eccB3
mL2536c
ESX CONSERVED COMPONENT ECCB3. POSSIBLE MEMBRANE PROTEIN.
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3020440 – 3022098
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2536c_eccB3_dna
GGTACCGCATGACTAGTAATGAGCTGCCCGGCGAGTGGTCAGGGGAAAGGCGTTCGTTCTTCTCGCGAACGCCGGTCAACGACAATCCTGACAAGGTGGTCTACCGCCGCGGATTTGTCACCCGTCACCAAGTGACAGGCTGGCGGTTCGTTATGCGCCGGATCGCCTCCGGTATCGCTTTGCACGACACCCGAATGCTTGTCGACCCGTTGCGCACCCAGTCACGTTCGGTGCTGGTGGGCGCACTACTGGTGATTACTGGGCTGATAGGTTGCTTTGTGTTCTCATTCATCCGGCCCAATGGTGCAGCAGGTAACAACGCGGTGCTTGCCGATCGGTCTACCGCCGCACTGTATGTACGGGTGGGCGATGAGCTCCACCCGGTGCTCAACCTGACCTCGGCTAGGCTGATCGTCGGCCGGTCGGTCAACCCCATCACAGTGAAAAGCAGCGAGCTGGACCGGTTTCCGCGCGGCAATCTGATCGGTATTCCAGGAGCACCGGAGAGGATGGTGCAAAACACAACCCATGACGCGAACTGGACGGTGTGTGACGTCGTCAGTGGGGAAGGCGGGCACGCTGCTCACAGCATGGGTGTCACAGTGATCGCCGGTCCGCCGGACAGTCACGGCATGCGGGCCGCCGTGCTGGGGTCCGCGCATGGTGTCTTGGTTGATGCTCCGTCTGAGCGGGGAGGCAGCACCTGGCTGCTGTGGGACGGCAAGCGCAGCGAAATCGACTTGGCTGACCACGCAGTGACCGACGCGCTGGGGTTTGGTGTCGGTTTTGCTGAGGTGCCTGCGCCCAGGCCTATCGGGGCAGGGTTGTTCAACGCGATCCCCGAAGCGCCGCCGCTGAAGGCGCCCGTCATTCCGAATGCTGGTGCCACACCAAGCTTCGGAGTGCGCGCTCCTATCGGGGCGGTGGTGGTGTCCTTTGGTCTGGCGGCACTGGGCAAGAACCCATACGACTCGGTGCGGTATTACGCGGTGTTGCCGGACGGTCTGCAGCCTATCTCGCCGGTGCTTGCCGCGATCCTGCGCAACATCAATTCTTATGGGCTGCAGCAGCCGCCGCGGCTTGGTGCCGACGAGGTCGACAAGTTGCCGGTGTCGCGGATGCTGGACACCGAGCGTTATCCTGAACAGCAGATCAGTCTCATCGACGCTGGCTATGCCCCGGTCAGCTGCGCATATTGGAGCAAACCAGCCGGGGCCGCTACCAGCTTTCTGAGTCTAATGTCCGGCGCGGCGCTGCCAGTGCCTGATGCTGCGCGCGCTGTCGAGCTGGTTAGTGCCCCCTCCCGGGGAGATAGCTCGACGGCCAGTCGGGTTGTGCTGACACCCGGCACCGGCTACTTCGCTCAAACCGTGGGTGTTGGCTCGGCAGCGCCAGCCACCGCGTCATTGTTCTGGGTCTCCGATACCGGGGTGCGCTATGGTATTGACACCGAGGCTGATGCAAGATCGGAAGCTACCGCTGGCCCCGGCAAAATCGTTGAGGCTCTTGGCCTGAAACTACCTGCAGTGCCTATTCCGTGGTCAATATTGTCGCTGTTCGCGGTTGGACCGACGCTGTCGCGTGCCGACGCACTGCTGGAACACGATGGCTTGGCACCCGATACCAGGGCCGGTCGTACGACGACAGCATACGGGGAGC

Protein Sequence 

>ML2536c_EccB3_protein
GTA_LVMSCPASGQGKGVRSSRERRSTTILTRWSTAADLSPVTK_QAGGSLCAGSPPVSLCTTPECLSTRCAPSHVRCWWAHYW_LLG__VALCSHSSGPMVQQVTTRCLPIGLPPHCMYGWAMSSTRCST_PRLG_SSAGRSTPSQ_KAASWTGFRAAI_SVFQEHRRGWCKTQPMTRTGRCVTSSVGKAGTLLTAWVSQ_SPVRRTVTACGPPCWGPRMVSWLMLRLSGEAAPGCCGTASAAKSTWLTTQ_PTRWGLVSVLLRCLRPGLSGQGCSTRSPKRRR_RRPSFRMLVPHQASECALLSGRWWCPLVWRHWARTHTTRCGITRCCRTVCSLSRRCLPRSCATSILMGCSSRRGLVPTRSTSCRCRGCWTPSVILNSRSVSSTLAMPRSAAHIGANQPGPLPAF_V_CPARRCQCLMLRALSSWLVPPPGEIARRPVGLC_HPAPATSLKPWVLARQRQPPRHCSGSPIPGCAMVLTPRLMQDRKLPLAPAKSLRLLA_NYLQCLFRGQYCRCSRLDRRCRVPTHCWNTMAWHPIPGPVVRRQHTGS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EccB3 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

4 proteins show strong predicted evidence for PPIs

22 show intermediate predicted evidence for PPIs

46 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EccB3

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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