ppsD
mL2354c
PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2799411 – 2804879
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2354c_ppsD_dna
GCGAGTCATGACGAGCTTGGCAGAGCGTGCGGCGCAGCTGTCGCCGAACGCGCGCGCGGCACTGGCACGCGAACTTGTCCGTACCGGGACTGCTTTCCCAACCGACATTTCAGAGCCAGTCGCGGTGGTGGGCATCGGATGTCGTTTCCCGGGGAATGTAACTGGCCCGGATAGTTTTTGGCAGCTGTTGGTCGATGGCGGGGACGCGATCAGCGAAGTTCCGCCAGATCGGTGGGATGCGGATGCGTTCTACGATCCCGACCCGTCGGCGTCAGGGCGGATGACGACGAAATGGGGCGGCTTCGTTCCCGACGTTGATGCTTTCGACGCCGAGTTCTTTGGCATCACACCTCGCGAAGCCGTGGCGATGGATCCGCAGCATCGGATGCTGCTCGAGGTTGCCTGGGAATCCCTTGAGCACGCCGGCATTGCACCGGATTCGCTGAGCGGCACTCGAACTGCGGTGATGATGGGACTTTCCTCGTGGGACTACACGATCGTCAACATCGAGCGCAGAGCCGATATCGATGCCTACCTGAGCACCGGAACTCCGCATTGCGCGGCAGTAGGACGGATCTCGTATTTGTTAGGATTGCGTGGTCCGGCGATGGCCGTGGACACTGCGTGCTCGTCGTCGCTGGTGGCAATCCACCTGGCTTGTCAGAGCTTACGGTTGCGTGAGAGTGACGTGGCATTAGCCGGCGGTGTGCAGCTCATCTTGTCGCCTTTCACCGCCATCGCGTTGTCCAAGTGGTCGGCGTTATCACCGACCGGACGATGCAATAGTTTCGATGCCAATGCGGATGGATTCGTGCGTGGCGAAGGTTGCGGAGTAGTGGTGCTAAAACGGCTAGTTGACGCGCTGCGCGACCAGGATCGTGTGCTGGCTGTGGTTCGTGGTTCGGCGACCAATCAAGACGGTCGGTCCAACGGCATGACCGCGCCTAACGCGCTGGCGCAGCGCGACGTTATTACTACCGCCTTGCGGCTCGCGGATATCACCCCAGACAGCGTTAACTATGTTGAAACACATGGAACCGGAACAGTGTTGGGAGACCCTATCGAGTTCGAATCGCTGGCTGCCACTTACGGCCGCGGCGAAAGCTCCTGTGCTTTGGGGTCGGTCAAGACCAACATCGGCCATCTAGAGGCTGCCGCCGGAGTGGCCGGATTCATCAAGACGGTGCTGGCGTTGCAGCACGCGTACATTCCGCGTAATGTCCACTTTACTCAATGGAACCCGGCCATCGACGCATCCACGACTCGGCTGTTTGTGCCCACTGAGAGCGCACCATGGCCGGCAATTCCGGGCCCGCGTCGTGGAGCGGTGTCATCGTTCGGGCTCAGTGGGACTAACGCCCATGTAGTGATTGAGCAGGCGCCAGACACGACTGTACCTATATCGGCAGCTGTTGGTAGGCAGTATGTTTCGGCTCTGGTGGTGTCGGGTAAGACTGTTACGCGGGTGGCGTCGGCAGCCGCAGTGTTGGCTGACTGGATGTCGGGACCGGGCGCGGCGGCACCACTCGCCGACGTGGCGTACACGCTGAACCAGCACCGGGTTCGGCACCCCAAGTTGGCAACCGTGATTGCGCGTGATCACGCGGATGCCGTTGCGGGGTTACGGGCGCTGGCGGCCGGACAGCCACGAGTGGGAGTGGTGGGTTGTGATCAGCATGCAGCTGGGCCCGGTCGAGTTTTTGTGTATTCGGGTCAGGGCTCGCAGTGGGCCGGGATGGGTAGGCAGCTGCTGGTCGATGAGCCGGCCTTCGCCAAGGCGGTAGCTGAACTGGAGCCCACGTTCGTTGCTCAGGTAGGTTTTTCGCTGGAGCATACACTCGCCTATGGCGACGAGGTGGTAGGTATCGAACGCATTCAGCCGGTGCTGGTGGGGATCCAGCTGGCGCTCACCGAGTTGTGGCGTTCTTACGGGGTGACTCCGGATGCTGTGATTGGGCACTCGATGGGTGAGGTGTCCGCGGCAGTGGTAGCCGGCGCGTTGACGCCCGAGCAGGGCTTGCGGGTGATCGCTACCCGGTCCCGGCTGATGGCGCGTCTGTCGGGTCAGGGCGCGATGGCATTGCTAGAGTTGGACGCCGACGCCGCCGAGGCTCTGATTGCTGACTACCCTGAGGTGACGTTGGCAGTGTACGCTTCGCCACGCCAATCGGTGATTGCCGGCTTGCCGGAGTCGGTGGATGCGGTGATATCGGTGGTGGCGGAGCAGAATCGGTTAGCGCGCCGCGTCGATGTCGAGGTGGCTTCGCACCATTCGATCATAGATCCGATTCTGCCCGAGTTGCGAAATGCGCTAGCGGATTTGGTTCCGCAGACGCCGATCATCCCGATAATCACCACCACTCACGAACACACCCAGGCGGTGATGGACGCCGACTATTGGGCGGCTAACCTGCGCAACCCGGTGCGATTCCACCAGGCCATCGCACAGGCTGTTAGCGGCGTCGGTGGATTCAATCGTACCTGCCACTCTTTCATCGAGATCAGCCCCCACCCCGTGCTCACACACGCTATCACTGACACCGTCGGCGGGTCCGGAGGCCATGTTGTCACGTCGGCGATGAACCGCGACCTCGACCAGACCCTGTTCTTCCACGCCCAACTTGCCACCGTCGGGGTGACCGAGTCGGATAGCGCCAAGGGTCGATTGGTGGACCTGCCACCCACGCCGTGGCAACATTCGCGATTCTGGGTTGCGGATCGATCAGCGATGTCGGAGCTGGCCGTGGCCCACCCGTTGCTCGGTGTGCATGTCGAAATGCCCGGCAGTGGAGACCACGGCTGGCAGGCAGATGTCGGAACCGACGTATGTCCCTGGCTAGCTGACCATAAGGTATTCGGCCAGCCTATTATGCCGGCTGCTGCGTTTGCTGAGATCGCTGTGGCGGCGGCCAGCGAAGCGCTCGGTGTACCCGCTGGCACTTCTGGGGCCAATATTGTAATCCACCAGTTCGAGGTCGAGCAAATGCTTTCCCTCGACAACCACACACCGCTCACGACGCAGTTGACCTATCACGGGAACAGCAAAATTCGGGTCGAGATCTATTCTCGCTCACCTCGCGGTGATTTCTCTCGGCACGCCACGGCCAATGTTGAGCATGTATCGCACAATGCCGTGCAGCCGTTCCAGCAAGCACCCGGTTCTTCGAACGGGGTAACCGTGTCTCCAGCCGATTTCTACGCTGTGCTACGGCAGACTGGTCAACACCATGGCCCGGTGTTTGCTGTCTTGACCCGGATAACTCGGCTGCTTGACGGTTCCGCGGAAACCGAGATCACTCTTCCCGACGAGGTTCCCCGGCATCCCGGATATCGACTCCATCCCGTTGTACTAGATGCGGCATTGCAAAGCGTCGGTGCCGCAATACCTGACGGTGAGGTCGCTGAGTCGGCGGAAGTCAGCTACCTGCCGGTGTCGTTCGAGGCGATCCGAGTGTACCGCGACATCGGTCGGCACGCCCTGTGTCGGGCACGTTTGACCAACCTCGACGGGGGTACCGGCAAGTTGGGCAAGATCGTCTTGATTGACGACGCTGGTTACGTAGCAGCCGAAGTGGATGGCATTTACTTGCGACGTATTGAACGCCGTGTGGTGCCATTACCGTTGGCGCAGAAGATCTTCGACGCTGAGTGGATCGAAAGCCCGATCCCGGCTTCGCGAGCTTTGGAGCAGATTACCGAGACAGCGCGCGCAAGTTGGTTGGTACTTACCGACTGGGATCCTTCGATCAAATCCCTGACAGACGAATTCATTGCGAGATGGCGCTCACCAATGCGACGGGTGTACACTGCAAATCTCCACGACGAATCGGCGATGCTTGCCGCATTCGCAGAGACGGCGGGTGATCCAGAGCACCCACCTATTGGCGTGGTCATCTTCGTCGGCGGTGCGGCAACCGGGCTGGACGATGGGCTGGTGCAAGCGCGAGACTCGGTGTGGTCGATCTCGACTGTCGTTCGTGCGATCGTAAGTACGTGGCATGGCCGATCGCCACGGCTGTGGTTGATCGCCGGTGGTGGTCTTTCCGTTCAGGATGACGAGCTGGGGGCTCCCGCGACGGCTGCTTTGAAGGGCCTGGTGCGAGTGCTGGCCCTGGAGAATCCGGACCTGCGCGCCACCCTGCTCGATCTGGATGCCACGCAAGATCAGATCGCAGCACTGACTGCAGAATTGCACAATTCTGCGAGCGAGTTCGGTGGCGATGATGTGATCGCGTGGCGGGGTCAACACAGATTCGTCGAACGGCTGTGTAAGGCCACATTGGATGCTGGCAAAGACAATCCTGTGGTTCGCCCCGGAGCGGCATACATCGTGACGGGTGGTCTTGGTGGCCTTGGCTTAGTCGTTGCCAGATGGTTGGTAGATCGCGGTGCCGGCCGGGTGGTCCTGGGCAGCCGCAGCGACCCCACCGAGGAGCAGCGCAAAACTCTGGTCGAATTGGAAGCTCGTGCCGAAATTGTGTTTTTGCGCGGCGATGTGACGTCGCCAGGTGTGGCCGAGAGTCTGGTCGCGGCGGCAGGACGAGCGGGCGGCCAGTTGCGCGGCATCGTGCACGGTGCGGCGGTCATCGAAGACAGTCTGGTGTTCACCATGACCAGAGAAAACTTGGAGCGAGTTTGGGCGCCTAAGGCCACTGGCGCGCTGCGGATGCACCAGGCCAGCGTTAGCTGCGAGCTCGACTGGTGGTTGGGGTTTTCCTCTGTTGCTTCGCTCTTGGGCTCGCCCGGACAAGCGGCATATGCATGTGCCAGTGCATGGCTCGACGCTCTGGTCATGTGGCGCAAGGCATCCGGTTTGCCATCGGCGGTGATCAACTGGGGTCCGTGGTCAGATGTGGGTGTCGCCCAGGCTTTGGTAGGCAGTGTTCTAGATACAATCACTCCGGCAGAGGGCATCGAGGCTATCGACTCGTTGCTGGCTGCCGGTCGGACTCGCACGGGCGTTGCCCGGTTACGTGCCGATAAGGCTCTGGTCGCATTCCCGGAGATGCGTAGCATCAGCTACTTCACCTGGGTGGTCGAGCAGCTGGCCGCGGCGGGTGACCTGGGTGACTGGGTCGGGTCCGACACGCTTGCCGATCTCGATCCGGCAGAGGCCCAGCGCGTGGTGACCGAGCGGATGTGCGCGCTTATCGCGGCGGTTATGGGTTACGCTGACCGATCAACAGTTAATCCTGCTGTGCCGTTGACCGAGCTGGGGCTGGACTCCCTGATGGCGGTGCGGATCCGTAACGGTGCACGGGCGGACTTCGGCGTGGAGCCGCCGGTGACATTGATTTTGCAGGGCGCGTCCCTGCAAGACTTGACCGCCGATGTTGTGCGTCAACTTGGGCTCGCGGGCCCAAAGCAGGCGCTCGAGAACGCTGACACCGTTCGCGACCGCGTTCAGCAGCGTGCGGCGGTGCGACGTGGAGCCGTGATGCGGCGCCGACCTAAACCTGACGTACAGGG

Protein Sequence 

>ML2354c_PpsD_protein
ASHDELGRACGAAVAERARGTGTRTCPYRDCFPNRHFRASRGGGHRMSFPGECNWPG_FLAAVGRWRGRDQRSSARSVGCGCVLRSRPVGVRADDDEMGRLRSRR_CFRRRVLWHHTSRSRGDGSAASDAARGCLGIP_ARRHCTGFAERHSNCGDDGTFLVGLHDRQHRAQSRYRCLPEHRNSALRGSRTDLVFVRIAWSGDGRGHCVLVVAGGNPPGLSELTVA_E_RGISRRCAAHLVAFHRHRVVQVVGVITDRTMQ_FRCQCGWIRAWRRLRSSGAKTAS_RAARPGSCAGCGSWFGDQSRRSVQRHDRA_RAGAARRYYYRLAARGYHPRQR_LC_NTWNRNSVGRPYRVRIAGCHLRPRRKLLCFGVGQDQHRPSRGCRRSGRIHQDGAGVAARVHSA_CPLYSMEPGHRRIHDSAVCAH_ERTMAGNSGPASWSGVIVRAQWD_RPCSD_AGARHDCTYIGSCW_AVCFGSGGVG_DCYAGGVGSRSVG_LDVGTGRGGTTRRRGVHAEPAPGSAPQVGNRDCA_SRGCRCGVTGAGGRTATSGSGGL_SACSWARSSFCVFGSGLAVGRDG_AAAGR_AGLRQGGS_TGAHVRCSGRFFAGAYTRLWRRGGRYRTHSAGAGGDPAGAHRVVAFLRGDSGCCDWALDG_GVRGSGSRRVDARAGLAGDRYPVPADGASVGSGRDGIARVGRRRRRGSDC_LP_GDVGSVRFATPIGDCRLAGVGGCGDIGGGGAESVSAPRRCRGGFAPFDHRSDSARVAKCASGFGSADADHPDNHHHSRTHPGGDGRRLLGG_PAQPGAIPPGHRTGC_RRRWIQSYLPLFHRDQPPPRAHTRYH_HRRRVRRPCCHVGDEPRPRPDPVLPRPTCHRRGDRVG_RQGSIGGPATHAVATFAILGCGSISDVGAGRGPPVARCACRNARQWRPRLAGRCRNRRMSLAS_P_GIRPAYYAGCCVC_DRCGGGQRSARCTRWHFWGQYCNPPVRGRANAFPRQPHTAHDAVDLSREQQNSGRDLFSLTSR_FLSARHGQC_ACIAQCRAAVPASTRFFERGNRVSSRFLRCATADWSTPWPGVCCLDPDNSAA_RFRGNRDHSSRRGSPASRISTPSRCTRCGIAKRRCRNT_R_GR_VGGSQLPAGVVRGDPSVPRHRSARPVSGTFDQPRRGYRQVGQDRLD_RRWLRSSRSGWHLLATY_TPCGAITVGAEDLRR_VDRKPDPGFASFGADYRDSARKLVGTYRLGSFDQIPDRRIHCEMALTNATGVHCKSPRRIGDACRIRRDGG_SRAPTYWRGHLRRRCGNRAGRWAGASARLGVVDLDCRSCDRKYVAWPIATAVVDRRWWSFRSG_RAGGSRDGCFEGPGASAGPGESGPARHPARSGCHARSDRSTDCRIAQFCERVRWR_CDRVAGSTQIRRTAV_GHIGCWQRQSCGSPRSGIHRDGWSWWPWLSRCQMVGRSRCRPGGPGQPQRPHRGAAQNSGRIGSSCRNCVFARRCDVARCGRESGRGGRTSGRPVARHRARCGGHRRQSGVHHDQRKLGASLGA_GHWRAADAPGQR_LRARLVVGVFLCCFALGLARTSGICMCQCMARRSGHVAQGIRFAIGGDQLGSVVRCGCRPGFGRQCSRYNHSGRGHRGYRLVAGCRSDSHGRCPVTCR_GSGRIPGDA_HQLLHLGGRAAGRGG_PG_LGRVRHACRSRSGRGPARGDRADVRAYRGGYGLR_PINS_SCCAVDRAGAGLPDGGADP_RCTGGLRRGAAGDIDFAGRVPARLDRRCCASTWARGPKAGARER_HRSRPRSAACGGATWSRDAAPT_T_RTG

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PpsD with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

11 show intermediate predicted evidence for PPIs

22 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PpsD

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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