metB
mL2394c
PROBABLE CYSTATHIONINE GAMMA-SYNTHASE METB (CGS) (O-SUCCINYLHOMOSERINE [THIOL]-LYASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2863801 – 2864967
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2394c_metB_dna
ATCGTCGATGAGCGAAGATTACCGGGGACACCACGGCATTACCGGACTAGCCACCAAAGCCATCCATGCTGGCTATCGTCCGGATCCGGCAACAGGGGCAGTGAATGTCCCGATTTATGCCAGTAGTACTTTTGCCCAAGATGGCGTCGGTGAGTTGCGTGGCGGATTCGAATACGCGCGTACCGGCAACCCCATGCGCGCCGCTTTAGAGGCATCCTTGGCCACGGTCGAAGAGGGCGTTTTTGCGCGAGCCTTCAGTTCCGGAATGGCTGCTAGCGACTGTGCCTTGCGGGTCATGCTGCGGCCGGGGGACCACGTGATCATCCCGGATGACGTCTACGGCGGCACCTTCCGGCTGATAGACAAGGTCTTTACTCAATGGAACGTTGACTACACGCCGGTACCGCTGTCTGATTTGGACGCGGTCCGCGCCGCGATCACATCACGGACCCGGCTGATATGGGTGGAAACACCGACCAATCCGCTGCTGTCCATCGCAGATATCACCAGCATCGGCGAACTAGGCAAAAAGCACTCAGTAAAGGTGTTGGTGGACAACACCTTTGCTTCACCCGCGCTGCAACAGCCGCTGATGCTGGGGGCAGACGTCGTGTTGCACTCGACCACAAAGTACATCGGCGGCCACTCTGATGTGGTGGGCGGCGCGCTAGTCACCAACGACGAAGAGCTGGACCAGGCTTTCGGCTTCTTGCAGAACGGAGCCGGTGCGGTGCCGAGCCCGTTCGACGCGTACCTAACGATGCGCGGATTGAAGACTTTAGTGCTGCGGATGCAGCGGCACAACGAAAATGCCATTACTGTAGCGGAATTCCTGGCTGGGCATCCGTCGGTGAGCGCCGTGCTGTATCCGGGCTTGCCCAGCCATCCCGGGCATGAGGTCGCTGCACGGCAGATGCGCGGCTTCGGCGGCATGGTTTCGTTGCGGATGCGAGCCGGCCGACTAGCCGCCCAGGATCTGTGTGCCCGCACCAAGGTGTTTACCTTGGCTGAATCCTTGGGTGGAGTGGAGTCGCTGATTGAGCAGCCCAGTGCCATGACGCACGCGTCGACAACCGGGTCGCAATTGGAAGTACCCGACGACCTGGTGCGGCTTTCGGTCGGTATTGAAGACGTCGGCGACCTGCTGTGCGACCTCAAGCAGGCGTT

Protein Sequence 

>ML2394c_MetB_protein
IVDERRLPGTPRHYRTSHQSHPCWLSSGSGNRGSECPDLCQ_YFCPRWRR_VAWRIRIRAYRQPHARRFRGILGHGRRGRFCASLQFRNGC_RLCLAGHAAAGGPRDHPG_RLRRHLPADRQGLYSMER_LHAGTAV_FGRGPRRDHITDPADMGGNTDQSAAVHRRYHQHRRTRQKALSKGVGGQHLCFTRAATAADAGGRRRVALDHKVHRRPL_CGGRRASHQRRRAGPGFRLLAERSRCGAEPVRRVPNDARIEDFSAADAAAQRKCHYCSGIPGWASVGERRAVSGLAQPSRA_GRCTADARLRRHGFVADASRPTSRPGSVCPHQGVYLG_ILGWSGVAD_AAQCHDARVDNRVAIGSTRRPGAAFGRY_RRRRPAVRPQAGV

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding MetB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

3 show weak predicted evidence for PPIs

View all pooled AlphaFold results for MetB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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