mce1C
mL2591
MCE-FAMILY PROTEIN MCE1C
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3094813 – 3096372
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2591_mce1C_dna
GCTGGAACTCCCCAATCGACTTCGCAGTGGGCTCATCGGAGTCCTGGTGGTCCTTCTCATCATCGGTGTGGGCCAAAGCTTCACCAGTGTCCCGATCTTGTTCGCCCGACCCAGCTACTACGGGCAGTTCACCGACACCGGTGGACTCAACAAGGGCGACAAGGTGCGCATTGCCGGCATGGATGTTGGCAAGGTGGAGGCGCTGAAGATCGACGGTGACCACGTCGTGATCAAGTTCTCCATCGGCACTAACCGCATCGGCACTGCGAGTCGGCTGGGGATCCGCACCGACACCGTACTCGGCAAGAAGGTCCTCGAGGTCGAGACGCGCGGCACCCAGCTGTTACGGCCCGGGGACAGTTTGCCGTTGGGCCAAAGCACGACTCCCTACCAGAGCTATGATGCGTTCTTCGACGCCACCAAGGTCGCTTCGGGCTGGAACATTGACACCATCAAGCAGTCGCTGAAGGTGGTGTCGGAAACCATTGATCAAACATACCCGCATCTAAGCGCTGCACTCGATGGTGTGGCCAAGTTCTCCGACACCATCGGCGCACGCGACAAGGAGATCAAACACCTGATTGCGCAGGCCAACCAAGTGGCTAGTGTCCTCGGTGACCGTGGCGCACAAGTGGACCGATTGTTGGTCAACACCAAGACTTTGATCGCGGCGTTCAACGAACGCGGACGTGCCGTCGATGCATTGCTGGGTAACGTCGCTGCGTTTGCTGCCCAGGTGCAAAGATTGATCAACGACAACCCGAACCTCAATCACGTGCTGGAACAGTTGCACCAGCTGAGTGGCATCTTGGTTCAGCACAAAGACGACCTGGCTAATACTCTCATTCAGGTCGCCGCATTCTTACCATCGTTGAATGAGGCCATCGGGTCGGGACCCTTCTTCAAGGTGGTCTTGCACAACTTGGCGCCGTATCAGATTTTGCAGCCGTGGGTCGACGCCGCGTTTAAGAAGCGCGGTATCGACCCAGAGAACTTCTGGCGCAGCGCCGGGTTGCCGGAATTCCGGTTTCCCGACCCCAACGGCACCCGCTTCCCGAATGGCGCACCGCCGCCTGCGCCACCGGTGCTAGAGGGCACCCCGGAAAATCCGGGACCGGCTGTTCCACCGGGATCGCCATGCTCCTACACTCCGGCGCATCCGGGCGGCAATAACACCATCGGGGATGAAATGGGTCTGCCCCGGCCGTGGAATCCGCTCCCATGCGCTGGTGCGACAGCAGGACCGTACGGTGGACCCGCCTTCCCGGCGCCGATAGACGTCCAAACGTCGCCACCGAACCCCGATGGGCTGCCACTGCTGCCAGGCATCGCGATTGCTGGGCGGCCGGGTGATCCAGCTCCGAACGTCCCAGGTACTCCGGTGCCCCTACCGCCGAACGCGCCGCCAGGTGCGCGCACCGAGCAGCTGGCACCTGCCGCCCCGGCGCAGGATTCATCGGCACCGCATGAGCCCAGGGAACAGCTGTCAGCACCGTTGATTAACCCGGGAGGCACAGGAGGTAGCGGCGGCGCAGGAGGTAGTCGGAATTGAGTACCATC

Protein Sequence 

>ML2591_Mce1C_protein
AGTPQSTSQWAHRSPGGPSHHRCGPKLHQCPDLVRPTQLLRAVHRHRWTQQGRQGAHCRHGCWQGGGAEDRR_PRRDQVLHRH_PHRHCESAGDPHRHRTRQEGPRGRDARHPAVTARGQFAVGPKHDSLPEL_CVLRRHQGRFGLEH_HHQAVAEGGVGNH_SNIPASKRCTRWCGQVLRHHRRTRQGDQTPDCAGQPSG_CPR_PWRTSGPIVGQHQDFDRGVQRTRTCRRCIAG_RRCVCCPGAKIDQRQPEPQSRAGTVAPAEWHLGSAQRRPG_YSHSGRRILTIVE_GHRVGTLLQGGLAQLGAVSDFAAVGRRRV_EARYRPRELLAQRRVAGIPVSRPQRHPLPEWRTAACATGARGHPGKSGTGCSTGIAMLLHSGASGRQ_HHRG_NGSAPAVESAPMRWCDSRTVRWTRLPGADRRPNVATEPRWAATAARHRDCWAAG_SSSERPRYSGAPTAERAARCAHRAAGTCRPGAGFIGTA_AQGTAVSTVD_PGRHRR_RRRRR_SELSTI

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Mce1C with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

58 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Mce1C

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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