ML2425
mL2425
conserved hypothetical protein
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2901013 – 2901513
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2425_ML2425_dna
TCCCTTAGAGGCCGAAGGACTAATCGGCAAGCATTACCGGCAGTTGGATCACTTCCAAGTTGGACGCGAGAAAATCCGTGAGTTCGCGATCGCGGTTAAAGACGACCACCCAACCCACTACAACGAAACTGCAGCCTTCGAGGCCGGATACCCTGCACTAGTGGCTCCGCTAACCTTCCTGGCGATCGCTGGGCGACGCGTGCAGCTCGAGATTTTTACTAAATTCAACATCCCGATCAATGTCGCCCGGGTTTTCCATCGCGACCAAAAATTTCGCTTCTACCGCACGATCCTGGCACAGGATAAGCTCTACTTCGACACCTACCTCGACTCGGTGATCGAGTCACATGGCACTGTGATCGCAGAAGTCCGCAGCGAGGTCACCGATACGGAGGGCAAGGCGGTCGTCACCAGTATTGTCACTATGCTGGGCGAATTGGCCCGTCAGGATGCTACCGCTGAAGAAACCGTCGCTGCAATCGCTTCTATATGAAAGGCGAA

Protein Sequence 

>ML2425_ML2425_protein
SLRGRRTNRQALPAVGSLPSWTRENP_VRDRG_RRPPNPLQRNCSLRGRIPCTSGSANLPGDRWATRAARDFY_IQHPDQCRPGFPSRPKISLLPHDPGTG_ALLRHLPRLGDRVTWHCDRRSPQRGHRYGGQGGRHQYCHYAGRIGPSGCYR_RNRRCNRFYMKGE

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML2425 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

3 proteins show strong predicted evidence for PPIs

6 show intermediate predicted evidence for PPIs

43 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML2425

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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