ML2474
mL2474
possible cytidine/deoxycytidylate deaminase
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2948774 – 2949289
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2474_ML2474_dna
CGCAGCGGGGCGCCGCCATCAGACCCGATCGGTTACCACTGACGAAGATTTGATCCGTGCCGCACTAACAGTTGCCACGACGGCGGGGTCGCGCGATGTACCGATTGGGGCAGTGGTCCTCGGCGCCGACGGAAACGAACTCGCCCGGGCAGTAAATGCCCGTGAAGCCATTGGCGATCCCACCGCGCACGCCGAAATTTTGGCAATGCGGGCGGCGGCCGGTACACTAGGCAATGGATGGCGGCTGGAGGGGACTACGTTGGCAGTCACCGTTGAACCGTGCACCATGTGCGCGGGTGCTCTGGTCCTGGCACGTATCGAGCGACTGGTGTTTGGAGCCTGGCAACCCAAGACCGGAGCGGTCGGGTCGCTGTGGGATGTGGTCCGCGACCATAGACTCAACCATCGCCCAGCCGTACGCGGCGGAGTGCTTGCTCAGGAGTGCACAGCACCACTGGAGGCGTTCTTTGCTCACCAGCGATTGAGTAAAGGGCCGCCGGTTCGGTAAACTACCCA

Protein Sequence 

>ML2474_ML2474_protein
RSGAPPSDPIGYH_RRFDPCRTNSCHDGGVARCTDWGSGPRRRRKRTRPGSKCP_SHWRSHRARRNFGNAGGGRYTRQWMAAGGDYVGSHR_TVHHVRGCSGPGTYRATGVWSLATQDRSGRVAVGCGPRP_TQPSPSRTRRSACSGVHSTTGGVLCSPAIE_RAAGSVNYP

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML2474 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

34 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML2474

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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