hspR
mL2493c
PROBABLE HEAT SHOCK PROTEIN TRANSCRIPTIONAL REPRESSOR HSPR (MERR FAMILY)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2969306 – 2969704
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2493c_hspR_dna
GGTAATCGGTGATGACTAGAAACTCTAGAGACCCCAGGCAACAAGAATCCCGGACGTTTTTGATCTCGGCGGCTGCTGAGCTAGCCGGTATGCACGCGCAGACCTTGCGTACCTATGATCGACTCGGGCTGGTCAGCCCGAGTCGGGCTTCTGGTGGTGGGCGCCGTTATTCGCAGCATGACGTCGAGCTGCTGCGCCAGGTACAGCGACTCTCGCAAAATGAAGGGGTTAACCTCGCTGGCATTAAGCGCATCATCGAGCTGACCAATCAGGTTGAAGCGTTGCAGTTGAAGCTGCAGGAATTGACTGATGAGTTGGTGATGTTGCGCGCCAACCAGCGTCGCGATCTTGCGGTGGTGCCCAAGAGCACGGCGCTGGTCCTCTGGCAGCCGCGAAAGC

Protein Sequence 

>ML2493c_HspR_protein
GNR__LETLETPGNKNPGRF_SRRLLS_PVCTRRPCVPMIDSGWSARVGLLVVGAVIRSMTSSCCARYSDSRKMKGLTSLALSASSS_PIRLKRCS_SCRN_LMSW_CCAPTSVAILRWCPRARRWSSGSRES

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding HspR with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

32 show weak predicted evidence for PPIs

View all pooled AlphaFold results for HspR

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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