eccA3
mL2537c
ESX CONSERVED COMPONENT ECCA3
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3022091 – 3024013
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2537c_eccA3_dna
CTTACGCAATGCTAATTTCAGGCAGGTCAGGTTGGGCGATACTAGGTACGGGAGGCAAAGCGGCCGTGAACCGCGGTGACGCCGGCAAGCTTGGCGGGCAGTCTGTCATTGCTCGGGCGCACGTTAAGGTTGATGGCGACGTTGTTAGCCGATTCGCTACCTGTTGTCGCGCCCTCGGCCTTGCGGTCTACGACCGTCAACGTCCGGCCGACCTGGCCGCCGCTCGGTCGGGTTTCACCGCACTTGCCCGCATCGCGCATGATCAGTGTGATGTCTGGATCGGGTTAGCCGCTGCTGGTGACGTGTCCACCCCTGTACTGGCAGCGATTTCGTGTACCGCTGACACCGCGGGCATGCTGCAACGTCAGGTGGAACTGGCCCCCGCCGCGTTGGGCTTTCACTACGACACCGGACTGTACCTGCAGTTTCGAGCCATCGGTCCGGATGATTTCCATCTCGCCTATGCGGCGTCACTAGCGTCAACCGGGGGGCCCGGACCCTATGCCGAGGCCGATCAGATAGTCACCGGTATCATCGACCGCCGGCCAGGTTGGCGGGATGCCCGTTGGGTCGCTGCCGTCATCCACTACCGCGCCGGGCGCTGGTCGGATGTCGTCAAGCTGTTGACTCCGATCGTGAATGACCCTGATATCGACGAGGCTTACACGCACGCCGCCAAGATTGCATTGGGTACCGCGCTGGCCCGGCTGGGTATGTTCGCCCCGGCATTGTCGTATCTGGAGGAGCCAGCGGGCCCGGTCGCGGTGGCGGCTGTCGATGGCGCGTTAGCCAAAGCGCTGGTGCTACGTGCGCACACGGACGAGGAGTCGGCCAGCGAAGTTCTGCAAGATTTGTACGCGGCACATCCGGACAACGAGCAAATTGAGCAGGCCCTGTCCGACACTAGTTTTGGGATCGTTACCACTACCGCGGCCCGGATCGATGCTCGCACCGATCCATGGGATCCCGAGACCGAACCTGGTGTGGAAGATTTCATCGACCCCGCAGCCCACGAACGCAAAGCCGTGCTGCTTCATGAGGCCGAGCGCCAGCTCGCCGAATTCATCGGCCTGGATGAGGTCAAAAACCAGGTGTCACGGCTGAAGAGTTCGGTGGCTATGGAGCTAGTGCGTAAGCAGCGTGGGCTCATGGTAGCGCAACGTGCCCACCACCTCGTCTTTGCTGGCCCACCTGGGACAGGCAAGACCACAATCGCCCGTGTGGTCGCCAAAGTTTATTGTGGCCTAGGCCTTTTGAAGAAAGAGAATATCCGAGAAGTGCATCGCGCCGACCTTATCGGCCAGCACATCGGTGAGACCGAGGCCAAAACCAACGCGGTCATCGACAGTGCACTAGACGGAGTGTTGTTTCTTGACGAAGCCTACGCCCTAGTGGCTACGGGCGCTAAAAACGACTTCGGTTTGGTGGCCATCGACACTTTGCTGGCACGGATGGAGAACGATCGTGACCGGCTAGTCGTGATCATCGCCGGCTACCGCGCCGATCTGGATAAGTTCCTGGACACTAACGAAGGCTTGCGGTCGCGGTTCACCCGTAATATCGATTTTCCTTCATACGCATCGCATGAGTTGGTCGAGATCGCGCACAAGATGGCCGAACAGCGAGACAGCGTCTTCGAGCAGGCTGCGCTCGACGAGTTGGAGGTTCTGTTCGCTAATTTGGCGACATCGTCTACCCCTGACTCCAATGGAATCTCTCGGCGCAGCCTCGACATCGCGGGCAACGGGCGGTTTGTCCGCAACATCGTTGAACGTTCAGAAGAAGAACGTGAATTCCGGTTGGACCATTCGAACAATGTCGGTACTGGTGAGTTAAGTGACGAGGAACTCATGACCGTAACGTCCGAGGATGTACGGAGATCGGTAGAGCCGTTGCTGCGCGGTCTCGGACTTATGGTACCGC

Protein Sequence 

>ML2537c_EccA3_protein
LTQC_FQAGQVGRY_VREAKRP_TAVTPASLAGSLSLLGRTLRLMATLLADSLPVVAPSALRSTTVNVRPTWPPLGRVSPHLPASRMISVMSGSG_PLLVTCPPLYWQRFRVPLTPRACCNVRWNWPPPRWAFTTTPDCTCSFEPSVRMISISPMRRH_RQPGGPDPMPRPIR_SPVSSTAGQVGGMPVGSLPSSTTAPGAGRMSSSC_LRS_MTLISTRLTRTPPRLHWVPRWPGWVCSPRHCRIWRSQRARSRWRLSMAR_PKRWCYVRTRTRSRPAKFCKICTRHIRTTSKLSRPCPTLVLGSLPLPRPGSMLAPIHGIPRPNLVWKISSTPQPTNAKPCCFMRPSASSPNSSAWMRSKTRCHG_RVRWLWS_CVSSVGSW_RNVPTTSSLLAHLGQARPQSPVWSPKFIVA_AF_RKRISEKCIAPTLSASTSVRPRPKPTRSSTVH_TECCFLTKPTP_WLRALKTTSVWWPSTLCWHGWRTIVTG_S_SSPATAPIWISSWTLTKACGRGSPVISIFLHTHRMSWSRSRTRWPNSETASSSRLRSTSWRFCSLIWRHRLPLTPMESLGAASTSRATGGLSATSLNVQKKNVNSGWTIRTMSVLVS_VTRNS_P_RPRMYGDR_SRCCAVSDLWYR

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EccA3 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

11 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EccA3

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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