eccE3
mL2527c
ESX CONSERVED COMPONENT ECCE3. PROBABLE TRANSMEMBRANE PROTEIN.
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3009264 – 3010283
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2527c_eccE3_dna
ACCACCCCGTGAGTGCGCACCGATCACGCCCGGCTGCTATGTGGCCGGGCAGCAGCCGGATTACGCTGGCGCTGCTGGCCGTCATGCCCGCGCTTATGGCGTACCCTTGGTGGTTCACTCGCAGCTACTGGTTGCTTGGCATCGTCGCGCTTGTCGTAGTCGTGTTGTTTGGCTGGTGGCGGGGGCTGTACTTGACCACCATCTTGCGACGACGACTGGCGATGATGTGGCGCCGTGGTCGGCCAGTCAGCGCATCCGGCTCTGCTACGCGGACAACCGTGCTGCTGCGGCTGGGGCCACCGGTCGGCGGTTCAGACGTGATTCCGCTGCCGTTGATTACCCGGTACCTAAACTGCTATGGCATCCGTGCCGACAGTATTCGAATAACCAGCCGCAACAACGAATCCGACGGTGCACTGTGCGAGACCTGGATAGGGTTGACAGTGTCGGCGGCCAAAAACCTGGCGGCGTTGCAGGCGCGTTCATCGCGGATCCCGTTGCAGGAGACTGCCCAGGTCGCGGCGCGTCGGCTCGCTGACCACCTTCGTGAAATCGGTTGGGAGGTCAGCTTGGCCGTGCCGGATGGTATCCCGCGGTTGATCACGGCTGCCGGTGACGAGACGTGGCGCGGGATGCAGCAAGGCTCAGACTACCTTACCGCCTACCGGGTCAATGTCGATGACGAATTGCCTGGCACGTTGGATGCGGTCCGGTTATACCCAGCGCGCGAGACTTGGACGGCGCTAGAGATCGCCTGCCCCGACTCCTCAAGTAACCGCAACACCATTGCAGCTGCGTGTGCGTTTCTCACCGATACGGCTCCACAAGGGGCCGCACCATTGGCAGGATTGACCCCGCAACATGGAAATCACCGGCCGGCGCTGGCAGTGTTGGATTTGTTCTCCGCTCAACGACTTGACGGACACACGGATACGGACGCCGACTTGCTGACCCGGCTCCGCTGGCCCGCTCCTGCGGCAGGGGTTTCATCGTGCACCGCGACCCGAAGCCCAGCCGTTT

Protein Sequence 

>ML2527c_EccE3_protein
TTP_VRTDHARLLCGRAAAGLRWRCWPSCPRLWRTLGGSLAATGCLASSRLS_SCCLAGGGGCT_PPSCDDDWR_CGAVVGQSAHPALLRGQPCCCGWGHRSAVQT_FRCR_LPGT_TAMASVPTVFE_PAATTNPTVHCARPG_G_QCRRPKTWRRCRRVHRGSRCRRLPRSRRVGSLTTFVKSVGRSAWPCRMVSRG_SRLPVTRRGAGCSKAQTTLPPTGSMSMTNCLARWMRSGYTQRARLGRR_RSPAPTPQVTATPLQLRVRFSPIRLHKGPHHWQD_PRNMEITGRRWQCWICSPLNDLTDTRIRTPTC_PGSAGPLLRQGFHRAPRPEAQPF

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EccE3 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

4 show intermediate predicted evidence for PPIs

53 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EccE3

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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