ML2570
mL2570
PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3065565 – 3069782
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2570_ML2570_dna
AATGTCGCGTTGGTGGTTGGTGTTGGTCGGGGTCGTCGCGGTGGCGTTGACGTTCGCGCAATCCCCGGGACAGATCTCCCCCGATACCAAACTGGACCTAACCACCAACCCGCTACGCTTTCTGGCCCGCGCGACCAACCTGTGGAATAGCGACCTGCCGTTTGGTCAGGTGCAGAATCAGGCCTACGGCTATCTGTTTCCGCACGGCACCTTCTTTCTCATCGGACAGCTACTGGGATCACCCGGATGGATAACCCAGCGTTTGTGGTGGGCGCTGCTGCTGACGGCCGGGTTCTGGGGACTACTCCGAGTCGCCGAGACACTGAGCATCGGCAGTCCAACTTCACGCGCGATTGGCGCGGTAGCGTTTGCGTTATCGCCACGGGTGCTGACCACACTGGGGTCGATCTCGTCGGAAACTCTGCCGATGATGCTGTCGCCGTGGGTGTTGCTGCCCACGATTCTAGCTTTGCAGGGAGCTCCGGGCAGGTCGGTGCGGACACGTGCCGCGCAGGCGGGGCTGGCGGTCGCGTTGATGGGTGCAGTTAACGCCATTGCAACGCTGGCCGGTTGTCTGCCTGCAGTGATCTGGTGGGCTTGTCACCGACCGAACCGCTTGTGGTGGCGTTATACCGGGTGGTGGCTGTTAGCACTGTGTTTGGCAACGCTGTGGTGGGTGGTGGCACTGGTTCTGCTGCACGGCGTCAGTCCCCCGTTCTTGGACTTCATCGAATCCTCCGGCGTTACCACGCAATGGTCGTCGTTAGTTGAGATGCTGCGCGGCACCGACAGCTGGACACCCTTCGTGGCACAGACCGCTACCGCGGGCACACCACTGGTCACCGAGTCGGTGGCCATCCTGGGCACCTGCCTGGTAGCGGCGGCCGGATTGGCCGGGCTGGCTAGCACTGGGATGCCGGCTCGAGGTCGGCTGGTAACGATGTTGGTAATCGGAGTGGTATTGCTATCCGCCGGCTACAGCGGTGGGTTGGGCTCGCCGCTGGCGCAGGCGGTGCAGGCGTTCCTGGACTCCAGCGGCGCAGCACTGCGCAACGTGCACAAACTGGAGTCGGTGATCCGAACCCCGTTCGCATTGGGCATCGCCGGGCTTCTGGGCCGAATCCCCCTACCGGGCAGCGCGCCGGTATTGGTGTGGCTGAGCTCGTTTGCCCACCCCGAGCGCGACAAACGAGTCGCCGCGACAGTGGCGGTGTTAACCGCACTGTTGGTCAGCACCTCGTCAGCGTGGACGGGTCGGCTCACCCCGCCAGGCACGTTCAGTGCGATACCGCAATATTGGCACGACACCAGTGACTGGCTCAGCGAACACAACACGGGAATACCGACACCTGGACGGGTGCTGGTGGTACCGGGCGCGCCGTTCGCCACTCAGGTGTGGGGCACCAGCCACGACGAGCCGCTGCAGGTGCTCGGCAATAGCCCATGGGGAGTGCGCGACTCCATCCCGCTGACTCCGCCGCAGGCTATCCGGGCGCTGGATTCGGTGCAACGGCTATTCGCCTCCGGACGCCCGTCGGTTGGCCTGGCCGATACCCTTGCCCGCCAAGGCATTTCCTACGTGGTGCTGCGCAACGATCTGGATCCCGACACGTCGCGCTCAGCTCGCCCGATCCTGGTACACCGGGCCATCGCCGGGTCACCGCAGCTGGAAAAAGTAGCGCAGTTCGGTGCACCAGTGGGCACCAACATGCTCAAAGGTTTCGTTGCCGACAGCGAATTGCGTCCCTGGTACCCAGCGGTGGAGATCTATCGGGTGGCCGTTAGTGATGGGACCAATCCCGGCAAACCCTACTTCGCCGACACCGACCAACTTCCCCGCATCGACGGCGGACCCGAAGTGCTGCTGCGTCTTGACGAACGGCGCCGACTACTGGGACAGCCTGCATTAGGTCCGGCGCTGATGACCGCAGACGCCCAGTTCGCTGGTCTGCCACTACCCAGCCGGGCCGAGGTCACCATAACCGATACCCCGGTAGCACGCGAGACCGACTACGGCCGAGTAGACCAGCACTCGTCGGCGATCCGCGCAGTTAACGACGCCCGGCATACTTTCAACCGAGTACCCGACTACCCAGTCCCTGGCGCCGAAATGGTATTCGGGGGTTGGAGCGGTGGCCGGATCACCGCGTCAAGCTCGTCATCGGATGCCACCTCGATGCCCGATGTCGCTCCGGCAACCTCACCGGCCGCCGCCATAGACGGCGACCCGGCGACCTCGTGGGTGTCCAACGCACTGCAGCCCGCCGTCGGTCAATGGCTGCAAGTCGATTTTGACCACCCGGTAAACAACGCCGTCATCACCGTCACGCCCAGCGCGACTGCTGTCGGAGCACAAGTTCGGCGCATCGAGATCGAGACCGTCAACGGCACTACCAATTTGCGGGTCGATGAGGCCGGCAAGCCACTAGCAGTGGCGTTACCCTACGGTGAAACCCCATGGGTGAGGATCACCGCGGCTGCCACCGACGATGGGTCCTCCGGGGTGCAGTTCGGCATCACCGACCTAACGATTACCCAGTATGACGCGTCCGGATTCGCCCACCCGGTCAATCTACGGCACACCGCGCTGGTTCCCGGATCACCGCCAGGTTGGGCAGTTGCGGGGTGGGACCTGGGATCGGAATTACTCGGCAGACCGGGCTGCGCTCCGGCGCCCGACAACGTTCGCTGCGCGGCATCGATGACGCTAGCACCAGAAGAACCCGTCAATTTTAGCCGGACATTAACCGTTCCCTACCCGATATCGGTTACAGCAATGCTGTGGGTGCGACCACGACAGGGCCCTAAGCTGGCGGACCTGATCGCCGAGCCGAAGACCACCCGAGCCTACGGTGAAGCCGACACGGTCGACATCCTTGGTTCGGCATATGCGGCCACCGACGGCAATCCGGCCACTTCGTGGACGGCACCGCAACGGGTGGTGCAGCACAAGACCCCTCCGACACTCACCCTCGTCCTTCCGCGGCCCACCGAGGTCAACGGGCTGCGGCTAGCACCCAGCCGGTCGGCACTGCCCGCGCGTCCGACGCTAGTGGCGGTGAACCTGGGCAATGGCCCACAAGTTCGAGAGTTGCAGGCCGGTGAACCACAGGCGCTTTCGCTGAAGCCCCGAATAACCGATACTGTCACGATTAGCCTGCTCGACTGGCACGACGTCATCGACCGCAACGCGCTGGGTTTCGATCAGCTCAAACCACCAGGGCTGGCCGAGGTTACGGTGCTCGGGACCGACGGCAACCCAATCGCACCTGCCAACGCCAGCCGCAACCGCATCCGTGAGGTCACAGTAGACTGCGATCACGGACCAATCATCGCGGTCGCAGGCCGATTTGTGCACACTTCGATCCGGACCACGGCAGCAGCACTGCTGGATGGCGAACCGGTCGCCGCGGTCCCCTGCGAACGCGCCCCTATAGTACTGCCGGCAGGCCAGCAAGAGTTGTTGATCAGCCCTGGTGCCGCGTTCATCGTGGATGGGGCGCAGTTATCGACTCAGGACGGAACAGAATTGCCCAGTGCCAGAACAATTTCCGCCGATACCGGCAAGTGGGGTCCCAGTCGGCGCGAGGTGCGCGCCCCCGGGTCGGCCACCTCCCAGGTATTGGTTATGCCCGACAGCATCAACCCTGGCTGGGTGGCTCACACCAGTACCGGAGTCCGCTTGATGCCAGTTGCCGTTAACGGATGGCAGCAAGGTTGGCTAGTGCCGGCGGGGAACCCCGGCACCATCACGCTGACCTTCACCGCTAACTCGCTGTACCGACCTGGCCTGGCGGCGGGGCTGGCATTGCTACCGCTACTGGCCTTGCTTGCCTTATGGGGCAGGCGAAATGAACGGGCTGCTGACGCGGCAGCGCAACCATGGACACCTGGAGCCTGGTCCGCGGTCGCAGTGTTGTCGGCAGGAGCGGTTATCGCCGGCGCAGCCGGGGTTGTTGTGGTCGGTGCCGCTCTCAGTTTGCGGTATGCGTTGCGCCATCAGCAGCGGTGGCGCAACGGCCTTACCGTCGGTTTGAGCGCAGGTGGGCTGGTTTTAGCCGGCGCAGCGCTGTCCCGACAGCCGTGGCGATCGGTCGACGGATACTCCGGACATTCCGCGAATGTTCAACTACTAGCATTAATTTCGCTCGCCGCATTGGCCGCATCAGTGGTGTCGCCGCGGTGTGGCAGCACGGGGGTAGCTACTTGACGAGCGAT

Protein Sequence 

>ML2570_ML2570_protein
NVALVVGVGRGRRGGVDVRAIPGTDLPRYQTGPNHQPATLSGPRDQPVE_RPAVWSGAESGLRLSVSARHLLSHRTATGITRMDNPAFVVGAAADGRVLGTTPSRRDTEHRQSNFTRDWRGSVCVIATGADHTGVDLVGNSADDAVAVGVAAHDSSFAGSSGQVGADTCRAGGAGGRVDGCS_RHCNAGRLSACSDLVGLSPTEPLVVALYRVVAVSTVFGNAVVGGGTGSAARRQSPVLGLHRILRRYHAMVVVS_DAARHRQLDTLRGTDRYRGHTTGHRVGGHPGHLPGSGGRIGRAG_HWDAGSRSAGNDVGNRSGIAIRRLQRWVGLAAGAGGAGVPGLQRRSTAQRAQTGVGDPNPVRIGHRRASGPNPPTGQRAGIGVAELVCPPRARQTSRRDSGGVNRTVGQHLVSVDGSAHPARHVQCDTAILARHQ_LAQRTQHGNTDTWTGAGGTGRAVRHSGVGHQPRRAAAGARQ_PMGSARLHPADSAAGYPGAGFGATAIRLRTPVGWPGRYPCPPRHFLRGAAQRSGSRHVALSSPDPGTPGHRRVTAAGKSSAVRCTSGHQHAQRFRCRQRIASLVPSGGDLSGGR__WDQSRQTLLRRHRPTSPHRRRTRSAAAS_RTAPTTGTACIRSGADDRRRPVRWSATTQPGRGHHNRYPGSTRDRLRPSRPALVGDPRS_RRPAYFQPSTRLPSPWRRNGIRGLERWPDHRVKLVIGCHLDARCRSGNLTGRRHRRRPGDLVGVQRTAARRRSMAASRF_PPGKQRRHHRHAQRDCCRSTSSAHRDRDRQRHYQFAGR_GRQATSSGVTLR_NPMGEDHRGCHRRWVLRGAVRHHRPNDYPV_RVRIRPPGQSTAHRAGSRITARLGSCGVGPGIGITRQTGLRSGARQRSLRGIDDASTRRTRQF_PDINRSLPDIGYSNAVGATTTGP_AGGPDRRAEDHPSLR_SRHGRHPWFGICGHRRQSGHFVDGTATGGAAQDPSDTHPRPSAAHRGQRAAASTQPVGTARASDASGGEPGQWPTSSRVAGR_TTGAFAEAPNNRYCHD_PARLARRHRPQRAGFRSAQTTRAGRGYGARDRRQPNRTCQRQPQPHP_GHSRLRSRTNHRGRRPICAHFDPDHGSSTAGWRTGRRGPLRTRPYSTAGRPARVVDQPWCRVHRGWGAVIDSGRNRIAQCQNNFRRYRQVGSQSARGARPRVGHLPGIGYARQHQPWLGGSHQYRSPLDASCR_RMAARLASAGGEPRHHHADLHR_LAVPTWPGGGAGIATATGLACLMGQAK_TGC_RGSATMDTWSLVRGRSVVGRSGYRRRSRGCCGRCRSQFAVCVAPSAAVAQRPYRRFERRWAGFSRRSAVPTAVAIGRRILRTFRECSTTSINFARRIGRISGVAAVWQHGGSYLTSD

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML2570 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

5 proteins show strong predicted evidence for PPIs

11 show intermediate predicted evidence for PPIs

121 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML2570

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.