ML2491
mL2491
CONSERVED HYPOTHETICAL PROTEIN
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2966123 – 2967706
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2491_ML2491_dna
CTATCGGTACATCACTGATCGCAGAAACCTCACGGGCCACTATCGTCACATAACTAATCACGGACGTCGACGTGACGTCCTGCCCCCGGGAAGGTATGGCATGTCGGCGTTTCGTCTAATCATTACGGTAGTCGCCGCGTCAGCAGTCGCTGCCGGACTCATAGTCGCAGTGGGCTTCGCGCCACCAGCTAGCACTATGCCTTGTAGCATGCCCGAAGCCAACGTCTTGCCGCCTGCGGTACCCCCAACGATGCCCGCACCAGCGCCGATCGTCCAACTACCAACTGGGCGCCGGCCTTCCAACGCGAATGACCATGCTCCGATGCCCAAGCTGGGGCCGCTGATCGCTTCTTTGTTCAAACCTCCTGCGCCTAATAATCACTATTCCACGCCACTACAACTTCAAGCGGAGCTAGTACCGCCCGGACCCAACCCCGCTGTCCCCGGACAGCCCCCGAACACGGTACGGCGTGTTCCGAATGCACTCCCAGTCCCGCCGACGGCACCCCGGCTGGAGCCGGGTCCACCGCCCACTGCCTCCATTGCGGGCGCACCGACCTCGCTCGTCGAGTGGGTGACCGGACCCAACAGCCCAAACAAAACACTCCAACGTTTCGGCATCTCTGGAACCGACCTCGGGATCCCTTGGGACAACGGCGATCCCACCAACCATCAGGTCCTTATGGCCTTCGGTGACAGTTTTGGCTACTGTAGCGTAAAAGGCCAGCAACGACGATACAACATCTTGTTCCGCAGTTCAAACCAAGATCTGTCGCACGGAATCCGGATTGCGGACGGCGTGCCTAACGACAAGTACTCCGGTTCACCGGTGTGGACAACTGGCCTCGCTAAGCAGGTCGTCAACACCATCCATCGAGCACCGCACGAGACGGGAATCATTCCGACAACCGCCATCTCCATCGGAAAAACTCAATACATGAACTACATGTCCATAAAGAAATGGGGCCGTGACGGCGAATGGACGACAAACTACTCGGCAATCGCTAGGTCAATCGACAACGGCCAAAGTTGGGGGACCTACCCCGGCACTATCCGCACCGCCTCGCCGGACGCCATACCTGGGACTCATTTTGTTCCAGGTAACCAGAATTTCCAAATGGGGGCGTTCATGCGGGGTAACGATGGCTACCTCTACTCGTTCGGGACCCCGTCCGGGCGCAGTGGTGCGGCGTATCTAGCTCGAGTGCCCCAAAACTTGGTGCCAGACCTCAGTAAATACCAATACTGGAACGGAAACTGGGTTCCCAACAATCCAGGGGCCGCTACGCCATTGTTCTCGGGTCCTGTGGGTGAAATGTCAGCACAGTACAACGACTATCTTAAGCAATATATCATTCTCTACAGCAACGGTGACAGCAACGACGTTGTGGCGCGAACAGCACCTGCTCCACAAGGACCGTGGAGTCCAGAGCAGCCTCTGGTGTCATCGTTTCAGATGCCTGGTGGTATCTACGCGCCGATGATCCATCCCTGGTCGTCAGGTCGAGACTTGTACTTCAATCTGTCACTGTGGTCGGCGTACGACGTCGTGTTGATGCACACCGTGTTGCCCTAATCTTTGCG

Protein Sequence 

>ML2491_ML2491_protein
LSVHH_SQKPHGPLSSHN_SRTST_RPAPGKVWHVGVSSNHYGSRRVSSRCRTHSRSGLRATS_HYAL_HARSQRLAACGTPNDARTSADRPTTNWAPAFQRE_PCSDAQAGAADRFFVQTSCA__SLFHATTTSSGASTARTQPRCPRTAPEHGTACSECTPSPADGTPAGAGSTAHCLHCGRTDLARRVGDRTQQPKQNTPTFRHLWNRPRDPLGQRRSHQPSGPYGLR_QFWLL_RKRPATTIQHLVPQFKPRSVARNPDCGRRA_RQVLRFTGVDNWPR_AGRQHHPSSTARDGNHSDNRHLHRKNSIHELHVHKEMGP_RRMDDKLLGNR_VNRQRPKLGDLPRHYPHRLAGRHTWDSFCSR_PEFPNGGVHAG_RWLPLLVRDPVRAQWCGVSSSSAPKLGARPQ_IPILERKLGSQQSRGRYAIVLGSCG_NVSTVQRLS_AIYHSLQQR_QQRRCGANSTCSTRTVESRAASGVIVSDAWWYLRADDPSLVVRSRLVLQSVTVVGVRRRVDAHRVALIFA

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML2491 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

25 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML2491

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.