cmaA2
mL2426
CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE 2 CMAA2 (CYCLOPROPANE FATTY ACID SYNTHASE) (CFA SYNTHASE) (CYCLOPROPANE MYCOLIC ACID SYNTHASE 2) (MYCOLIC ACID TRANS-CYCLOPROPANE SYNTHETASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2901524 – 2902450
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2426_cmaA2_dna
GTCACAGAGCCATCCGGCCAAAACCCCTCGTAAACAGCTGAAACCACCGATCGAAGCCGTACAGTCGCATTACGACCGATCGAATGAGTTCTTCAAGCTGTGGCTCGATCCATCGATGACCTACAGCTGCGCATACTTTGAACGCCCCGACCTGACGCTGGAAGAGGCCCAGCGCGCTAAGCGTGACCTCGCCTTGAGCAAGCTTGGGCTAGAACCCGGTATGACTCTGCTCGACATCGGCTGCGGCTGGGGATCGACCATGCTGCACGCGATCGAAAAGTACGACGTTAATGTGATTGGCTTGACGCTGAGCGCGAATCAGCTCGCCCACAACAAGCTGAAGTTTGCCGAAATAGACCACACCCGAACAGACCGGACCAAGGACGTACGGCTGCAAGGCTGGGAACAATTCGACGAACCGGTCGACCGCATCATCTCACTCGGCGCGTTCGAGCATTTTGCTGATGGCGCAGGCGACGCCGGATTCGAACGCTACGACAGCTTCTTCAAGATGTGCTACGACGTGCTGCCCGACGATGGCAGGATGCTGCTGCACACAATCATCGTGCCTGATGCCAAGGAAACCAAGGAGCTGGGCTTGACGACGCCGATGAGCCTGCTCCGCTTCATCAAGTTCATCTTGACCGAGATCTTCCCTGGCGGTCGGCTGCCGAAGATCTCGCAGGTCGACCACTATTCATCCAACGCTGGTTTCACGGTCGAGCGGTACCATCGGATCGGGTCCCACTATGTCCCGACGCTGAACGCCTGGGCCGCAGCGCTGGAAGCTCACAAGGACGAGGCCATCGCACTGCAGGGGCGGCAAATCTACGACACCTACATGCACTACCTGACGGGGTGTTCAGACCTATTCCGCGACCGTTACACCGACGTCTGCCAGTTCACCTTGGTCAAGTAGCTACGCGA

Protein Sequence 

>ML2426_CmaA2_protein
VTEPSGQNPS_TAETTDRSRTVALRPIE_VLQAVARSIDDLQLRIL_TPRPDAGRGPAR_A_PRLEQAWARTRYDSARHRLRLGIDHAARDRKVRR_CDWLDAERESARPQQAEVCRNRPHPNRPDQGRTAARLGTIRRTGRPHHLTRRVRAFC_WRRRRRIRTLRQLLQDVLRRAARRWQDAAAHNHRA_CQGNQGAGLDDADEPAPLHQVHLDRDLPWRSAAEDLAGRPLFIQRWFHGRAVPSDRVPLCPDAERLGRSAGSSQGRGHRTAGAANLRHLHALPDGVFRPIPRPLHRRLPVHLGQVATR

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding CmaA2 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

20 show weak predicted evidence for PPIs

View all pooled AlphaFold results for CmaA2

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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