fadA2
mL2564c
PROBABLE ACETYL-CoA ACYLTRANSFERASE FADA2 (3-KETOACYL-CoA THIOLASE) (BETA-KETOTHIOLASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3057494 – 3058867
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2564c_fadA2_dna
TAACTGATATGCTCGGAGAGACACGGAGATTACAAGTGGCCCCTGCAAGTTCTGTGGCAAGTGACAAGACTATTCAGAGGACCACGTTCGCTAAGCAAAGAGTCGCCGTGTTGGGCGGCAATAGGATCCCGTTCGCGAGATCAAATGGCGCCTATGCCGAAGCGTCCAACCAGGACATGTTCTCCGCGGCTCTAAGTGGTCTGGTGGACCGATTCGGGCTGGCCGGCGAACGATTGGACATGGTGATCGGCGGTGCTGTGCTCAAGCACAGCCGCGACTTCAACCTGATGCGTGAATGCGTGTTGGGGTCGCAACTGTCGCCATACACACCTGCGTTCGACCTGCAGCAGGCTTGTGCAACTGGTCTGCAGGCGGCGATTGTGGCAGCTGATGGCATTGCAGCTGGCCGCTATGAGGTGGCCGTTGCCGGCGGAGTCGACACCACTTCGGACGTGCCGATCAGCCTGGGTGACAACCTGCGCCGCAACCTGCTGAAGCTGCGCCGATCCAAATCCAACGTGCAACGGCTGAAGCTGGTGGGCGCATTGCCTGCCAATATCGGGGTCGAAATCCCCGCCAACAGTGAGCCCCGCACTGGGCTGTCCATGGGAGAACACGCCGCCATCACCGCCAAGAAAATGGGGATCAAGCGGGTCGATCAAGACGAGCTGGCTGCCGCTAGCCATCGCAATATGGCCTCCGCTTACGATCGGGGCTTCTTCGACGATCTGGTCACGCCGTTTCTGGGGCTCTACCGCGATGACAATCTACGGCCCAACTCTCATGTGGAAAAGTTAGCCACGTTGCGCCCGGTTTTCGGAGTTCAGGCCGGTGATGCGACGATGACGGCGGGAAATTCTACTTCGCTGACCGACGGCGCTTCGGTAGCGTTGCTCGCCACCGAGCAATGGGTTGCTGCGCATTCGTTGACCCCGTTTGCTTACTGGGTAGATGCGGAGATCGCCGCGGTTGATTACGTCAGCGGAAATGACGGCCTGCTGATGGCGCCGACTTACGCGGTACCTCGGCTGTTAGCCCGCAACGGGCTGAGCTTTCAGGATTTCGACTTCTACGAAATTCACGAGGCATTTGCCTCGGTGGTGCTGGCGCATTTGCAGGCGTGGGAGTCCGAGGAGTATTGCCGGCAGTGTCTGGGCCTCGATACCGCTCTTGGCCCGATCGACCGGTCCAAGCTCAATGTCAATGGTTCATCATTGGCTGCCGGTCATCCCTTTGCTGCCACGGGTGGACGTATCCTTGTTCAGACTGCAAAACAACTTGCTGAGCAGAAGGCAACGCAAAAAGGTTGCGGGCCGATGCGGGCTTTGATTTCGGTCTGTGCCGCCGGCGGCCAAGGTGTAGCTGTGATTCTGG

Protein Sequence 

>ML2564c_FadA2_protein
LICSERHGDYKWPLQVLWQVTRLFRGPRSLSKESPCWAAIGSRSRDQMAPMPKRPTRTCSPRL_VVWWTDSGWPANDWTW_SAVLCSSTAATST_CVNACWGRNCRHTHLRSTCSRLVQLVCRRRLWQLMALQLAAMRWPLPAESTPLRTCRSAWVTTCAATC_SCADPNPTCNG_SWWAHCLPISGSKSPPTVSPALGCPWENTPPSPPRKWGSSGSIKTSWLPLAIAIWPPLTIGASSTIWSRRFWGSTAMTIYGPTLMWKS_PRCARFSEFRPVMRR_RREILLR_PTALR_RCSPPSNGLLRIR_PRLLTG_MRRSPRLITSAEMTAC_WRRLTRYLGC_PATG_AFRISTSTKFTRHLPRWCWRICRRGSPRSIAGSVWASIPLLARSTGPSSMSMVHHWLPVIPLLPRVDVSLFRLQNNLLSRRQRKKVAGRCGL_FRSVPPAAKV_L_FW

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding FadA2 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

10 show weak predicted evidence for PPIs

View all pooled AlphaFold results for FadA2

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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