senX3
mL2440c
PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2915136 – 2916461
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2440c_senX3_dna
ATGTGACTGTGTTCTCGGCTCTGTTGTTGGCCGGGGTATTGTCCGGGTTGGCGTTTGTTGTTGGTATTGTGGCAGGAATCCGGCTGTCGCCGCGACTAATCGAACGCCGGCAAAGACTGGCTAACGAATGGGCGGGCATCACTGTTTTGCAGATGCTGCAACGCATCATCGCGTTGATGCCGCTAGGTGCTGCGGTGGTTGATACCTATCGTGATGTAGTTTACCTCAACGAACAGGCCAAGGAGCTAGGACTCGTGCGCGACCGGCAGCTCGATGACCAGGCCTGGCGGGCAGCACAGCAGGCGCTGGGCGGTGACGATGTCGAATTTGACCTGTTGCCCGGAAAACGCCCGGCTGCGGGCCGGTCTGGGTTATCGGTGCACGGCCACGCTCGACTGCTAAGTGAGAAAGACCGCCGGTTCGCCGTGGTCTTCGTCCACGACCAGTCCGACTATGTGCGCATGGAGGCGGCTAGGCGTGACTTCGTAGCCAATGTTAGCCACGAGCTCAAGACCCCGGTCGGCGCCATGGCCTTGCTAGCTGAGGCTCTGCTGGCATCGGCGGATGACGCCGAAACCGTGAGCCGGTTCGCCGAGAAGGTGCTCATCGAGGCCAATCGATTAGGATACATGGTTGCTGAGCTCATAGAGTTGTCCCGGCTGCAGGGCGCCGAGCGGCTGCCTAACGTAACGGACATTGACGTCGATATCATCGTGTCCGAGGCGATTGCGCGCCATAAGGTGGCCGCCGACACCGCTGCTATCGAGGTTCGCACCGATCCGCCTAGCGGTTTGCGGGTATTGGGCGACCAAACTCTACTGGTTACCGCGCTAGCCAATCTGGTGTCCAACGCGATTGCCTACTCGCCGGGTGGTTCGCTGGTGTCGATCAGCCGTCGCCGTCGTGGCGACAATATCGAGATCGCCGTCACCGACCGCGGCATTGGCATCGCTCTTGAAGATCAGGAGCGGGTCTTCGAACGCTTCTTCCGCGGAGACAAGGCGCGCTCGCGGGCTACCGGTGGCAGCGGGCTGGGGCTGGCCATCGTCAAACACGTTGCCGCCAACCACAATGGCAGTATCGGTGTGTGGAGCAAGCCGGGAACCGGATCTACGTTCACCCTGTCTATTCCGGCGGCCATGCCGCTTTACCAGGACAACGATGAGCAATCCGGGCAACCCCGGGGCTGCGATATGTGGCTCAATAGGCCGCAACGAGAGGAAGAAGAGTTTAAGTCGATGACACCCGCGCAGGCGATGATGCAGAGCGAAGTGACGAGAGGGAATGTGAATGATAAGTGTCCTGATTGTGGAGGACGAGGAATCG

Protein Sequence 

>ML2440c_SenX3_protein
M_LCSRLCCWPGYCPGWRLLLVLWQESGCRRD_SNAGKDWLTNGRASLFCRCCNASSR_CR_VLRWLIPIVM_FTSTNRPRS_DSCATGSSMTRPGGQHSRRWAVTMSNLTCCPENARLRAGLGYRCTATLDC_VRKTAGSPWSSSTTSPTMCAWRRLGVTS_PMLATSSRPRSAPWPC_LRLCWHRRMTPKP_AGSPRRCSSRPID_DTWLLSS_SCPGCRAPSGCLT_RTLTSISSCPRRLRAIRWPPTPLLSRFAPIRLAVCGYWATKLYWLPR_PIWCPTRLPTRRVVRWCRSAVAVVATISRSPSPTAALASLLKIRSGSSNASSAETRRARGLPVAAGWGWPSSNTLPPTTMAVSVCGASREPDLRSPCLFRRPCRFTRTTMSNPGNPGAAICGSIGRNERKKSLSR_HPRRR_CRAK_REGM_MISVLIVEDEES

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding SenX3 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

49 show weak predicted evidence for PPIs

View all pooled AlphaFold results for SenX3

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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