| TN Coordinates: | 3037546 – 3038214 |
|---|---|
| Vulnerability Index (VI): |
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence
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DNA Sequence
>mL2549_ML2549_dnaAACAAGCAACCATACGCAAGAGCTATCTAAAAACTTGGTAAGGAACGATACCATTCTCAATTACGGCGATCAAGCGCTGATGCTGCAATGCGGCAGCACCTCTGATGTCCTGGCATGGGCAGATGCGTTACGTGCGGCGGCACTACCCGGTGTGGTCGACATCGTCCCAGGCGCCCGCACCGTGTTGGTGAAACTCGGCGGACCCCGCGACCAAAAGGTCACCCTTCAGCGGCTACGCAAGCTGCGGGTCACCCCGGAGGCGACTGCGCCAGCTGACCGCGGCGCCGACGTGGTGATCGACGTCGTCTACGACGGCCCGGACCTCGCCGAGGTTGCCCGCACTACCGGACTGACGGTAGCGAAGGTCATCACCGCCCATACCGGCACTCCGTGGCGGGTTGGATTCAATGGCTTCGCACCAGGTTTCGCATATCTGGTCGACGGCGATCCACGACTGCGAGTGCCACGCCGGTGCGATCCGCGGACCTCGGTGCCGCCTGGTTCGGTCGCCCTCGCCGACGAATTCAGCGCGATATATCCGCGCCAATCTCCTGGCGGTTGGCAACTCATCGGCCACACCAACACAGTGCTGTGGGACACCAACCGGCCCAATCCCGCATTGCTGACACAGGGCATGTGGGTGCAGTTCCGTGCCACGTAAAAGAATCG
Protein Sequence
>ML2549_ML2549_proteinNKQPYARAI_KLGKERYHSQLRRSSADAAMRQHL_CPGMGRCVTCGGTTRCGRHRPRRPHRVGETRRTPRPKGHPSAATQAAGHPGGDCAS_PRRRRGDRRRLRRPGPRRGCPHYRTDGSEGHHRPYRHSVAGWIQWLRTRFRISGRRRSTTASATPVRSADLGAAWFGRPRRRIQRDISAPISWRLATHRPHQHSAVGHQPAQSRIADTGHVGAVPCHVKES
No essentiality data available for this gene.
AlphaFold Protein Interactions
Protein–protein interactions (PPIs) were predicted by co-folding ML2549 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).
1 protein shows strong predicted evidence for PPIs
7 show intermediate predicted evidence for PPIs
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