mmpS4
mL2377
PROBABLE CONSERVED MEMBRANE PROTEIN MMPS4
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2846373 – 2846837
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2377_mmpS4_dna
AACGCCAACGGGGTAAGGGGATTTCAATTTTCAAGCTGTTGTCACGAATTTGGATTCCACTTGTCATCCTTGTGGTGCTCGTGGTTGGGGGATTCGTAGTGTACCGTGTCCACAGTTATTTCGCCTCCGAGAAACGCGAATCCTACGCAGATAGCAACCTGGGAAGCAGCAAGCCGTTCAACCCCAAGCAGATTGTTTACGAGGTCTTCGGCCCACCCGGAACGGTTGCAGATATCAGCTATTTCGATGCTAATTCCGACCCCCAGCGAATCGATGGGGCACAATTGCCATGGTCGTTACTTATGACCACGACCTTGGCCGCAGTGATGGGAAACCTCGTGGCTCAGGGCAATACTGATAGTATCGGCTGCCGGATCATCGTGGACGGCGTAGTCAAAGCTGAGCGAGTTTCCAACGAAGTCAACGCCTACACCTACTGCCTGGTGAAGTCCGCGTGACGGTCAA

Protein Sequence 

>ML2377_MmpS4_protein
NANGVRGFQFSSCCHEFGFHLSSLWCSWLGDS_CTVSTVISPPRNANPTQIATWEAASRSTPSRLFTRSSAHPERLQISAISMLIPTPSESMGHNCHGRYL_PRPWPQ_WETSWLRAILIVSAAGSSWTA_SKLSEFPTKSTPTPTAW_SPRDGQ

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding MmpS4 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

60 show weak predicted evidence for PPIs

View all pooled AlphaFold results for MmpS4

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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