fadE5
mL2563
PROBABLE ACYL-CoA DEHYDROGENASE FADE5
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3055237 – 3057072
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2563_fadE5_dna
CTACAAAAGCAACGTTCGCGACCAGGTTTTTAACCTCTTTGAGGTGTTGGGCGTGGACAAGGCTTTCGGTACAGACGAGTTCAGCAATCTGGACGCCGACACCGCCTACGAAATGTTGACCGAGGTCAGCCGTCTGGCCGAGGGACCCGTCGCCGCGTCGTTCGCTGAAGGCGACCGCAACCCACCAGTATTCCACCCCGAAACTCACTCGATCACACTGCCGGAGTCGTTCAAGAAATCCTGCAGGGCGGTGGCCGAAGCCGGTTGGAGCAAGGCCGGCATCGACGAGGCACTCGGTGGCACGCCGATGCCCAAGGCGCTGTTATGGGCACTGCACGAGCATCTGATGGGCGCCAACCCGGCGGTGTGGATTTATGCTGGCGGTGCCGGCTTCGCTAACATCCTCTACCACCTCGGCACCGAGAAACAGAAGAAGTGGGCGGTGTGGGCTGCCGAGCGCAATTGGGGTTCGACCATGGTGCTCACCGAGCCAGATGCCGGTTCGGATGTGGGTGCCGGCCGGACCAAGGCCGTTCATCAGGAAGACGATTCCTGGCACATTGATGGGGTCAAGCGATTCATCACCTCGGGTGACTCCGACGACCTATTCGAGAACATCTTCCACCTCGTGCTGGCCCGCCCCGAGGGCGCCGGGCCTGGCACCAAGGGGCTGTCACTATTCTTCGTGCCCAAGTTCCTGTTCGACTTCGAAACCGGTGAGCTCGGCGAACGCAACGGGGTCTTCGTCACCAACGTCGAGCACAAGATGGGCCTCAAGGTGTCTGCCACTTGTGAGCTGTCCTTTGGCCAGCACGGCGTGCCCGCTAAGGGCTGGCTGGTCGGCGATGTGCACGATGGCATAGCGCAGATGTTTGAGGTCATCGAGCAGGCACGCATGATGGTCGGCACCAAGGCGATTGCTACCCTGTCGACCGGCTATCTGAACGCGCTGGAATACGCAAAGTCCCGCGTGCAGGGCGCCGACCTGACCCAAATGACCGACAAGACCGCACCGCGGGTAACCATCACGCATCACCCTGATGTGCGCCGGTCGCTAATGACTCAAAAGGCCTACGCCGAAGGTCTGCGAGCGCTGTACCTCTACACAGCCACGTTCCAGGATGCAGCAGTGGCCGAAGCGGTGCACGGCGTGGACGCCAAGCTGGCGGTCAAGATCAACGACCTGATGCTGCCGTTAGTCAAAGGGGTGGGCTCCGAGCAGGCCTACGCGAAACTCACTGAGAGCCTGCAGACCCTCGGTGGTTCGGGCTTCCTCCAAGACTACCCGATTGAGCAATACATCCGCGACGCGAAAATTGACTCGCTGTACGAAGGCACCACCGCCATCCAGGCGCAGGACTTTTTCTTCCGCAAGATCGTCCGCGACAAGGGCGTGGCACTGTCCTATGTGTCGGGACAAATCCAGCAATTCGTCGACAGCGAGACTGGTAACGGTCGGCTGAAAAGCGAACGCGAACTGCTGGCCAAGGCCCTAACCGACATCCAGGGGATGGAAGCCTCACTGACCGGCTATCTGATGGCAGCTCAGCAAGACGTCACCAGCTTGTACAAGGTGGGTCTGGGGTCGGTGCGCTTCCTAATGAGCGTCGGTGACCTGATCATCGGCTGGTTGCTGCAGCGCCAGGCCGCGGTGGCGGTGCAGGCACTCGATGCCGGCGCTAGCAGCGCTGAGCGTTCCTTCTACGAAGGCAAAGTCGCGGTGTCGTCATTCTTCGCGAAAAACTTCTTGCCACTGTTGACCAGCACTCGCGAAGTGCTTGAGGTGCTGGACAACGACATCATGGAGCTTGACGAAGCCGCCTTCTAGTAGTCGAT

Protein Sequence 

>ML2563_FadE5_protein
LQKQRSRPGF_PL_GVGRGQGFRYRRVQQSGRRHRLRNVDRGQPSGRGTRRRVVR_RRPQPTSIPPRNSLDHTAGVVQEILQGGGRSRLEQGRHRRGTRWHADAQGAVMGTARASDGRQPGGVDLCWRCRLR_HPLPPRHRETEEVGGVGCRAQLGFDHGAHRARCRFGCGCRPDQGRSSGRRFLAH_WGQAIHHLG_LRRPIREHLPPRAGPPRGRRAWHQGAVTILRAQVPVRLRNR_ARRTQRGLRHQRRAQDGPQGVCHL_AVLWPARRAR_GLAGRRCARWHSADV_GHRAGTHDGRHQGDCYPVDRLSERAGIRKVPRAGRRPDPNDRQDRTAGNHHASP_CAPVANDSKGLRRRSASAVPLHSHVPGCSSGRSGARRGRQAGGQDQRPDAAVSQRGGLRAGLRETH_EPADPRWFGLPPRLPD_AIHPRREN_LAVRRHHRHPGAGLFLPQDRPRQGRGTVLCVGTNPAIRRQRDW_RSAEKRTRTAGQGPNRHPGDGSLTDRLSDGSSARRHQLVQGGSGVGALPNERR_PDHRLVAAAPGRGGGAGTRCRR_QR_AFLLRRQSRGVVILREKLLATVDQHSRSA_GAGQRHHGA_RSRLLVVD

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding FadE5 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

22 show weak predicted evidence for PPIs

View all pooled AlphaFold results for FadE5

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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