fadD26
mL2358c
FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2821713 – 2823464
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2358c_fadD26_dna
GTGTGGTATGGTCGTAACCAACTTTTCCGTCCCCGCTTTGCTGAAAGAACGGGCGGATCAGCAGGCTGACACTACCGCCTACACATACATCGACTACGGGTCGGACCCGAAGGGTTTTGTTGAGAGCTTGACGTGGTCGCAAGTTTATATGCGTTCATGCGTCCTTGCTGACGAACTCAAATTGTGTGGTGTGCCCGGTGATCGAGTTGCAATTTTGGCGCCACAGGGACTGGAATATATTATCGCGTTCTTAGGGGCTCTTCAGGCCGGATTTATCGCGGTACCTCTTTCGCCACCGCAGTATGCGATTCACGACGAACGCGTTTCGGCGGTGTTACGGGATTCTCAACCGATCGCTATTCTTACAACTTCATTTGTGGTTAGTGACGTGGCGAAATACGCATGTGAACAAGATGGGTGGAACGCTCCGTCTGTCATTGAGATCGATCTGCTTGACTTGAACGCGTCACTCCCGCTTCCAAAAGTCCCCCAGCCTTTTACTAGCCCGGCTTACCTCCAATACACATCCGGGTCGACACGTACGCCAGCCGGTGTTATGGTGTCGCATAAGAACGTTATCGCTAACGTGCAGCAAAGCATGAACGGCTATTTCGGCGATGCCGCAAAAACTCTGAACACGACCGTGGTGTCATGGCTTCCCTTGTTTCACGACATGGGCTTGATTCTTGGGGTCTGTGCTCCAATGGTCGCGGGGCGAAGCTCGGTGTTGTTGAGCCCTATGTCATTTTTGCGGCGCCCCGCCTGTTGGATGCAACTTCTTGCCACTACCCAGGCGTGTTTTTCTGCGGCACCGAATTTTGCCTTTGAGCTGGCCGTACGCAGAACGTCCGACGACGACATGAACGGACTCGACCTCGGGGATGTGGCCGGAATCATCAGCGGCAGCGAACGAGTCCATATCGCAACGGTGAAACGTTTCACCGAGCGCTTCGCTCGGTTCAATCTCAGCCCCTCGGTGGTACGACCCTCGTACGGGCTTGCGGAAGCGACCGTGTACGTGGCGGCTCCGGAACCTGGCACCGCACCTAAGGCGGTTCGTTTTGACTACGAATACCTGACGGCCAGTAAGGCTAAGGCCCGCCGAGCCGAAGGGAGTGTCGCGACCGAACTAATTAGTTATGGCTCCCCTGATGCATCGGCTGTGCGAATCGTCGATCCGGAGTCCATGATCGAGAACCCTGCTGGAATGGTTGGGGAGATCTGGGTACAGGGCGACCACGTTGCCATGGGGTATTGGCGGAAGCCCGAGCAGACTGCACGTACGTTCAATGCAAAGATTGTCAACCCCGCGCCTGGCACTTCGGAAGGTCCGTGGCTGCGGACCGGAGATCTGGGTGTTATGTCAGACGGCGAACTGTTCATCATGGGCCGCATCAAAGACTTGCTCATTGTCGATGGTCGCAACCACTACCCGGACGACATCGAAGCGACAATCCAGGAGATCACCGGCGGTCGGGTCGCGGCGATCACTGTGCCGGACGACCTCACCGAGCAGTTGGTGGCGATCATTGAATACAAGGAACATGGAGCGTCCGCGGAAGACCACATGCACAAAGTCCATTCGGTGAAGCGTGAAGTCACATCCGCTATATCGAAGTTACATAGTTTGCATGTGGCCGACCTCGTTCTGGTGTCACCGGGCTCAATCCCGATCACCACAAGCGGCAAGGTCCGACGTTCGGCCTGTGTCGAACGTTATCGCAGTGACGGATTCAAACGACTGGACGTGAC

Protein Sequence 

>ML2358c_FadD26_protein
VWYGRNQLFRPRFAERTGGSAG_HYRLHIHRLRVGPEGFC_ELDVVASLYAFMRPC_RTQIVWCAR_SSCNFGATGTGIYYRVLRGSSGRIYRGTSFATAVCDSRRTRFGGVTGFSTDRYSYNFICG__RGEIRM_TRWVERSVCH_DRSA_LERVTPASKSPPAFY_PGLPPIHIRVDTYASRCYGVA_ERYR_RAAKHERLFRRCRKNSEHDRGVMASLVSRHGLDSWGLCSNGRGAKLGVVEPYVIFAAPRLLDATSCHYPGVFFCGTEFCL_AGRTQNVRRRHERTRPRGCGRNHQRQRTSPYRNGETFHRALRSVQSQPLGGTTLVRACGSDRVRGGSGTWHRT_GGSF_LRIPDGQ_G_GPPSRRECRDRTN_LWLP_CIGCANRRSGVHDREPCWNGWGDLGTGRPRCHGVLAEARADCTYVQCKDCQPRAWHFGRSVAADRRSGCYVRRRTVHHGPHQRLAHCRWSQPLPGRHRSDNPGDHRRSGRGDHCAGRPHRAVGGDH_IQGTWSVRGRPHAQSPFGEA_SHIRYIEVT_FACGRPRSGVTGLNPDHHKRQGPTFGLCRTLSQ_RIQTTGRD

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding FadD26 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

22 show weak predicted evidence for PPIs

View all pooled AlphaFold results for FadD26

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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