fadD2
mL2546c
PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3033668 – 3035314
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2546c_fadD2_dna
GGCAGGCTGTGACCAAGCTTCGGCACTACCTTGAGCGTGGCGCCGCCGAGGTACATTACCTGCGCAGCATCTTCGAATCGGGCGCGCTCGGGTTCGAGCCGCCGCTCACCTACGCCGCAATGGCCGTCGCTATGAGAAAGTGGGGCGATCTCGCCATGCTGCCGGCGATGCCGGCTAGGCGCTCTCCACACCGCGCGGCGCTCATCGACGAAGAGGGGACACTAACCTACAAGGAGTTAGACAGGGCAGCCCACGCGTTGGCCAATGGGCTAATTGCCAAGGGAGTCCGCGGCGGGGACGGCATCGCCATCTTGGCACGCAACCACCGCTGGTTTGTCATCGCGAACTACGGCTGTGCGCGAGTGGGCGCCCGCATTATTTTGCTCAATAGCGAATTCTCTGGCCCGCAAATCAAAGAGGTGTCGGAGCGCGAGGGAGCCAAGGTAATCATCTACGACGACGAGTACACCAAAGTTGTCAGCAAAGCCGAACCGGCACTCGGCAAATTGCGGGCGCTCGGCGTCAACCCAGACGAAGAGGAACCGCCGGGCAGCACCGACGAGACGTTAGCGGAGTTAATCGCGCGCAGTAGCAGCGCGCCAGCCCCGAAGGTACGTAAGCGCGCCTCGATCATCATCCTGACCAGCGGGACGACCGGCACCCCTAAGGGAGCCAACCGCAATACCCCCGCATCGCTTGCGCCACTCGGTGGCATCTTGTCGAAGGTCCCGTTCAGGGCGCACGAGGTGACGTTGCTGCCGGCGCCGATGTTCCACGCTCTGGGGTATCTGCACGCCACGCTTGCGATGTTCCTGGGGTCGACGCTGGTGCTGCGGCGCCGGTTCAAGCCGGCGACAGTGCTCGAAGACATCGAAAAACACCAGGCAACAGCCATGGTTGTGGTGCCGGTCATGCTGTCGCGGATCCTCGACACGCTCGAGAACTTGGAGACCAAGTCCGATTTGTCCAGCTTGCGTGTCGTGTTCGTATCTGGATCGCAACTGGGTGCCGAACTAGCCACACGCGCGCTCGAGGAACTCGGCCCCGTCATCTACAACATGTACGGTTCGACCGAGATCGCGTTTGCCACGATAGCAGGACCCAAGGACCTGCAAATCAACTCGGCGACAGTTGGTCCGGTAGTTAAGGGCGTCAAGGTTAAGATCCTTGACGATAGCGGCAAAGAAGTGCCGCGAGGCCAGGTTGGTCGGATCTTCGTAGGGAACGCCTTCCCATTCGAGGGTTACACTGGCGGCGGTGGCAAGCAGATTATCGATGGCCTGTTATCGTCGGGCGACGTCGGCTACTTCGATGAGCATGACTTGCTGTATATCAGTGGCCGTGACGATGAGATGATCGTTTCCGGCGGCGAGAACGTGTTCCCTGCCGAAGTCGAGGATCTGATCAGCGGGCATCCTGAAGTGGTGGAGGCCACCGCGATCGGTGTTGACGACAAGGAGTGGGGCGCTCGGCTGCGTGCATTCGTGGTAAAGAAGCAGGACGCCACTATTGACGAGGACGCGATCAAAGCCTACGTTCGCGATCACTTGGCCCGCTACAAGGTGCCGCGAGAAGTGATCTTCCTCGAAGAGCTACCGCGTAACCCCACCGGCAAGGTCCTCAAGCGCGAACTCCGCGATTTCGAGG

Protein Sequence 

>ML2546c_FadD2_protein
GRL_PSFGTTLSVAPPRYITCAASSNRARSGSSRRSPTPQWPSL_ESGAISPCCRRCRLGALHTARRSSTKRGH_PTRS_TGQPTRWPMG_LPRESAAGTASPSWHATTAGLSSRTTAVREWAPALFCSIANSLARKSKRCRSAREPR_SSTTTSTPKLSAKPNRHSANCGRSASTQTKRNRRAAPTRR_RS_SRAVAARQPRRYVSAPRSSS_PAGRPAPLREPTAIPPHRLRHSVASCRRSRSGRTR_RCCRRRCSTLWGICTPRLRCSWGRRWCCGAGSSRRQCSKTSKNTRQQPWLWCRSCCRGSSTRSRTWRPSPICPACVSCSYLDRNWVPN_PHARSRNSAPSSTTCTVRPRSRLPR_QDPRTCKSTRRQLVR_LRASRLRSLTIAAKKCREARLVGSS_GTPSHSRVTLAAVASRLSMACYRRATSATSMSMTCCISVAVTMR_SFPAARTCSLPKSRI_SAGILKWWRPPRSVLTTRSGALGCVHSW_RSRTPLLTRTRSKPTFAITWPATRCREK_SSSKSYRVTPPARSSSANSAISR

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding FadD2 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

21 show weak predicted evidence for PPIs

View all pooled AlphaFold results for FadD2

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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