eccC3
mL2535c
ESX CONSERVED COMPONENT ECCC3. POSSIBLE MEMBRANE PROTEIN.
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3016454 – 3020443
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2535c_eccC3_dna
GAGCACCGATGAGTCGACTTATCTTCGAAGCTCGTCGGCGGCTACCGCCACCCAGTAGCCGCAAGGGTACCATCCTCATCGAGGCGCCTTCTGAATTGCCTCGTGTGATTCCGCCGTCGCTCCTGCGGCGTGCGATGCCCTACATGATCGTGATCCTGATCGTCGGCATGATCATCGCGATGGTCGCCACCGGGATGCGGATCATCTCCCCCCAGACATTGTTCTTTCCATTCGTGATGTTGTTGGCGGCGACCGCGCTCTATCGCGGCAACGACAACAAGATGAGCACCGAGGAGGTCGACGCCGAACGGGCTGATTACCTGCGATACTTGTCGGTGGTCCGAGACAACATCCGGAACCAGGCCGCTGAGCAGCGCGCGGCCGCACAGTGGTCCCACCCTGAGCCGACGGCGTTGGCAGGCGTGCCCGGATCCCGCCGTCAGTGGGAGCGAGACCCGCATGACTCCGACTTCCTGCTTGTGCGGGTCGGGCGGCGCCAAGTGCCGCTGGACGCCGCGCTGCGGGTCAAAGACACTGCGGACGAGATTGACCTGGAGCCGGTGTCGTATAGCGCATTACGTAGTCTGCTCGATGTCCACCGCATCGTTCGTGACGTGCCGACCGGAATTGATCTGAGCAAAGTTTCGCGGATTACGGTATTTATTGACACTGAGAGCTCCAAGGATGAAGCGCGTGCGGCGTTGCGCGCTTGGATTGCTCAGGCAGTGACCTGGCACGATCCGGCGTTGCTTGGGGTGGCGCTGGCCACTCGCGATCTGGAGAGCAGCGATTGGTCCTGGCTTAAATGGTTGCCACACGTCGACATTCCCGGTCAGCTTGATGGTGTCGGCTCGGCGCGTTACTTATCGACCGACCCCGACGAGCTGGTCTCACTGCTGGGAGCTGCGCTTACCGACCGCCCTGCGTTCACTGGCATGTCGGTTGATGCGCTGCGTCACCTGATGATAGTGATCGATGAACCCGACTACGATTTAAATGCCTCAACTTTGGTGATGGGCCGCGCCGGGGTTACGGTGGTGCATTGCTCTACCACACCGCCGCACCGCGAACAGTATTCGGATCCCGATCAGCCGATACTGCGTATTGTGCGTGGCACCATCGAACGTTGGCAGACCGGAGGCTGGCAGCCCTACATCGACACCGCTGACCGACTTGGCGCCCACGAGGCCGCCCACCTGGCCCGCCAGCTGTCACGGTGGGACTCCAACCCTACACACGCCGGGTTGCGCTCTGCGGCCACCCGCGGCGCCAGCTTCACGACGCTGCTGGGAATCCCGGATGCGTCACGGCTGGATGTGACCACACTGTGGGCTCCTCGACGCCGCGACGACGAGCTACGCATACCGATCGGTGTTACAGGCACCGGCGAGCCGTTGATGTTTGATCTCAAGGACGAAGCCGAGGGCGGTATGGGTCCGCACGGCCTGATGATCGGGATGACAGGATCCGGTAAGTCGCAGACTCTGATGTCGATTCTGTTGTCGCTGTTAACAACTCACTCGGCAGACCGGCTGATCGTGATCTATGCAGATTTCAAGGGTGAGGCTGGTGCCGACAGCTTCCGAAATTTCCCACAGGTTGTCGCGGTGATCTCGAATATGGCTGAGAAGAAGTCGCTGGCCGAAAGGTTCGCTGATACACTTCGCGGTGAGGTGGCCCGTCGGGAGACGCTGTTACGTGAGGCCGGCCGCCGGGTTCAGGGTAGTGCGTTCAACTCGGTGCTCGAATATGAGAACGCAATAGCTGCCGGCGCAGTCGATCTGCCGCCGATTCCAACACTATTTGTGGTTGCAGACGAGTTCACCCTGATGTTGGCCGATCATCCGGAGTACGCGGAGCTGTTCGACTACGTTGCACGCAAGGGCCGCTCGTTCCGGATTCATATCTTATTCGCTTCTCAGACGTTGGACTTCGGCAAAATCAAAGACATCGACAAGAATACTTCATACCGAATTGGGTTGAAGGTGGCCAATGCCAGCGTTTCCCGTCAGATCATCGGTGTGGAGGACGCTTATCACATCGAGTCGGGAAAAGAACACAAGGGCATGGGCTTTTTGGTACCGTCCCCGGGCGCAGCGCCGATTAAGTTCCGCAGCACCTACGTCGACGGTATCTACGAGCCTCCACGATCAACCAAGGTTCGGGTGGTGGAAGTTACTCCAGAACCAAAGCTGTTCACTGCCGGTGTGGTGGAGCCGGATCACCCCATCGTCATCTCCAGTGAAGACGAGGATGAGTCGGTAGCCCCGCCGCGCAAGCTGATAGCGACAATCGGCGAACAGTTGGCGCGCTACGAGCCCCGGGCGCCGAAGCTATGGCTGCCACCGCTTGACGAGTCGATCCAGCTGACTGCGATACTAGCCAGTGCCGAAGTGCCGCAACGGCAGTGGCGCTGGCCGCTCGGCGAGATTGACAAGCCTTTTGAAATGCGTCGTGACCTTTTGATGTTTGATGCTAACTCGTCTGCCGGTAATATGGTGATCCACGGCGGTCCAAAATCCGGAAAATCGACTGCGTTGCAGACATTTATCTTATCAGCAGCGAGTCTGCATTCGCCGCGTGATGTGACGTTCTACTGCTTGGACTATGGTGGAGGACAGTTGCGAGCGATTCAGGATCTGCTGCACATCGGTAGCGTTGCGTCGGCTCTAGAACCCGAACGAATCCGTCGTACCTTTGGTGAGCTTGAGCAGCTGCTGCTATCACGGCAACAGCGGGAGGTATTCCGGGACAAGCGGGCCAGTGGTTCGGCTCCAGATGACTGTTTCGGCGATGTCTTTCTCGTCATCGACAACCTCTACGCTTTCGGGCGCGACAATACGGATCAGTTCAATACCCGTAACCCGTTGCTGGCCAAGGTAACTGAGCTCGTCAATGTCGGACTGGCATACGGAATACATGTGATAATCACTACCTCGAGCTGGCTAGAGGTGCCGCTGGTGATGCGAGACGGGTTCGGTTTGCGATTAGAGCTCAAGCTGCCCGATGCCCGGGACAGCAACGTGCGCGTGGTTGGTGCACTACGTCGCCCGGCCGACGCTGTCCCGCACGATCAGCCTGGTCGCGGGTTGACTATGGCCGCCGAACATTTTTTATTCGCTGCTCCGCAGCTAGACCAGGTTGCCGTGATCAATGCTCGCCACGCCGGTGTGGCTGCGCCACCGGTGCGGTTGCTGCCCGCCAACCTTGCGCCCGATGCTGTTGGTGCACTCTATCGAGGCCCGGAACAAGTTGTAATCGGCCAGCGTGAAGAGGATCTGGCACCGGTTGTTGTTGACTTTGCCAACAATCCATTGTTAATGGTGTTTGGCGACAGTAAATCTGGTAAGACCACGCTGCTGCGCCACATCATCCGCACGATCCGCGAACATTCTTCCCCCGACCAGGTAGCGTTTATTGTGCTGGATCGGCGGCTGCACCTCGTGGACGAGCCACTATTTCCCGACAATGAATACACCGCCAACATCGACAGGATCATCCCGGCGATGCTTGGGCTGGCCAATCTCATCGAAGCGCGCCGGCCACCGGTAGGTTTGTCGGCAGCGGAATTGTCCCGCTGGGCATTTGCGGGCCACATCCATTACTTGCTCATCGACGACGTCGACCAGGTGCCGGATTCACCAGCGATGAGCGGTCCATATATCGGACAGCGGCCGTGGACCAACCTCATCGGGCTGCTTGGTCAGGCCGGTGATTTGGGGCTGCGGGTGATCGTCACAGGGCGTGCCACCGGATCGGGGCACGCGCTGATGACCAACCAACTGCTGCGTCGCTTGAACGACCTGCAGGCAACTACGCTGATGTTAGCGGGCAATCCGGCCGACAGTGGCAAGATCCGGGGCCAGCGATTTAGCCGATTGCCGGCCGGACGGGCGATTCTGCTGAGCGACAGCAATAGCCCGACGTATGTACAGTTGGTCAACCCGTTGGCCGGAGAGTCGGTACCAGAACGGGTCAACGATGGTGGAT

Protein Sequence 

>ML2535c_EccC3_protein
EHR_VDLSSKLVGGYRHPVAARVPSSSRRLLNCLV_FRRRSCGVRCPT_S_S_SSA_SSRWSPPGCGSSPPRHCSFHS_CCWRRPRSIAATTTR_APRRSTPNGLITCDTCRWSETTSGTRPLSSARPHSGPTLSRRRWQACPDPAVSGSETRMTPTSCLCGSGGAKCRWTPRCGSKTLRTRLTWSRCRIAHYVVCSMSTASFVTCRPELI_AKFRGLRYLLTLRAPRMKRVRRCALGLLRQ_PGTIRRCLGWRWPLAIWRAAIGPGLNGCHTSTFPVSLMVSARRVTYRPTPTSWSHCWELRLPTALRSLACRLMRCVT____SMNPTTI_MPQLW_WAAPGLRWCIALPHRRTANSIRIPISRYCVLCVAPSNVGRPEAGSPTSTPLTDLAPTRPPTWPASCHGGTPTLHTPGCALRPPAAPASRRCWESRMRHGWM_PHCGLLDAATTSYAYRSVLQAPASR_CLISRTKPRAVWVRTA__SG_QDPVSRRL_CRFCCRC_QLTRQTG_S_SMQISRVRLVPTASEISHRLSR_SRIWLRRSRWPKGSLIHFAVRWPVGRRCYVRPAAGFRVVRSTRCSNMRTQ_LPAQSICRRFQHYLWLQTSSP_CWPIIRSTRSCSTTLHARAARSGFISYSLLRRWTSAKSKTSTRILHTELG_RWPMPAFPVRSSVWRTLITSSREKNTRAWAFWYRPRAQRRLSSAAPTSTVSTSLHDQPRFGWWKLLQNQSCSLPVWWSRITPSSSPVKTRMSR_PRRAS__RQSANSWRATSPGRRSYGCHRLTSRSS_LRY_PVPKCRNGSGAGRSARLTSLLKCVVTF_CLMLTRLPVIW_STAVQNPENRLRCRHLSYQQRVCIRRVM_RSTAWTMVEDSCERFRICCTSVALRRL_NPNESVVPLVSLSSCCYHGNSGRYSGTSGPVVRLQMTVSAMSFSSSTTSTLSGATIRISSIPVTRCWPR_LSSSMSDWHTEYM__SLPRAG_RCRW_CETGSVCD_SSSCPMPGTATCAWLVHYVARPTLSRTISLVAG_LWPPNIFYSLLRS_TRLP_SMLATPVWLRHRCGCCPPTLRPMLLVHSIEARNKL_SASVKRIWHRLLLTLPTIHC_WCLATVNLVRPRCCATSSARSANILPPTR_RLLCWIGGCTSWTSHYFPTMNTPPTSTGSSRRCLGWPISSKRAGHR_VCRQRNCPAGHLRATSITCSSTTSTRCRIHQR_AVHISDSGRGPTSSGCLVRPVIWGCG_SSQGVPPDRGTR__PTNCCVA_TTCRQLR_C_RAIRPTVARSGASDLADCRPDGRFC_ATAIARRMYSWSTRWPESRYQNGSTMVD

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EccC3 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

13 show intermediate predicted evidence for PPIs

114 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EccC3

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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