mmpL11
mL2617c
PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL11
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3122785 – 3125826
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2617c_mmpL11_dna
CAGTTGATGATGCGCCTGAGCAGCTACCTGCGTCGGTTCCGCTGGTTGGTCTTCACAGGCTGGTTACTCGCTCTGGTCCCGGCAATCTACTTGGCGATGACGCAGTCGGGGAAGCTCACCGGTGGTGGGTTCGAAGTTGCCGGGTCACAGTCGCTGCTGGTCCACGATCAGCTGCAAGAGCAATATCCCGACCAGGGAGCTGTTTCGTTGGCCTTGGTGGCTGCTCCCCGCTCGGATGCCAGCTACCAGGACATGAACGACGCTGTCGCACTGCTAAGACGGATTGTCAGCGAGTTCCCTGGCGTGTCGGAAGTGCCCAACCCCACCCAGCTGCCGCCGCGACCCGATCGGCCGTATGGTGTGTCACTGCGTTTGGATGATCGCAACTCGGTCACTAGCGATGTCGCCAAGCAACTACGCACCAAGGTAGGTATCAAGGGCGACCAAGCGGGGCGGACCGCCAACGGCAAAGTGCGACTCTATGTTATCGGGCAGGGAGCACTCAGTGCCGCTGTGGCGGCCAACAGCAAGCACGACATCGCCGAAGCGGAACGATGGAACCTGCCGATCATTCTGATCGTCCTGCTCGCGGTATTTGGTTCGCTGGCCGCCGCGGCAGTTCCGCTAGCCTTGGGCGTTTGCACCGTCGTGGTCACCATGGGCTTGGTCGACCTAGTGTCGATGCACACCATCATGTCGGTGTTCGTGACTTCGACGGTGTCGATGTTTGGCATCGCTCTGGCCGTTGACTACTCCTTATTCATCCTGATGCGTTTTCGCGAGGAGCTGCGGTCCGGTCGGCAACCACAGGAAGCTGTCGACGCCGCGATGGCTACTTCCGGGCTCGCGGTGGTGCTGTCCGGTATGACCGTCATCGCCTCGCTCACCGGAATCTATTTGATCAACACTGCGGCGCTGAAGTCGATGGCGACCGGAGCGATTCTGGCCGTTGCTATCGCTATGCTGGCATCGATTACCTTGACACCCGCGGCTTTAGCCACGTTCGGCCGGGCTGCTGTCAAAAGGTCAGTGCTGATGCACTGGTCGCAGCGGTCGGAGTGCACCCAGTCCCTGTTCTGGACCCGCTGGGTGGGGTGGGTGATGCACCGGCCGTGGATTTCGGCGTCGGCGGCGTCGACCATCCTGATTATCATGGCGACGCCGGTGACATCGATGATGTTGGGCAACAGCCTGCTGCGGCAGTTCAACTCTTCGCACGAGATCCGTGCGGGAGTGGCGGCCGCGGCCCAAGCGCTCGGTCCAGGCGCACTGGGGCCCGTTCAGGTACTGATCACCTTTCCTGACGACCCGAACACTCAAGCATCATCACCCAAACACCGCCAGACAATCGGGGCTATCCGCAACAGGATGCTACAGGCTAAGAACGTCATGTCGGTAGCACCACCGCAATTCGCCGACAATAATTGCAGCGCGTTGCTAGGTGCGGTGTTGTCGGTCGATCCCGAGGACCTGGGCGCCCGAGAAACCGTCGATTGGATGCGTACGGAGCTTCCTAAGGTTCCCGGCGCGGCCCACGTAAATGTCGGCGGACCGACCGCGCTGATCAACGACTTTGATGACCGGGTGGCCAAGACGGAGCCGCTGATGCTGGTCTTCGTCGCACTGATCGCGTTCGTGATGCTGTTGATCTCGATCCGCTCGGTGTTCCTAGCATTCAAAGGCGTGCTGATGACATTGTTGTCGGTGGCCGCCGCCTATGGCAGCTTGGTGATGGTGTTCCAGTGGGGCTGGCTGGAGAACCTCGGTTTCACACACATCAATTCGATCGACAGCACGGTTCCCCCACTGGTGCTGGCGATGACCTTCGGGTTGTCGATGGACTACGAAATCTTCCTGCTCACACGCATCCGGGAACGTTTCCTGCAAACCGGGCATACTCGCGACGCGGTCGCCTACGGGGTGAGCACCAGCGCACGCACTATTACCAGCGCTGCCCTGATCATGATCGCGGTGTTCGTCGGCTTCGCGTTCGCCGGCATGCCGCTAGTGGCAGAGATCGGCGTGGCGTGCGCCGTCGCGATCGCGGTTGACGTGACTGCGGTGAGACTGGTTCTGGTACCGACGCTGATGGCGATGTTCGCGCAATGGAACTGGTGGCTACCCCGCTGGTTGTCCCGGGCCTTACCCGCCGTCGACTTCGACAAGCCATTCCCGCCGGTCGATCTCAATGAGATCGTAGTTCTCCCCGCTGACATCTCAGCAACCAAAGTGCCCTGTGGCGACCTGCGGATGGTGCTCAAGTTGGCGGCGAAGCTCAAGAACCTGGCGCCGGACGCAATCTGCGTGGCCGACCCACTCGCCTTCACCGGGTGTGGGCGCAACAACAAACGATCCGACCGGGTTCTGCCAGGCGCTGCTACGCAAGAATCAGAAGAGGACCCCGCAATGGGTAAAGCCAGCGATAGCACCGCGGCACTTACTGCAGCTCAGGTAGGCCCGGTGACCAGAACCAACGGTCACTGGACGGCCAGGAATCTTGTCATCGGCTTGACGCACCGCAACAGCATTACGCGAGTAATGCCCTGGTCTGACCGGCCGGTTCATCCGTTCACTTTGTGGCGTAGCCGGTTCTCAGTCGCCATCGACGCGCTGGAGGCGCATATAGCCGTGCAAGCCGACGCCCCCGATCAACCAAATTACCAGCGGTGCAGCCCGGTGGAGACCGCTCACGTCCAACTACCCACCGGCGATCGGTTGCTGATCCCCACAGGCGCAGAAACGCTACGCCTGGTGAGCTATCTGATCATGTGTCGTAACAGCATCCGCGACTACGCCGAATTGGCTGACATGGTCGATGCGATAGAGCCCGAGACTGCGGCCGTAGTGCTAACCGAGCTAGATAGATATTACTCTTGTCAACTACCCATGCGGCAATGGATGGCAACCCAGTTGGTCCGTCGGCTCTCGGACCCCCATCCCGTTGACCTCACTGAAGATCAGTGGTCTGATCCGGATAACAAGGCAGAATGGCAGGACGTCAGGCAGCGTTGTCTGTCAGTGGCTGTAGCGATGCTCGAGGAG

Protein Sequence 

>ML2617c_MmpL11_protein
QLMMRLSSYLRRFRWLVFTGWLLALVPAIYLAMTQSGKLTGGGFEVAGSQSLLVHDQLQEQYPDQGAVSLALVAAPRSDASYQDMNDAVALLRRIVSEFPGVSEVPNPTQLPPRPDRPYGVSLRLDDRNSVTSDVAKQLRTKVGIKGDQAGRTANGKVRLYVIGQGALSAAVAANSKHDIAEAERWNLPIILIVLLAVFGSLAAAAVPLALGVCTVVVTMGLVDLVSMHTIMSVFVTSTVSMFGIALAVDYSLFILMRFREELRSGRQPQEAVDAAMATSGLAVVLSGMTVIASLTGIYLINTAALKSMATGAILAVAIAMLASITLTPAALATFGRAAVKRSVLMHWSQRSECTQSLFWTRWVGWVMHRPWISASAASTILIIMATPVTSMMLGNSLLRQFNSSHEIRAGVAAAAQALGPGALGPVQVLITFPDDPNTQASSPKHRQTIGAIRNRMLQAKNVMSVAPPQFADNNCSALLGAVLSVDPEDLGARETVDWMRTELPKVPGAAHVNVGGPTALINDFDDRVAKTEPLMLVFVALIAFVMLLISIRSVFLAFKGVLMTLLSVAAAYGSLVMVFQWGWLENLGFTHINSIDSTVPPLVLAMTFGLSMDYEIFLLTRIRERFLQTGHTRDAVAYGVSTSARTITSAALIMIAVFVGFAFAGMPLVAEIGVACAVAIAVDVTAVRLVLVPTLMAMFAQWNWWLPRWLSRALPAVDFDKPFPPVDLNEIVVLPADISATKVPCGDLRMVLKLAAKLKNLAPDAICVADPLAFTGCGRNNKRSDRVLPGAATQESEEDPAMGKASDSTAALTAAQVGPVTRTNGHWTARNLVIGLTHRNSITRVMPWSDRPVHPFTLWRSRFSVAIDALEAHIAVQADAPDQPNYQRCSPVETAHVQLPTGDRLLIPTGAETLRLVSYLIMCRNSIRDYAELADMVDAIEPETAAVVLTELDRYYSCQLPMRQWMATQLVRRLSDPHPVDLTEDQWSDPDNKAEWQDVRQRCLSVAVAMLEE

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding MmpL11 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

10 show intermediate predicted evidence for PPIs

100 show weak predicted evidence for PPIs

View all pooled AlphaFold results for MmpL11

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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