pcaA
mL2459
MYCOLIC ACID SYNTHASE PCAA (CYCLOPROPANE SYNTHASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2932070 – 2932957
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2459_pcaA_dna
GCAGCTGACGCCGCATTTTAGAAACGTACAAGCCCATTACGACCTATCTGACGACTTCTTCCGCCTGTTCCTCGACCCCACCCTGACCTACAGCTGCGCGTATTTCGAGCGTGACGACATGACGCTCGAGGAAGCGCAGCTCGCCAAGGTCGATCTAGCGTTGGGAAAGCTCAAGCTTGAGCCCGGGATGACGTTGCTGGACATCGGCTGTGGTTGGGGCGCCACCATGAAACGCGCGATTGAAATATACGACGTCAACGTTATAGGCCTGACCCTGTCCGAGAATCAGGCCGCCCACGTTCAGAAGACATTCGACGAGTTAGACACCCCCCGAACCCGGCGGGTACTGCTGGAGGGCTGGGAGAAGTTCCACGAACCTGTCGACCGGATTGTCTCGATCGGTGCATTCGAGCACTTCGGCCGCCAACGCTATGCACGCTTCTTCAAGATGGCCCACGAAGTCCTACCGGCCGACAGCGTGATGTTACTGCACACCATCGTCCGTCCCACCTTTAAAGATGCCAGAGCGCGGGGCATGACTTTAACCCACGAGATTGTTCACTTTACCCAATTCATTTTGGCTGAGATCTTCCCTGGTGGCTGGTTACCAACAGTACCGACGGTGGAAGAGCACGCCACCGCGGCCGGTTTCAAGTTCACACGGATCCAGTCGCTGCAGCTACACTACGCCAAAACCCTGGACTTGTGGGCCGCCAGACTGGAAGCCAACAAGAACAAGGCGATCGCCATCCAGTCTGAAGAGGTCTACGACCGCTACATGAAGTACCTAACTGGGTGCGCAAAGCTGTTCCGCGACGGGTACACTGATGTCGACCAGTTCACTTTGGAAAAGCAACCAGCCACCGCACGCCGGCATTGAGTCGCCCG

Protein Sequence 

>ML2459_PcaA_protein
AADAAF_KRTSPLRPI_RLLPPVPRPHPDLQLRVFRA_RHDARGSAARQGRSSVGKAQA_ARDDVAGHRLWLGRHHETRD_NIRRQRYRPDPVRESGRPRSEDIRRVRHPPNPAGTAGGLGEVPRTCRPDCLDRCIRALRPPTLCTLLQDGPRSPTGRQRDVTAHHRPSHL_RCQSAGHDFNPRDCSLYPIHFG_DLPWWLVTNSTDGGRARHRGRFQVHTDPVAAATLRQNPGLVGRQTGSQQEQGDRHPV_RGLRPLHEVPNWVRKAVPRRVH_CRPVHFGKATSHRTPALSRP

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PcaA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

3 show intermediate predicted evidence for PPIs

26 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PcaA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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