ML2501
mL2501
PROBABLE IRON-SULFUR-BINDING REDUCTASE
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2980189 – 2982831
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2501_ML2501_dna
GCAGATGCTGATCAGAATGGTGCTAGGCCTGAGTATGACCGCGGTCGTGCTGCTGTTCGCGGCACGTCGCGTCTTGTGGCTATACAAGCTGACCATGTCCGGTCAACCGGCCAACGGACGCACCGACGAGCTAGGCACCCGAATCTGGACGCAAATCACCGAGGTCTTCGGGCAACGGCGACTGTTGCAGTGGTCACTGCCAGGTTTGACGCACTTATTCACCATGTGGGGCTTCTTCATCTTACTTACGGTCTACATCGAGGCCTACGGCGTGCTATTCCAGCCGAACTTCCACCTCCCGATCATCGGCCGCTGGAACGCGATAGGCTTCCTTCAGGACTTTTTTGCGCTAGCTGTACTGACTAGCACCGTCACGTTCGCGATTATCCGCATGCGTAACGAGCCAAAAGAATACGGCCGCAAGTCCCGCTTCTACGGATCCCATACCGGCGGTGCGTGGTTGATCCTGTTCATGATCTTCAACGTGATTTGGACGTATGCCGTTTTTCGTGGGGCATCGGTCGATGCACTCGGCGAGGCGTTCCCTTACAACAGCGGCGCATTCTTCTCGCACGCCATAGCCGCAGTGCTGTATCCGTTGGGTCAAGGTGCTAACCAGATCATCGAAACCGTTGCGCTGTTGCTGCACATAGGCGTCATGCTGGCCTTCCTGCTGATCGTGCTGCACTCCAAACACCTGCACATTTTCCTAGCGCCGATCAACGTCACGTTTAAACGGCTGCCCGACGGGCTGGGCCCGTTGATGCCCATGGAATCGGACGGCGAACCAATCAACTTCGAGGATCCCAGCGAGGACGCTGTTTTCGGTCGCGGCAAGATCGAGGATTTCACCTGGAAAGCCATGCTCGACTTTGCCACCTGCACCGAGTGCGGGCGCTGCCAGTCTCAGTGTCCGGCCTGGAATACCGGCAAACCCCTGTCGCCCAAGCTCGTAATCATGGACCTGCGCGACCACTGGATGGCCAAGGCTCCCTACATCCTGGGAGAGAAAACAGCAGAAAAGCTGGAGGGTCTCAACCTCGAGACGACCAAAGACAAGAGCCGCCATGTGCCGGAATCCGGATTCGGCCGGGTGCCTGGACACGGGCCCGAACAGGCGACTCGTCCGTTGGTCGGCACTGCCGAACAAGGCGGAGTGATCGATCCCGACGTGCTGTGGTCCTGTGTCACCTGCGGCGCCTGTGTCGAGCAGTGTCCGGTTGATATTGAGCACATAGATCACATTATTGATATGCGTCGCTACCAAGTAATGATGGAGTCAGAGTTCCCCTCCGAGTTGTCCACGTTGTTCAAGAACCTGGAAACCAAGGGCAACCCGTGGGGACAAAACGCTGGAGATCGGACCAACTGGATCGACGAGGTCGATTTCGACGTACCGGTCTACGGGGAGGACGTTGACAGCTTCGACGGCTACGAATACCTGTTCTGGGTCGGCTGTGCCGGAGCCTACGACGACAAAGCCAAGAAGACCACTAAAGCCGTCGCCGAACTGCTGGCCATCGCCGGGGTAAAGTACCTGGTGCTAGGCACCGGCGAAACGTGCAACGGCGACTCGGCGCACCGCTCGGGCAACGAATTCCTGTTCCAACAGCTGGCCGCCCAGGCCGTCGAGATCCTGGATGGGCTTTTCGAGGGTGTGAATAGCGTCGACCGCAAGATTGTCGTCACCTGCCCGCACTGCTTCAACACTATCGGCAAGGAATATCGACAACTGGGCGGCAACTACACTGTGCTGCACCACACTCAGCTGCTCAACTGGCTAGTGCACGACAAAAAGCTGGTCCCGGTCACGCCGGTGTCCCAAGACATCACCTACCACGACCCGTGCTATCTAGGCCGGCACAACAAGGTGTACGAGGCCCCGCGTGAACTGGTCAGGGCCGCGGGAGCCAACTTCACCGAAATGCCACGGCACGCCGAGCGCAGCTTCTGCTGCGGCGCAGGAGGCGCGCGTATGTGGATGGAAGAGCACATCGGCAAGCGGATCAACCACGAACGCGTCGACGAGGCGCTAGCCACCAACGCCACCACGATCGCCACCGCGTGCCCGTTCTGTCGGGTGATGGTCACCGACGGTGTCAACGACCGGCAGGAAGAAGCCGGTCGCAGCGGCGTCGAGGTGCTTGATGTGGCCCAGGTACTACTCGGCTCACTCGACTACGACAAGGCGAAACTGCCGGCGAAGGGCACGGCCGCAGCAGAGATCACCAAAACTGCCGGACTTTCCCCCGCCAAACCCACTGAGTCTGAGGCGCCAGCGCCGGAGAAGAGCACCCAAGCTGCAGCATCAGCCGCACCCGCCAAAGGAATAAGACTGGCCGCCGGAGCCAAGCAACCTGACGCCAAAAAACCAGTATCTCAAACCACGTCAGCTAAAGCAACCGAGGCACCGGCTGCCACAGTACCCGTTAAGGGGCTCGGTATAGCTGGTGGCGCCAAGCGACCCGGAGCGAAAAAAAGCCCTGACCAAGCCGAAACTCCCGCACCCACCGAGTCGAAATCGGAAGCAAAGCCGGAACCGTCTGACCATGCCGATGGCAACCCGGCTCCGCCAACCGCGCCCGTCAAAAGGCTGGGCATCACACGGAGCGCACGTCCGCCGGGCAAGCACTGACCAAGAGA

Protein Sequence 

>ML2501_ML2501_protein
ADADQNGARPEYDRGRAAVRGTSRLVAIQADHVRSTGQRTHRRARHPNLDANHRGLRATATVAVVTARFDALIHHVGLLHLTYGLHRGLRRAIPAELPPPDHRPLERDRLPSGLFCASCTD_HRHVRDYPHA_RAKRIRPQVPLLRIPYRRCVVDPVHDLQRDLDVCRFSWGIGRCTRRGVPLQQRRILLARHSRSAVSVGSRC_PDHRNRCAVAAHRRHAGLPADRAALQTPAHFPSADQRHV_TAARRAGPVDAHGIGRRTNQLRGSQRGRCFRSRQDRGFHLESHARLCHLHRVRALPVSVSGLEYRQTPVAQARNHGPARPLDGQGSLHPGRENSRKAGGSQPRDDQRQEPPCAGIRIRPGAWTRARTGDSSVGRHCRTRRSDRSRRAVVLCHLRRLCRAVSG_Y_AHRSHY_YASLPSNDGVRVPLRVVHVVQEPGNQGQPVGTKRWRSDQLDRRGRFRRTGLRGGR_QLRRLRIPVLGRLCRSLRRQSQEDH_SRRRTAGHRRGKVPGARHRRNVQRRLGAPLGQRIPVPTAGRPGRRDPGWAFRGCE_RRPQDCRHLPALLQHYRQGISTTGRQLHCAAPHSAAQLASARQKAGPGHAGVPRHHLPRPVLSRPAQQGVRGPA_TGQGRGSQLHRNATARRAQLLLRRRRRAYVDGRAHRQADQPRTRRRGASHQRHHDRHRVPVLSGDGHRRCQRPAGRSRSQRRRGA_CGPGTTRLTRLRQGETAGEGHGRSRDHQNCRTFPRQTH_V_GASAGEEHPSCSISRTRQRNKTGRRSQAT_RQKTSISNHVS_SNRGTGCHSTR_GARYSWWRQATRSEKKP_PSRNSRTHRVEIGSKAGTV_PCRWQPGSANRARQKAGHHTERTSAGQALTKR

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML2501 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

100 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML2501

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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