hemA
mL2422c
PROBABLE GLUTAMYL-TRNA REDUCTASE HEMA (GLUTR)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2897502 – 2898905
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2422c_hemA_dna
ATGCTGCCGTGAGCATCTTGCTCTTCGGGGTTTCGCACCGCAGTGCGCCGGTCTCTGTCTTAGAACAACTCAGCCTGGACAGATCCGATCAGATCAAGATCGTCGACCGGGTGCTGCAGTCCCCGCTGGTGACCGAGGCGATGGTGCTGTCGACCTGTAACCGTGTCGAGGTTTACGCCGTGGTGGAAGCGTTCCACGCGGGATTATCAGTGATTGGGCAAGTGCTGTCGGAATACTCCGCGATGTCGATCGGGGACCTGACCAAATACGCTTATGTACGCTACAGCGAGGCTGCTGTCGAGCACTTGTTCACGGTTGCCAGCGGTCTGGATTCAGCGGTGGTCGGCGAGCAGCAGGTGCTGGGTCAGGTGCGTCGCGCGTATGCCGCCGCTGAGGCTAATCGCACGGTAGGCCAGGTGTTGCATGAGGTGGCCCAACGAGCGTTGTCGGTGGGTAAGCGGGTGCATTCCGAAACTGCCATTGACGCTGCCGGGGTCTCGGTGGTGTCGGTCGCCCTTGGCATAGCTGGACGCACATTGGGCGGGCTGGCGGGCCGGATCGCGGTGGTGATTGGCGCTGGCGCGATGGGTGCACTCTCGTCGTCGTACCTGACGCAGGCCAACGTCGGACGTATACATGTACTCAACCGGTCGTTGTCTCGAGCGCGGCGGCTGGCCGGCAAGATCGGTGAATCGGGCGTGCCGGCCGACGTGTGGACTCTTAATCACCTTGACGAAGCATTGGCGGACGCTGACCTAGTGGTCAGCTGTACGGGGGCGGTAAGCCCCGTGGTTTCGCTGGCTGACGTGCATCATGCATTGGCCGCTATGCGCCGTGACGAAACGACTCGGCCGCTGGTGATATGCGATTTGGGCATGCCGCGTGACGTGGATCCGGCTGTGGCCAAACTGCCCGGCGTTTGGGTCGTCGATGTGGAAGGCGTGCAGCGTGAACCGTCGGCCCGTGCCAGTGCCGCCGACGTCGATGCCGCGCGCCGCATTGTGGCGGCTGAAGTGGCCACATATCTGACTAGGCAGCGGATGGCCGAGGTGGCCCCGACGGTGACAGCGTTGCGTCAGCGAGCTGCCGATGTGGTCGAAGCGGAGTTACTGCGCCTAGACCACCGGCTGCCAGGGCTGGAAAGCGCTCAGCGCGAGGAGGTGGCACGCACCGTGCGACGGGTGGTGGACAAGCTGCTACACGCGCCTACCGTGCGGATCAAGCAGCTTGCCAGTGCTCCCGGCGGTGACAGCTACACCGAGGCGCTGCGTGAGCTTTTCGAGCTTGATCAGACCGCTGTCGACGCGGTCGCCACCGCGGGTGAATTACCAGTGATGGTAAGTGGGTTCAGCGATACCACTAGGTACGGCACAAGCCCTGCCCAGAGCAGCTCAAAATATCACG

Protein Sequence 

>ML2422c_HemA_protein
MLP_ASCSSGFRTAVRRSLS_NNSAWTDPIRSRSSTGCCSPRW_PRRWCCRPVTVSRFTPWWKRSTRDYQ_LGKCCRNTPRCRSGT_PNTLMYATARLLSSTCSRLPAVWIQRWSASSRCWVRCVARMPPLRLIAR_ARCCMRWPNERCRWVSGCIPKLPLTLPGSRWCRSPLA_LDAHWAGWRAGSRW_LALARWVHSRRRT_RRPTSDVYMYSTGRCLERGGWPARSVNRACRPTCGLLITLTKHWRTLT_WSAVRGR_APWFRWLTCIMHWPLCAVTKRLGRW_YAIWACRVTWIRLWPNCPAFGSSMWKACSVNRRPVPVPPTSMPRAALWRLKWPHI_LGSGWPRWPRR_QRCVSELPMWSKRSYCA_TTGCQGWKALSARRWHAPCDGWWTSCYTRLPCGSSSLPVLPAVTATPRRCVSFSSLIRPLSTRSPPRVNYQ_W_VGSAIPLGTAQALPRAAQNIT

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding HemA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

41 show weak predicted evidence for PPIs

View all pooled AlphaFold results for HemA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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