tyrA
mL2472c
PREPHENATE DEHYDROGENASE TYRA (PDH) (HYDROXYPHENYLPYRUVATE SYNTHASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2947166 – 2948149
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2472c_tyrA_dna
CGCAAACTGTGTCAATCTTGGATGGTGGCTGGGACTGCGTCGGGCGACCGGTGTGCGTGCTTGGGCTGGGATTGATCGGCGGATCGATCATGCGGGCCACGGCGGAGGCCGGTCGTGAGGTTTTCGGCTATAATCGTTCAGTGAAAGGCGCGCAGAGCGCTCGGTCAGACGGTTTTGACGCCACTACCAAACTTGCTGACGCGTTAGTTCGCGCCGCCGATACCCACGCATTGATCGTGCTGGCTGTGCCGATGCCGGCATTGCCGGCCATGCTCGCCCACATTCGCGAATTGGCGCCCAACTGTCCGCTCACTGATGTTACCAGCGTCAAAACCGCGGTGCTCGACGCGGTTGTTTCGGTTGGTTTGCAGGCCCGCTTCGTCGGTGGTCACCCGATGACCGGCACTGCGCAATCGGGTTGGGGCGCCGGACATGGCGGGTTGTTCAACAGGACTTCCTGGGTGCTTAGTGTAGACGACCATGTGGACCCCGCGGTGTGGTCAATGGTTATGACATTGGCGTTGGATTGCGGCGCGCTGGTATTACCGGCAAAATCCGACGAGCACGACGCCGCTGCAGCTGCCATTTCGCATATGCCGCACTTGCTCGCTGAAGCTTTGGCTGTAGCCGCCGCTGAGGTTCCGCTGGCGTTCGCGGTGGCGGCAGGATCGTTCCGTGACGCCACCCGAGTAGCCGGAACCGCTCCGGACTTAGTGCGTGCGATGTGCGAAGGAAACTCCGGCCAACTGCTGTCGTCCGTCGACCGGGTCATCGAGTTGCTTTGCCGTGCCCGCGACTCCCTGGCTTGCAACAATTCAGTGGCTGAACTCGTCGAAGCGGGCCATGCCGCGCGCGCGCGTTACGACAGCTTCCCGCGCTCCGACATCGTCACCGTCATCATCGGCGCGGAGAATTGGCGCGAAGACCTGGCGGCTGCAGGCCGAGCAGGTGGGGTGATCAGATCCGCTCTGCCAAGCCTGGGTA

Protein Sequence 

>ML2472c_TyrA_protein
RKLCQSWMVAGTASGDRCACLGWD_SADRSCGPRRRPVVRFSAIIVQ_KARRALGQTVLTPLPNLLTR_FAPPIPTH_SCWLCRCRHCRPCSPTFANWRPTVRSLMLPASKPRCSTRLFRLVCRPASSVVTR_PALRNRVGAPDMAGCSTGLPGCLV_TTMWTPRCGQWL_HWRWIAARWYYRQNPTSTTPLQLPFRICRTCSLKLWL_PPLRFRWRSRWRQDRSVTPPE_PEPLRT_CVRCAKETPANCCRPSTGSSSCFAVPATPWLATIQWLNSSKRAMPRARVTTASRAPTSSPSSSARRIGAKTWRLQAEQVG_SDPLCQAWV

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding TyrA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

12 show weak predicted evidence for PPIs

View all pooled AlphaFold results for TyrA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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