ML2581
mL2581
PROBABLE CONSERVED MEMBRANE PROTEIN
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3081546 – 3082829
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2581_ML2581_dna
AGCAGTCATTTTGCGGTTCACCGCATGCGGGATCATCGGGCTCGGCGCCGCCTTTTTGATCGCCGCATTGCTGCTGGCAACATATACTAGCAGCAGAATCACCAAAATCCCGCTTGATATCGACGCAACATTGGTTAGCGAAGGAAACGGAACCGCGCTCGATTCAAGCTCTTTGTCCAGTGAGCACATCATCGTCAACCAGAATGTGCCGCTAGTGTCCCAACAGCAGATCACTGTTGAGTCGCCGGCCAACGTTGACGTGGTCACGTTTCAGGTCGGTGTCTCGATTCGGCGCACCGATAAGCAAAAGGACACCGGACTACTGCTGGCCGTCGTCGACACCGTCACACTCAATCGTAAAACAGCGATGGCTGTTTCGGACGACACACACACCGGCGGCTCCATCCAGAAGCCGCGCGGATTCACTGACGAGAACCCGCCTACCGCCATCCCGTTGCGGCACGACGGATTGTCCTACCGGTTCCCCTTCCACACCGAGAAAAAGACGTATCCGTACTTCGACCCGGTAGCACAGAAGACGTTTGACGTTAATTACCAAAACCAAGAAGACATCAACGGTTTAACTACTTATCGCTTCACACAGAACGTCGGCTATGATGCCGACGGCAAGCTGGTGGCCCCAATAACCTACCCGTCGCTGTACGCCAGCGATGAGGACGGCAAAATCACCACCACCGCGGCGATATGGGGTTTGTCCGGGGATCCGTCGGAGCAGATCACCATGACCCGCTACTACGCCGCGCAGCGTACGTTCTGGGTGGATCCGGTGTCAGGCACCATCGTCAAGGAAACCGAGCACGTCAACCACTACTTTGCCCGCGATACACTAAAGCCAGAGGTGACGCTGGCCGATTACAAGGTCACTTCCACCGAAGAGACCATCGAATCTCAGGTCAACTCGGCCCGTGACGAACGGGACCGACTGGCGCTATGGTCGCGAGTGTTGCCGATCACGTTCACCGCGGTCGGCTTGATCACACTGCTAAGTGGTGGATTCCTGGCTTCGTTCAGCCTGCGGACCGAGAGCGCGCTGACCGAATCCGGTCTGGACCGGGCAAACCGCGACGCCTTCGGCCACTGCCGCACCGAGGAACCAGTTCCTGGCGCTGAAGCCGAGACCGAGAAACTGCCCACCCAACGCCCTGAACTGCGTGATTCTAGTATACTCAGCGTCAGTGCGCACCGACGACGTTCAAGCGAGTCGTCACCACCCAATTCGGGGCCAGCCGACCCTGGCCACCCTGAACGGGGATAACTCGGCAA

Protein Sequence 

>ML2581_ML2581_protein
SSHFAVHRMRDHRARRRLFDRRIAAGNIY_QQNHQNPA_YRRNIG_RRKRNRARFKLFVQ_AHHRQPECAASVPTADHC_VAGQR_RGHVSGRCLDSAHR_AKGHRTTAGRRRHRHTQS_NSDGCFGRHTHRRLHPEAARIH_REPAYRHPVAARRIVLPVPLPHREKDVSVLRPGSTEDV_R_LPKPRRHQRFNYLSLHTERRL_CRRQAGGPNNLPVAVRQR_GRQNHHHRGDMGFVRGSVGADHHDPLLRRAAYVLGGSGVRHHRQGNRARQPLLCPRYTKARGDAGRLQGHFHRRDHRISGQLGP_RTGPTGAMVASVADHVHRGRLDHTAKWWIPGFVQPADRERADRIRSGPGKPRRLRPLPHRGTSSWR_SRDRETAHPTP_TA_F_YTQRQCAPTTFKRVVTTQFGASRPWPP_TGITRQ

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML2581 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

3 proteins show strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

53 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML2581

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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