mce1A
mL2589
MCE-FAMILY PROTEIN MCE1A
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3092454 – 3093779
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2589_mce1A_dna
ATCAACAAAGATCAACGCGTCACGAAAGCCGCCGTACAAGTTGGCCGGGGTTGGCTTGTTGGTCGTGGCTGTAGTGATTTTCGGCTTGGTCTACGGGCAGTTTCGGGGAAATTTCACCCCTAAGTCCAAGTTGACGATGCTGGCCGATCGGGCTGGGTTGGTGATGGATCGGGGCTCGAAGATAACCTACAACGGGGTTAAAATTGGCCGGGTCGCCGACATCTCGGAGACTGTGCGGAACGGCAGGCCGGTCGCCGAATTCACTTTGGATGTGTATCCGCGGTACCTGTCTCTAATTCCGGCCAATGTGAACGCCGACATCAAGGCGACCACGGTCTTCGGCGGTAAGTATGTGTCCTTGACGACGCCGGAACATCCGTCGCAGAAAAGGCTCACCCCGCAGACCGTGATCGACGCCAGGTCGGTGACCACGGAGATCAACACATTGTTCCAGACCATAACCTTGATCGCGGAGAAAGTGGATCCGATCAAGCTAAACCTGACGCTGAGCGCGGCCGCACAATCACTGGCTGGGCTTGGCGAGAGGTTCGGACAATCAATCGTCAATGGAAATTCGGTTCTTGACGACGTCAACTCGCAGCTGCCGCAGGCTCGTCACGACATCCAACAGCTGGCGTCCCTGGGGGACACTTATGCTAACTCCGCTTCGGATTTTTTTGATTTCCTTAATAATTCGATCGTCACGTCGCGCACGATCAACCAGCAGCAGAAGGACTTGGACCAAGTGTTATTGGCCGCGGTCGGGTTCGGCAACACCGGCGCGGATATCTTCTCCCGCAGTGGGCCGTATCTGGCGCGGGGTGCCGCCGACCTAGTGCCCACGGCCCAGTTGTTGGATACCTACAGCCCGGCGATTTTCTGCACCCTGCGCAATTATCATGACATCGAACCCAAGGTCACATCGTTTCTCGGCGGCAACGGCTACTCTATCAATGATCATGTCGAGCTGCTGTCGGGGTTGGGATTCCTGCTGAACCCGACATCAGCGATATCCATCATCGGGGCAGGAGTCCTCTCACAAGGACTCCTAGCTCCACTCGGGCTAGCCGGAGTGGTCAACGGGGCAGCCAATCCCTACATCTATCCGGAAAATCTGCCGCGGGTCAACGCTCGGGGTGGGCCGGGGGGGGCGCCGGGTTGTTGGCAGCACATCACCCGTGATCTCTGGCCCACGCCCGAGTTAGTCATGGACACCGGCAACAGCATTGCGCCATACAACCACTTGGATAGCGGTTCGCCATACGCCATCGAGTACGTCTGGGGCCGTCAAGTAGGGGATAACACAATCAACCCATGAAACTCACC

Protein Sequence 

>ML2589_Mce1A_protein
INKDQRVTKAAVQVGRGWLVGRGCSDFRLGLRAVSGKFHP_VQVDDAGRSGWVGDGSGLEDNLQRG_NWPGRRHLGDCAERQAGRRIHFGCVSAVPVSNSGQCERRHQGDHGLRR_VCVLDDAGTSVAEKAHPADRDRRQVGDHGDQHIVPDHNLDRGESGSDQAKPDAERGRTITGWAWREVRTINRQWKFGS_RRQLAAAAGSSRHPTAGVPGGHLC_LRFGFF_FP__FDRHVAHDQPAAEGLGPSVIGRGRVRQHRRGYLLPQWAVSGAGCRRPSAHGPVVGYLQPGDFLHPAQLS_HRTQGHIVSRRQRLLYQ_SCRAAVGVGIPAEPDISDIHHRGRSPLTRTPSSTRASRSGQRGSQSLHLSGKSAAGQRSGWAGGGAGLLAAHHP_SLAHARVSHGHRQQHCAIQPLG_RFAIRHRVRLGPSSRG_HNQPMKLT

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Mce1A with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

4 show intermediate predicted evidence for PPIs

40 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Mce1A

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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