGEVGRKLWRRCRGLHRIQHWRVYRSHLGRGIRPRDGDQNGVVACPFDA_VAAGSHGCGGAGPRGHHRVLSRVFC_GRRVVRR_RSR_LRGRRAQRPDSRVQPTS_RGGDTRTSGPCHSCVPYKLDGAYAERILRIPFSSTASRSEHTVAEQPHRNLDVRAAGHRSGKLDTSNQFHDPLRRRARRGAVAIRASPCRSWSRWQLDRFGDASPEVVEWAPRCSAHAPSASER__PRHVPARTG_TLVGWNRS_LGAAAFGHAAPRFLARISVCSTTSLGRTPIYDLGADSRREQWFAG_LQRRFRHR_RGARRGVAD_GHVAAHLVTVLRCQFSRSECQFL_SRRRLLDGDQHLDGRGQRGYDHHTAGYVRAPDSGLVDGCRRCLIRVEWVGETTGGRGASGGSTQHCLLPRAGVVRHWPLARSIDPAA_PQDRVRRHSSRADRSGQSPRRLAPQPRRQRRNVGTAHRGDRRIHSALDPDASRRCSRRQCRGTGRGIQYSGRTHC_SK_FERATDRRADHNRSRWSALSRSCRAPDGYRRCIAPNLGDRYHHRVWAAAGRRGDHAGTGHHWVAGMVTALRGPCDASGSPRHSLFLDRECEQGELVVG_CLAQYRCYSTARCRRSD_DAVHAKR_ADVRAG_CPA_VSPIDSGDRAGRAWSHNCPNGR_WCGRRRA_GRGPFGVAAGRRRAQNNRLVHELLPNSAGLREGPGRACATRRCS_HP_IHSALRNWIRIAAVYVRADRTCIQCAAHA_HSLSVRGRCP_AAIRRCYGTVRLGHDDSGARTGSWDGPRHRTSDVSVWWFTASRLVVRHPADSAGNSRSTRAVLPGHA_QVDPGRHSYAKGCARRE_NGWGTPSGRSGGPVNPGC

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PpsE with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

45 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PpsE

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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