lpd
mL2387
DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2856888 – 2858291
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2387_lpd_dna
ACTATGATGTCGTTGTGCTCGGAGCCGGTCCGGGCGGATATGTCGCTGCCATTCGTGCTGCACAGCTCGGCTTGAGCACAGCAGTCGTCGAACCCAAGTACTGGGGAGGGATCTGCCTCAACGTCGGCTGCATCCCGTCCAAGGTGTTATTGCACAACGCCGAACTCGCACACATCTTCACTAAAGAGGCGAAGACTTTCGGCATCAGCGGCGATGCCAGCTTCGACTACGGGATTGCCTACGACCGTAGCCGCAAGGTGTCCGAGGGTCGCGTCGCCGGCGTGCACTTCCTGATGAAGAAAAACAAGATCACCGAGATACACGGCTACGGCAGATTCACCGACGCCAACACGTTGTCCGTTGAATTGTCGGAAGGCGTCCCTGAAACTCCGCTAAAGGTCACGTTCAACAACGTCATCATCGCCACCGGCAGTAAAACCCGGCTGGTGCCTGGCACGTTGCTGTCGACCAACGTGATTACCTACGAGGAGCAGATCCTGACCCGGGAGCTTCCCGACTCGATCGTCATCGTCGGTGCAGGGGCCATCGGTATAGAATTCGGCTACGTCCTGAAGAACTACGGTGTCGACGTGACGATCGTGGAATTCCTGCCGCGCGCGATGCCCAACGAGGACGCCGAAGTGTCTAAGGAGATCGAGAAGCAATTCAAGAAGATGGGCATCAAAATCCTTACCGGAACCAAAGTGGAGTCCATCTCTGACAACGGTTCGCATGTCTTGGTGGCTGTCAGCAAGGACGGACAATTCCAGGAACTCAAGGCCGACAAAGTGTTGCAGGCCATCGGGTTTGCTCCCAACGTCGACGGTTACGGACTGGACAAGGTCGGGGTAGCTTTGACCGCCGACAAGGCGGTCGACATCGATGACTATATGCAAACCAATGTTTCGCACATCTATGCCATCGGCGATGTTACCGGTAAGCTGCAGCTGGCCCATGTTGCCGAAGCCCAAGGGGTGGTTGCGGCCGAGGCTATCGCCGGCGCAGAGACTTTGGCGCTCAGTGACTACCGTATGATGCCACGCGCAACGTTCTGCCAGCCGAATGTGGCCAGCTTCGGGCTGACCGAGCAGCAAGCCCGAGACGGGGGTTATGACGTCGTAGTCGCTAAGTTCCCGTTTACTGCCAACGCGAAAGCGCACGGCATGGGTGACCCCAGCGGTTTCGTCAAGCTCGTTGCGGACGCCAAGTATGGGGAGCTGTTGGGCGGGCACATGATCGGCCATAACGTGTCCGAGTTACTACCGGAGCTCACGCTCGCGCAGAAATGGGATTTGACGGCCACCGAGCTGGTTCGCAACGTGCATACGCATCCGACGCTGTCAGAGGCGCTGCAGGAGTGCTTTCACGGCCTAATCGGCCATATGATCAACTTCTGAGCATTCA

Protein Sequence 

>ML2387_Lpd_protein
TMMSLCSEPVRADMSLPFVLHSSA_AQQSSNPSTGEGSASTSAASRPRCYCTTPNSHTSSLKRRRLSASAAMPASTTGLPTTVAARCPRVASPACTS__RKTRSPRYTATADSPTPTRCPLNCRKASLKLR_RSRSTTSSSPPAVKPGWCLARCCRPT_LPTRSRS_PGSFPTRSSSSVQGPSV_NSATS_RTTVST_RSWNSCRARCPTRTPKCLRRSRSNSRRWASKSLPEPKWSPSLTTVRMSWWLSARTDNSRNSRPTKCCRPSGLLPTSTVTDWTRSG_L_PPTRRSTSMTICKPMFRTSMPSAMLPVSCSWPMLPKPKGWLRPRLSPAQRLWRSVTTV_CHAQRSASRMWPASG_PSSKPETGVMTS_SLSSRLLPTRKRTAWVTPAVSSSSLRTPSMGSCWAGT_SAITCPSYYRSSRSRRNGI_RPPSWFATCIRIRRCQRRCRSAFTA_SAI_STSEHS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Lpd with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

36 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Lpd

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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