murB
mL2447c
PROBABLE UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINE REDUCTASE MURB (UDP-N-ACETYLMURAMATE DEHYDROGENASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2922797 – 2923900
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2447c_murB_dna
TACCTGCCATGAAACGGAGCGCTGTCGGTTCGTTCTTTGCCGGCGCGCATGTCGCAGAGGCGGTGTCACTTGCGCCGTTGACCACGTTGCGGGTCGGTCCGGTCGCCCAGCGGGTTATAACGTGCGCCAGCACTGAACAGGTAGTCGACGTTATACGGCAGCTAGACGCACCAGCCGGCGGCAGGGGAGCTGGGCCGCTGCTGATATTTGCTGGCGGCTCCAACCTGGTGATTGCCGACACGCTGGCCGACTTGACTGCGGTGCGCTTGGCCAATGCCGGCATCACTATCGACGGCAACCTAGTGCGTGCCGAGGCTGGCGCGGTCTGGGACGACGTGGTGGTTAGGGCCATCGAGCACGGGCTCGGTGGGCTGGAATGCCTGTCTGGTATCCCCGGATCGGCTGGGGCCACTCCGGTGCAAAATGTGGGTGCCTACGGCGCAGAAGTGTCTGACACAATCACTCGGGTCCGGCTGCTGGAGCGCAGTAGCGGCTCGGTTCGTTGGGTCTCCGCCTGCGAGTTGCGTTTTGGTTATCGTACCAGCGTTTTCAAGCAAGCCGACCCGTCAGGGTCGCAACCGCCTGCTGTGGTGCTGGAAGTCGAGTTCAAGCTCGATGCATCGGGGCAGAGCGCACCGTTGCACTATGGTGAGCTGGTGGCCACACTCGACGCGACTAGTGGGCAGCGCGCCAACCCACACGCGGTGCGCGAGGCGGTGCTGGCGCTGCGTGTTCGCAAGGGTATGGTGCTCGATGCGGCAGACCATGACACCTGGAGTGTCGGATCTTTCTTTACTAATCCGGTAGTAGCGCCGGACGTTTACCGTCAGCTAGCCAAGATGGTGGACGGGCCGGTGCCGCATTATCCGGCGCAGGACGGCGTCAAGCTGGCCGCTGGCTGGCTGGTGGAACGGGCCGGCTTCGGTAAGGGTTATCCTGATGGTGCAGCTCCATGCCGGCTTTCCACCAAACATGTGCTTGCCTTAACCAACCGCGGTGCCGCCACCGCCGAAGATGTGGTAACTCTGGCCCGCACCGTTCGTAATGGGGTCCTAGAGGTGTTTGGTATCACACTCGAACCTGAGCCTGCACTGGTTGGGTGCG

Protein Sequence 

>ML2447c_MurB_protein
YLP_NGALSVRSLPARMSQRRCHLRR_PRCGSVRSPSGL_RAPALNR_STLYGS_THQPAAGELGRC_YLLAAPTW_LPTRWPT_LRCAWPMPASLSTAT_CVPRLARSGTTWWLGPSSTGSVGWNACLVSPDRLGPLRCKMWVPTAQKCLTQSLGSGCWSAVAARFVGSPPASCVLVIVPAFSSKPTRQGRNRLLWCWKSSSSSMHRGRAHRCTMVSWWPHSTRLVGSAPTHTRCARRCWRCVFARVWCSMRQTMTPGVSDLSLLIR__RRTFTVS_PRWWTGRCRIIRRRTASSWPLAGWWNGPASVRVILMVQLHAGFPPNMCLP_PTAVPPPPKMW_LWPAPFVMGS_RCLVSHSNLSLHWLGA

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding MurB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

16 show weak predicted evidence for PPIs

View all pooled AlphaFold results for MurB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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