lprK
mL2593
POSSIBLE MCE-FAMILY LIPOPROTEIN LPRK (MCE-FAMILY LIPOPROTEIN MCE1E)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3097961 – 3099139
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2593_lprK_dna
TGCAATGAGTGTGGTACACACTAGCCGGGTGCGTCACCAGACCTGGCGGGGGCTGGTGATGTTGGTGGCCGCGCTGTTGCTGAGCTCCTGTGGTTGGCGTGGAATTTCTAACGTCTCGATTCCGGGTGGTCCGGGCAGCGGCAAGGGAGCTTACACCATCTATGTGCAGGTGCCGGACACGCTGGCGATTAACGGCAACAGCAAGGTGATGGTTGCCGACGTCACAGTTGGCTCGATACGCGCCATCAACTTGAAGAACTGGGTGGCCACCCTGACTCTGGGTTTAAACAAGGACGTCCAGCTACCGAAGAACACCACCGCCAAGATCGGACAGACCAGTTTGTTGGGCTCTCAGCATGTGGAGTTGGCCGCGCCGGCAAACCCGTCACTGGAATTACTCAAGAATGGTGACACCATCCCGCTGAAAAATTCGTCGGTGTTCCCCACCACCGAGCAAACATTAGCCAGTCTCTCCTTGATCTTGCGCGGAGGTGGTATTCCGAACCTGGAAACGCTAACAAACGAGGTTTTCAATATATTCCACGGGCGAGCCGACCAGATCCATGCCTTCTTAACAAAGCTAGATACCTTTGCTAGTCAGCTCAACCAGCAACGCGATGACATCACCCACGCTATCGACTCGACCAACCGACTGCTGACCTATGTGGGTGGCCGCTCGGATGTCCTCGATCAAATACTGACCGACATCCCGCCGTTGATCAAGCATTTCGCCGACACCAAAAACTTGCTCATAAACGCTGTTGGTTCGGTTGGACAGCTCAGCCAGGCCGTCGATCAGTACTTGTCGGAGGCACGTGGTCCTCTGCACACCGACTTGCAAGCGTTGGCATGTCCACTGCGAGAACTCGGCCGTGGCGCGCCGTATTTCATCGGCGCGATGAAGTTGATCCTGACCCAGCCGTACGACGTCGACACGGTTCCGAAGATAATGAGGGGCGACTACCAAAATGTGTCGCTGACATTAGACGTCACTTACAGCGCCATGGACAATGCGGTTCTTACCGGTACCGGATTGTCTGGGGCTCTCCGTGCCCTCGAGCAATCCTTTGGTCGCGATCCTGAAACGATGATCCCCGACGTTCGCTACACGACGAACCCCAATGACGCACCCGGCGGACCGTTGGTGGAAAGGGCCGATAGGCGATGCTGACTCCCCTC

Protein Sequence 

>ML2593_LprK_protein
CNECGTH_PGASPDLAGAGDVGGRAVAELLWLAWNF_RLDSGWSGQRQGSLHHLCAGAGHAGD_RQQQGDGCRRHSWLDTRHQLEELGGHPDSGFKQGRPATEEHHRQDRTDQFVGLSACGVGRAGKPVTGITQEW_HHPAEKFVGVPHHRANISQSLLDLARRWYSEPGNANKRGFQYIPRASRPDPCLLNKARYLC_SAQPATR_HHPRYRLDQPTADLCGWPLGCPRSNTDRHPAVDQAFRRHQKLAHKRCWFGWTAQPGRRSVLVGGTWSSAHRLASVGMSTARTRPWRAVFHRRDEVDPDPAVRRRHGSEDNEGRLPKCVADIRRHLQRHGQCGSYRYRIVWGSPCPRAILWSRS_NDDPRRSLHDEPQ_RTRRTVGGKGR_AMLTPL

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding LprK with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

3 show intermediate predicted evidence for PPIs

33 show weak predicted evidence for PPIs

View all pooled AlphaFold results for LprK

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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