mycP3
mL2528c
PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3010280 – 3011707
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2528c_mycP3_dna
CGGTATCGATGATGCGGTCTGAACTTCGAATTGGGCTAGCCGGTATCGCAACGACTCTGGTCGTCTTCCAAGCAACATTGTTGCGAGGCTGTCCGTGGGCACTCGCAATCAGTCCGCCGGTAGTCGATCCAGGTGTACCACCGCCGAACGGCGCACCGGGACCCGTGCAGATAATGCAACAACGCGGCTCATGTATCACTTCCGGAGTCATCCCCGGCACCGATCTAGGTATCGTCACATCCAGTCAATCGATGCTGAATCTTCCTGCAGCCTGGCAGTTTTCCCGCGGCGAGGGTCAATTGGTGGCGATCGTCGATACTGGGGTACGGCCAGGACCGCGACTGCCCAACGTCGAGGCCGGCGGCGACTATGTGGAATCGAGCGACGGCTTGACCGATTGCGACGGGCACGGAACCCTGGTCGCTGGGATAGTCGCCGGCCAACCCGCTCCTTCTGGTGAGGACGGTTTTTCGGGTGTCGCACCCGCGGCGCGATTGCTGTCCATCCGGGTGACCTCCGCCAAGTTCTCACTGCGATCGCTAGGTGGCGATCCACAGCTTAAGCAGGCGTCCCTCGAGGTGACCAGGCTCAGCCGAGCTATTGTACATGCTGCAGACCTCGGTGCGCGGGTGATTAACATCTCTGCGATAACTTGCTTGCCCGCCGATCGGTCCATTGACCAGTCCGGGCTTGGTGCTGCGATCCGCTATGCGGCAGTGGACAAGGATGCCCTGCTCGTGGCTCCGGCGGGCAATGCCGGGTCGACCGGAACGGTTGGTGGTAACATGAACTGCGAGTCCAACCCACTCACTGACCTGGGCCGCCCGGACGATCCGCGGAACTGGGCGAGCGTCACCTCGGTCTCCATTCCGTCGTGGTGGCAGCCATACGTGCTATCGGTGGCGTCGCTGACACCGAGTGGGCGGCCATCGAAATTCACTATGGCCGGGCCGTGGGTGGGTATTGCGGCGCCGGGCGAAAATATTGTTTCGGTGAGCAACCGTGACAGTGGAGATCTGGCTAACGCCCTGCCTAACGATCGGGACCAACAGATCGCGCTGAACGGCACCAGCTATGCTGCCGGCTACGTCTCGGGAGTCGCGGCGTTAGTTCGCAGCAAATATCCGGAACTGACCGCTAAACAGGTGATGCGCCGTATAACCGCGACTGCGCACACCGGTGCCCGGACGCTCTCCAACGTCGTTGGCTCCGGTACTTTGGATTCTGTGGCAGCACTGACCTGGGACCTGCCCGCAACCAACGACTCGCCGCCAGTCCCAGTAAAGCTGGTTACTGTACCGCCGCCGCCAGCACCGAAGGACAACACGCCGCGAAACGTTGCATTTGCCGGGACTGCCACATTGGTTATGGTGGTCGCGGCCGTAGTCGGGACTGCCACGATTGCTGCGCGTCGCCGAGAGGGTACCA

Protein Sequence 

>ML2528c_MycP3_protein
RYR_CGLNFELG_PVSQRLWSSSKQHCCEAVRGHSQSVRR_SIQVYHRRTAHRDPCR_CNNAAHVSLPESSPAPI_VSSHPVNRC_IFLQPGSFPAARVNWWRSSILGYGQDRDCPTSRPAATMWNRATA_PIATGTEPWSLG_SPANPLLLVRTVFRVSHPRRDCCPSG_PPPSSHCDR_VAIHSLSRRPSR_PGSAELLYMLQTSVRG_LTSLR_LACPPIGPLTSPGLVLRSAMRQWTRMPCSWLRRAMPGRPERLVVT_TASPTHSLTWAARTIRGTGRASPRSPFRRGGSHTCYRWRR_HRVGGHRNSLWPGRGWVLRRRAKILFR_ATVTVEIWLTPCLTIGTNRSR_TAPAMLPATSRESRR_FAANIRN_PLNR_CAV_PRLRTPVPGRSPTSLAPVLWILWQH_PGTCPQPTTRRQSQ_SWLLYRRRQHRRTTRRETLHLPGLPHWLWWSRP_SGLPRLLRVAERVP

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding MycP3 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

39 show weak predicted evidence for PPIs

View all pooled AlphaFold results for MycP3

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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