grpE
mL2495c
PROBABLE GRPE PROTEIN (HSP-70 COFACTOR)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2970888 – 2971577
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2495c_grpE_dna
GAGTCCAAGTGACCGAAGGCAATCCACACGAACAGGTGACGGTCACCGACAAACGACGGATCGATCCCGATACTGGCGAAGTACGATCTATACCTCTCGGCGACACGCCGGGAGGTAGCGAGCCGGCTGGTATGACCGACCGAAGTGCCAACAGTACCGACACAATGGTCGACAAAGTTGCTGAGCTGACTAGCGATCTGCAGCGGGTGCAGGCCGATTTTGCCAACTACCGTAAGCGAGCGTTGCGCGACCAGCAGACGGCTTCGGATCGAGCCAAGGCCACTGTCATCAGCCAATTGTTGGGTGTGCTTGACGATTTCGATCGTGCCCGCGAGCACGGCGATCTGGACTCGGGTCCGCTGAAGTCGGTCGCCGACAAGCTAATGAGCGCATTGACCGGGCTCGGGCTGGTGGCGTTTGGCGTCGAGGGAGAAGACTTCGACCCGGTGCTGCACGAAGCCGTGCAGCATGAGGGCGATGGTGGGGAAGGCTCCAAGCCGGTGATCGGTGACGTCCTCCGGCACGGCTACAAATTGGGCGATCAAGTGCTGCGGCACGCCTTGGTCGGGGTGGTTGACACGATCGCAGGCGATGGTGCCGAAACGGTTGCCATAGTCGCACCTGTCGACAGCACAGCCAAAACCGAGCAAGGTGAACTGGGCGATAACGTGACACCGCACAAGGAGGACG

Protein Sequence 

>ML2495c_GrpE_protein
ESK_PKAIHTNR_RSPTNDGSIPILAKYDLYLSATRREVASRLV_PTEVPTVPTQWSTKLLS_LAICSGCRPILPTTVSERCATSRRLRIEPRPLSSANCWVCLTISIVPASTAIWTRVR_SRSPTS__AH_PGSGWWRLASREKTSTRCCTKPCSMRAMVGKAPSR_SVTSSGTATNWAIKCCGTPWSGWLTRSQAMVPKRLP_SHLSTAQPKPSKVNWAIT_HRTRRT

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding GrpE with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

17 show weak predicted evidence for PPIs

View all pooled AlphaFold results for GrpE

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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