eccD3
mL2529c
ESX CONSERVED COMPONENT ECCD3. PROBABLE TRANSMEMBRANE PROTEIN.
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3011718 – 3013175
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2529c_eccD3_dna
TACCAAGTATGGTGTACGTCTTTGCAGAAGAATTTTGCGAGGGCCCGGTGACGTCCGGTGCCGTCATGCCGATAGTCCGCGTCGCCATTCTCGCGGACAGCCGGTTGATAGAAATGGCTCTGCCCACCGAATTGCCGTTGCGCGAAATCCTTCCCGCGGTAAAGCGTTTGGTGGTTCCTGCAGCGTCGGATAATGATTCTCCGCTGGCTGCCAACGCGAGTTTGCACCTGAGCCTGGCTCCCATCGGTGGAGCACCATTCAGCCTGGATGCCAGCCTGGACACCGTTGGAGTCGTCGACGGTGATCTGCTCGCATTGCAGCCGGTGCCAGTCGGTCCGGCGGCGCCCGGTATTGTCGAGGATATCGCCGATGCCGCGATGATCTTCTCGACAGCCCGGCTACAGTCGTGGGGCCCGACGCATATTCGACGCGGGGCCCTGGCCGCGACGACCGCTGTGACCTTTGCGGCAACTGGGCTGGGTGTCACCTATCGGGCAGTCACCGGTGCGTTGACCGGATTGCTCGTGGTCATTGTGATCGCGGTGCTCATCGCATTGGGTGGTTTGGTCCTTAGGTCACGTGCGGCGCGCACTGGGTTGGTACTGTCGATCGCAGCGCTGGTACCCATTGGTGCCGTCTTTGCGCTGGCGGTACCCGGCATATTCGGGCCAGCGCAGGTGTTGTTAGCCTCCGCCGGCGTTACCGCGTGGTCGCTAATTGCTCTGATCGTTCCTGGTCCTGAACGCGTGCGGATCGTTGCCTTTTTCACTGCTACTGTGGTGATCGGGGTTGCTGTGATGCTGGAGGCCGGCGCTGCATTGCTCTGGCAGCTAACGCCATTGACCATTGGCTGTGGCTTGATTCTGGCTGCTTTGCTGGTTACTGTCGAGGCGGCTCAGCTCTCCGCATTGTGGGCGCGGTTCCCATTGCCTGTGATCCCGGCACCGGGTGATCCGACCCCGTCGGCGCCGTCGTTTCAGGTGCTTGAGGACTTGCCGCGTCGGGTGCGCATCAGCTCTGCTCATCAGAGCGGTTTTATCGCCGCCGCCACGTTGCTCAGCATGCTAGGCTCGGTGGCGATCGCATTGCGTCCTGAGGCGGTGAGCAGTGTGGGCTGGTACTTGGTAGCCGCAACCGCGGTTGCCGCTACACTGCGTGCCCGGGTGTGGGATTCGGTCGCCTGTAAAGCCTGGTTGCTTGCCCAGCCGTATTTGGTCGCCAGCGTGCTGCTGGGGCTTTACACCGCTACGGGACGTTACGTCGCTGCTTCCGCTGCGCTGCTGGTGCTTGTCGTGGTTGTGTTGGCATGGGCGGTGGTCGCACTCAACCCGCGGATCGCCTCGTCGGATAGCTATTCGCTGCCATTGCGCCGTCTGCTTGGCATGGTCGCCTCCGGTCTTGATGCTTCACTGATCCCCGCCATGGCCTATCTGGTTAGTCTTTTCAGCTGGGTACTCA

Protein Sequence 

>ML2529c_EccD3_protein
YQVWCTSLQKNFARAR_RPVPSCR_SASPFSRTAG__KWLCPPNCRCAKSFPR_SVWWFLQRRIMILRWLPTRVCT_AWLPSVEHHSAWMPAWTPLESSTVICSHCSRCQSVRRRPVLSRISPMPR_SSRQPGYSRGARRIFDAGPWPRRPL_PLRQLGWVSPIGQSPVR_PDCSWSL_SRCSSHWVVWSLGHVRRALGWYCRSQRWYPLVPSLRWRYPAYSGQRRCC_PPPALPRGR_LL_SFLVLNACGSLPFSLLLW_SGLL_CWRPALHCSGS_RH_PLAVA_FWLLCWLLSRRLSSPHCGRGSHCL_SRHRVIRPRRRRRFRCLRTCRVGCASALLIRAVLSPPPRCSAC_ARWRSHCVLRR_AVWAGTW_PQPRLPLHCVPGCGIRSPVKPGCLPSRIWSPACCWGFTPLRDVTSLLPLRCWCLSWLCWHGRWSHSTRGSPRRIAIRCHCAVCLAWSPPVLMLH_SPPWPIWLVFSAGYS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EccD3 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

7 show intermediate predicted evidence for PPIs

59 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EccD3

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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