ppsB
mL2356c
PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2811478 – 2816100
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2356c_ppsB_dna
GGTGTAAATGCGGACCGCTTTCAGCCGGATTTCCGGCATGACCACGCAGCAGCGCGCGGCTCTTATCGAAGAATTCACCAAGCTCTCTCGGATTGCTGTGGCAGAGCCCATCGCGGTAGTGGGGATCGGTTGCCGGTTTCCTGGGGACGTGACCGGGCCGGATAGCTTCTGGGATCTGCTGATCGACGGCCGCAACGCGATCTCGAGAGTGCCGGCTGATCGTTGGGACGCGGATGCGTTTTATGACCCCGACCCGTTGACGCCGGGTCGGATGACCACGAAATGGGGCGGTTTCGTCTCCGATATCGCGGGTTTCGACGCGGCATTCTTCGGTATCACGCCACGCGAAGCTGCAGCGATGGACCCGCAGCAGCGGATACTACTCGAGGTTGCCTGGGAAGCTCTCGAAAATGCTGGAATTCCACCGGATTCCCTGGGTAATAGCCGAACCGGCGTGATGATTGGCGTCTACTTCAACGAATACCAATCCATGTTGGCCTCCAGTCTGGAGAATGTAGACGCCTACAGCGGAACCGGAAACGCTCACAGCATCACTGTAGGCCGAATCTCCTACCTGTTGGGGCTGCGTGGTCCATCGGTGGCGGTTGATACAGCGTGCTCGTCGTCGCTGGTGGCGGTGCACCTAGCTTGCCAAAGTTTGCGGCTACGCGAAACTGACCTGGTCCTCGCCGGCGGAGTGAGCATCACGCTGCGCCCGGAGACGCAAATCGCAATTTCTGCATGGGGATTGTTGTCTCCGCACGGCAGGTGTGCGGCGTTCGATGCTGCGGCGGACGGGTTTGTGCGCGGTGAAGGTGCTGGCGTAGTGGTGCTTAAACGGTTGACCGATGCGGTTCGTGACGGAGATCTGGTGTTGGCGGTGGTGCGCGGTTCTGCTGTCAATCAGGATGGCCGCTCCAACGGCGTTACCGCTCCGAATACGGCGGCGCAGTGTGATGTGATCACCGATGCCTTGCGCTCTAGTGACGTTGCGCCCGAAAGCGTGAACTACGTCGAATCCCATGGCACCGGTACCGTCCTGGGTGACCCAATCGAATTCGAGGCGCTGGCGGCCACGTATGGCCGCGGTGAGAGCGCATGTGCGCTGGGGGCTGTTAAGACTAACCTGGGTCACTTGGAGGCTGCTGCGGGCATCGCCGGCTTCATCAAGACAGTGTTGGCGGTGCAGCGTGGCCAGATTCCACCGAATCTGCATTTTTCGCAATGGAATCCGGCTATCGACGCTGCATCGACTAGATTCTTCGTCCCCACTGAGAACTCCTCGTGGCCGATCTCGGACGGTCAAGCAGGGCCGCGGCGCGCGGCGGTGTCATCGTTTGGCCTCGGTGGGACGAACGCGCATGTTGTCATTGAGCAGGGTCCTGAGCTGACACCGGTCACAGAATGCAGTTCCAACACTGCGGTGTCGACGTTGGTGGTGACGGGTAAGACGGCGTCGCGGGTGGCAGCGATGGCGGGGATGCTGGCCGATTGGGTTGAGGGGCCCGGTGCTGAAGTGGCGTTGGCTGATGTGGCCCATACATTGAATCATCACCGGTCGCGGCACGCCAAGTTCGGCACCGTGGTTGCCCGTGATCGGATCCAGGCAGTGGCTGGATTGCGGGCGTTGGCCGCCGGCAAACAGGCGCCCGGTGTGGTCGGGCAGCAGGATGGCACACCTGGGTCAGGAACGGTGTTTGTGTACTCGGGACGTGGTTCGCAGTGGGCGGGGATGGGGCGTCAATTGCTGGCCGATGAACCGGCTTTCACGGCCGCGGTTGCCGAGTTGGAACCGGTGTTTGTTGTCCACGCCGGTTTCTCGTTGCACGATGTGCTCGCTAATGGCAAAGAACTGGTTGGTATCGAGCAGATCCAGCTGGGGTTAATCGGCATGCAACTGACGCTGACTGAGTTGTGGCGTTCCTATGGGGTGCAACCTGATTTGGTGATCGGGCATTCGCTGGGTGAGGTGGCCGCCGCCGTGGTGGCTGGGGCGCTTACCGCCGCTGAGGGGCTGCGGGTGACAGCCACTCGGTCGCGGCTGATGGCCCCGCTGTCTGGGCAGGGCGGTATGGCACTGCTCGAACTCGACGCGGTCGAGACGGAGGCGTTGATTGTCGACTACTCGCAGGTGACATTGGCGATTTACAATTCGCCGCGCCAAACGGTGATTGCCGGGCCCACTGAACAGATCGATGAGTTGATTGACCGGGTGCGCGCGCAGAATCGGTTTGCCAGTCGGGTCAATATTGAAGTGGCCCCCCACAATCCGGCGATGGATGCGCTGCAGCCGCAGATGCGTTCCGAGCTCGCCGATGTGGCCCCACGGACTCCGACGATTCCGATCCTTTCCACCACCTATGCTGACCTTGGCTCGTGCCCGGTGTTCGATGCCCAGCACTGGGCCACCAACATGCGCAACCCAGTGCATTTCCAGCAGGCCATCATGACCGCTGGAACTGACCACCGCACTTTCATCGAAATCAGTGCACACCCGCTGCTGACCCAAGCCATTACTGACACCCTGCACGGTACCCGGTGCATCAGCATTGGGACCCTGCAACGCGATGCCGACGACACCGTCACCTTTCACACCAACCTCAACAACGTCCACACCGTCCACCCACCACACACCCCTCATCCTGCGGAACCACACGTAACTATCCCCAGCACTCCCTGGCAGCACACCCGCCACTGGATCACCACACCGCTGGCAAGCACGACCGCGCTGCAACATCTCGACCGCAACAGGGTTACGACGCACGCTACCGGAATTGGAAACACGGAACTCGATGACTGGATCTACCAGCTTGACTGGCCGACTCGGCCCCTGACAAGTGAGCCTGGTGCGACGTGGGCCAGCAGCGGCTCGTGGCTGGTGGTGTCCGATGCCGGACTGTCGGATGAACTGGCTCGGTTGGTGGTATTGGCCGATCCTGCATCCCGGGTTGAGTACCTCGCACCTTCGGCGCTTGATCATGATGTGAGCACGCTGCATGACCTGCATAACGCTTTACGGGGTGTCGATAACGTACTCTATGCACCATCGGTCTCGACCGAATCTGTCGACCCTGTCGATCCGGAGTCCGGGTACCGGCTGTTCCATGCGGTGCGACGGTTGGCGGCCGCGATGGTTGCGGGTACTTCGAAACCGAAACTCGTCGTCGTGACTCGCAATGCTCAACCCGTTGCAGTGGGTGAGCGCGCCAACCCCGCCCACGCGGTGTTGTGGGGCTTTGGCCGAACATTGGCGCTGGAACATCCCGAAATTTGGGGTAGTGTCATCGATCTCGATGCGTCGATGCCTCCCGAGTTGGCTGCCCGGTGCATATTGGACGAAGTCGCTAGCCAGGACGAAAAAGACCGAGAGGACCAGGTCGTCTACCGAGCGTGTCTACGTCGCGCACCACGGCTGCAAAGGCGAACTGCATCCGCGGTGTCGTCGGTGAAGTTGAGTTCGGGGCAAGATACCACTCAGCTCGTCATCGGGGCCACCGGAAATATCGGACCGCATCTGATCCGTCAGCTCGCCGCGATGGGGGCCACGACGATCGTCGCCGTGTCTCGCAATCCCAGCACCCGGCTGTTAGAGCTGGATAAGAACCTCGCCGCAACCGGGACGAACCTCATCTCGGTTGCGGCGGATGCGACCGACCCTACCGCGATGACTGCGTTGTTCGATCGTTTTGGAGTGGATCTGCCTCCGCTAGAGGGAATCTACTTAGCGGCTTTTGCTGGCCGTCCGGTCTTGCTGAGCGACATGACTGATAACGACGTGGTCGCGATGTTCCGACCCAAACTGGACGTCGCATCGCTGTTGCACCGTTTGTCGCTGAAACAGCCTGTAAAATACTTTCTTTTGTTCTCCTCGATCTCAGGTCTTATCGGTTCACGATGGCTGGCGCATTACACCGCGACCAGTGCTTTCCTGGACATTCTGGGCTACGCCCGGCGGCTGGTAGGATTGCCTGCCACTGTCGTGGCCTGGGGCTTGTGGAAATCGCTGGCCGACGCGCAGCAAGACGCGACCCAGGTAAGCGCTGAATCCGGCCTGCAACCCATGACTGACGACGTAGCGATCGGGGCATTGCCGTTGGTGATGAGCCCGGACGCGCCAGTGCATTCGGTTGTGGCGGCAGCGGATTGGCCGCTACTGGCCGCTGCATACCAGACCCGCGGGGTGCTGCGCATGGTCGATGACCTGCTGCCCGCACCGGGCGAGGTACTGATGCAGGAAAGTGAATTCCGCAAAGCCCTACGGACTTGCCAGGCAGAACGCCGACATAACATGTTGTTCGACCACGTTAGTGCTCTGGTCGCCAAGGCGATGGGACTGCTTCCCGCTGAAACACTCGACCCGTCGGCTGGCTTCTTCCAACTAGGCATGGACTCGCTGATGAGCGTGACGTTGCAGAGAGCCTTGTCGGACAGCCTTGGCGAGTTTCTGCCGGCGTCTGTCGTTTTTGACTACCCGACCGTGTACAGTCTTACCGATTATCTGGCCACTATACTGCCTGAATTTCTGGAACCAGAAGCACCATCTGGGCGGACAACGGCCGACGCATATGACGAATTCACTGAATCCGAGTTGTTGGATCAACTTTCGGAAAGACTAAGAGGAAC

Protein Sequence 

>ML2356c_PpsB_protein
GVNADRFQPDFRHDHAAARGSYRRIHQALSDCCGRAHRGSGDRLPVSWGRDRAG_LLGSADRRPQRDLESAG_SLGRGCVL_PRPVDAGSDDHEMGRFRLRYRGFRRGILRYHATRSCSDGPAAADTTRGCLGSSRKCWNSTGFPG__PNRRDDWRLLQRIPIHVGLQSGECRRLQRNRKRSQHHCRPNLLPVGAAWSIGGG_YSVLVVAGGGAPSLPKFAATRN_PGPRRRSEHHAAPGDANRNFCMGIVVSARQVCGVRCCGGRVCAR_RCWRSGA_TVDRCGS_RRSGVGGGARFCCQSGWPLQRRYRSEYGGAV_CDHRCLAL__RCARKRELRRIPWHRYRPG_PNRIRGAGGHVWPR_ERMCAGGC_D_PGSLGGCCGHRRLHQDSVGGAAWPDSTESAFFAMESGYRRCID_ILRPH_ELLVADLGRSSRAAARGGVIVWPRWDERACCH_AGS_ADTGHRMQFQHCGVDVGGDG_DGVAGGSDGGDAGRLG_GARC_SGVG_CGPYIESSPVAARQVRHRGCP_SDPGSGWIAGVGRRQTGARCGRAAGWHTWVRNGVCVLGTWFAVGGDGASIAGR_TGFHGRGCRVGTGVCCPRRFLVARCAR_WQRTGWYRADPAGVNRHATDAD_VVAFLWGAT_FGDRAFAG_GGRRRGGWGAYRR_GAAGDSHSVAADGPAVWAGRYGTARTRRGRDGGVDCRLLAGDIGDLQFAAPNGDCRAH_TDR_VD_PGARAESVCQSGQY_SGPPQSGDGCAAAADAFRARRCGPTDSDDSDPFHHLC_PWLVPGVRCPALGHQHAQPSAFPAGHHDRWN_PPHFHRNQCTPAADPSHY_HPARYPVHQHWDPATRCRRHRHLSHQPQQRPHRPPTTHPSSCGTTRNYPQHSLAAHPPLDHHTAGKHDRAATSRPQQGYDARYRNWKHGTR_LDLPA_LADSAPDK_AWCDVGQQRLVAGGVRCRTVG_TGSVGGIGRSCIPG_VPRTFGA_S_CEHAA_PA_RFTGCR_RTLCTIGLDRICRPCRSGVRVPAVPCGATVGGRDGCGYFETETRRRDSQCSTRCSG_ARQPRPRGVVGLWPNIGAGTSRNLG_CHRSRCVDASRVGCPVHIGRSR_PGRKRPRGPGRLPSVSTSRTTAAKANCIRGVVGEVEFGARYHSARHRGHRKYRTASDPSARRDGGHDDRRRVSQSQHPAVRAG_EPRRNRDEPHLGCGGCDRPYRDDCVVRSFWSGSASARGNLLSGFCWPSGLAERHD__RRGRDVPTQTGRRIAVAPFVAETACKILSFVLLDLRSYRFTMAGALHRDQCFPGHSGLRPAAGRIACHCRGLGLVEIAGRRAARRDPGKR_IRPATHD_RRSDRGIAVGDEPGRASAFGCGGSGLAATGRCIPDPRGAAHGR_PAARTGRGTDAGK_IPQSPTDLPGRTPT_HVVRPR_CSGRQGDGTASR_NTRPVGWLLPTRHGLADERDVAESLVGQPWRVSAGVCRF_LPDRVQSYRLSGHYTA_ISGTRSTIWADNGRRI_RIH_IRVVGSTFGKTKRN

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PpsB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

11 show intermediate predicted evidence for PPIs

33 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PpsB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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