gabD
mL2573
PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE [NADP+] DEPENDENT (SSDH) GABD
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3072692 – 3074065
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2573_gabD_dna
CGCCACCATCAACCCGGCCACCGGCGAGACGGTCAAGACCTTTACACCGACAACCCAGGATGAAGTCGAGGATGCGATTGCTCGCGCCTATGCGCGGTTTGACAACTACCGTCACACTACCTTCACTCAACGGGCCAAGTGGGCTAACGCCACCGCCGACCTGCTCGAAGCTGAAGCCAACCAATCCGCCGCCCTGATGACCCTCGAAATGGGTAAGACGCTGCAGTCAGCTAAGGATGAGGCAATGAAGTGCGCCAAGGGTTTTCGCTACTACGCTGAGAAAGCCGAAACGTTGCTCGCAGATGAGCCGGCCGAAGCCGCCGCCGTTGGTGCGTCGAAAGCATTAGCCCGTTACCAGCCGCTCGGTGTGGTACTGGCTGTTATGCCGTGGAACTTTCCGCTGTGGCAGACTGTTCGGTTCGCTGCACCGGCGCTGATGGCAGGCAACGTCGGCCTCCTAAAGCACGCGTCAAACGTGCCGCAGTGCGCGTTGTACCTCGCCGACGTCATTGCCCGTGGCGGCTTTCCGGAGGACTGTTTCCAAACGCTGCTCATCTCGGCCAATGGTGTCGAAGCCATTCTGCGTGATCCCCGGGTCGCGGCGGCCACCCTCACCGGTAGCGAACCAGCCGGCCAGGCGGTCGGCGCCATTGCGGGCAACGAGATAAAGCCCACTGTGCTAGAGCTTGGCGGCAGCGACCCTTTCATCGTGATGCCCTCGGCGGATTTGGATGCGGCAGTTGCCACCGCGGTTACCGGACGGGTGCAGAACAACGGCCAATCCTGCATCGCCGCCAAGCGGTTTATCGCCCATGCCGACATTTACGATGAGTTCGTCGAAAAATTCGTCGCCAGGATGGAAACGCTGCGAGTGGGTGACCCTACCGACCCGGACACCGACGTCGGTCCGCTGGCCACTGAGTCGGGCCGCGCCCAAGTCGAACAACAAGTCGACGCCGCAGCAGCAGCAGGCGCAGTGATCCGTTGCGGCGGTAAACGTCCCGACCGGCCGGGGTGGTTCTACCCACCGACCGTGATTACCGACATCACCAAGGACATGGCACTCTACACCGACGAGGTCTTTGGTCCGGTCGCCTCAGTATACTGTGCCACAAACATCGACGACGCCATCGAAATCGCCAACGCTACCCCCTTTGGGTTGGGTTCCAACGCTTGGACGCAGAACGAGTCCGAGCAACGACACTTCATCGACAACATCGTCGCCGGGCAGGTCTTCATCAACGGTATGACGGTATCCTATCCCGAATTGCCGTTCGGCGGTATCAAACGGTCAGGCTACGGCCGAGAGCTGTCGACCCATGGGATCCGTGAGTTCTGCAACATCAAGACAGTTTGGATCGCATAGAACAGCCT

Protein Sequence 

>ML2573_GabD_protein
RHHQPGHRRDGQDLYTDNPG_SRGCDCSRLCAV_QLPSHYLHSTGQVG_RHRRPARS_SQPIRRPDDPRNG_DAAVS_G_GNEVRQGFSLLR_ESRNVARR_AGRSRRRWCVESISPLPAARCGTGCYAVELSAVADCSVRCTGADGRQRRPPKARVKRAAVRVVPRRRHCPWRLSGGLFPNAAHLGQWCRSHSA_SPGRGGHPHR_RTSRPGGRRHCGQRDKAHCARAWRQRPFHRDALGGFGCGSCHRGYRTGAEQRPILHRRQAVYRPCRHLR_VRRKIRRQDGNAASG_PYRPGHRRRSAGH_VGPRPSRTTSRRRSSSRRSDPLRR_TSRPAGVVLPTDRDYRHHQGHGTLHRRGLWSGRLSILCHKHRRRHRNRQRYPLWVGFQRLDAERVRATTLHRQHRRRAGLHQRYDGILSRIAVRRYQTVRLRPRAVDPWDP_VLQHQDSLDRIEQP

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding GabD with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

16 show weak predicted evidence for PPIs

View all pooled AlphaFold results for GabD

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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