mmpL3
mL2620c
POSSIBLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL3
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3128842 – 3131709
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2620c_mmpL3_dna
GGAGCTTACGTGTTCGCCTGGTGGGGTCGAACTGTGTACCGCTACCGATTCATCGTAATCGGGATCACGGTCGCTCTGTGCCTGTGCGGCGGAGTTTTCGGGCTGAGCCTAGGTAAGCACGTCACGCAGAGTGGTTTCTACGACGACAGTAGTCAGTCGGTGAAAGCCTCAATCCTTGGTGACCAGGTCTATGGCCGGGACCGAAGCGGCCACATCGTGGCGATCTTCCATGCGCCCGACGGCAAAACCGTCAATGACCCGGCATGGGCGAAGAAGATCACCGATGAACTTAACCAGTTCCAGCGAAACAACTCCAATAAGGTGACGGGATGGGCCGGCTACTTGCGCGCATCCGATACGACCAACACGGTTGTTCAGGGCATGGCCACCCCGGACAAAAAGTACACGTTTGTGTCCATACCCCTTAAGGGGGACGACGACGACACCATCCTCAACAACTACAAAGCCATAGCTCCGGACCTGCAAAAACTGGACGGTGGTACCGTCCAGCTCGCTGGCCTCGACCCAATCGCCAACGCCTTGACCAGCACCATCGCCACCGACCAACGGCGGATGGAAGTCCTGGCGCTGCCGCTGGTGGCAGTGGTGTTGTTTTTGGTGTTCGGCGGCGTAATTGCAGCCTGCTTGCCAGTTATGGTGGGTGGCCTGAGCATCGCGGGTGCACTAGGCATCCTGCGCTTCATCGCACTCTTCGGACCAGTGCACTTTTTTGCCCAACCGGTGGTTTCGCTGATTGGCTTGGGCATCGCGGTGGACTACGGTCTCTTCGTGGTGAGCCGGTTTCGCGAGGAGATAGCAGAAGGCTACGATACCGAAGCTGCGGTGCGACGCACAGTGATGACGGCAGGGCGCACGGTGACATTCTCAGCGGTGCTTATTGCCGCATCGGGAGCTAGCCTGCTACTGCTACCGCAGGGCTTTGTCAAGTCGCTGACCTATGCTCTTATCGCAGCGGTGACACTTGCGGCTTTATTGTCGATCACGCTGCTGCCTGCATGCTTGGCAATCTTGGCCAAACATGTTGACGCACTCGGCGTGCGGACCCTGTTCCGGGTGCCTCTCCTACGCAACTGGAGGATGTCGCACGCCTGTCTCAACTGGCTCGCGGACCGCCTGCAAAAGACCAAGACCCGCGAAGAAGTCGAAGCTGGCTTCTGGGGCAAGCTCGTCAACTTCGTGATGAAGCGGCCCCTAGTTTTCGCCATACCGATCGTTATCGGTATGATCCTGCTAGTTATACCGCTGGGCAACCTCTCATTCGGCGGCATGAGTGAAAAATACCTGCCACCCAACAACGCGGTGCGGCAGTCACAGGAACATTTCGACCAGCTCTTCCCGGGGTATCGCACCAATCCGCTAACGCTGGTTATCCAGACCAGCAACCATCAGCCCGTCACGGACCAGGAAATCGCTGACATTCGTAGCAAAGCGATGGCGATCAGCGGGTTCATCGAGCCGGACAACAATTACGTGAACATGTGGCAAGAGCGCACCGTGGCGCCGGGCGCATCGAAGGATCCGTCGGTCAGGGTCCTGCAGAATGGCTTGATCAATCCGAATGACGCGTCGAAGAAGATCAACGAGCTACGCAGCATCACGCCACCAAAAGGCCTCACGGTATCGGTCGGTGGCACCCCGGCACTCGAGCAGGATTCGATTCACAGCCTGGTTGCACAGGCCCCGCTGATGGTCATTATGCTGATTACCACCACAATGCTATTGATGTTCTTAGCGTTCGGGTCGTTCGTCTTGCCGATCAAAGCCGCGGTGATGAGCGCACTCACACTTGGGTCCACGATGGGCATCCTGACGTGGATCTTCGTCGACGGGCACTTATCCAAATGGCTGAACTTCACGCCGACACCGTTGATGGTGGTGATCATCGCTCTCGTCGTTGCGGTCGGCTATGGCTTGGCAACCGACTACGAGGTGTTCCTAGTATCCCGAATGGTGGAGGCGCGCGCAGAAAGCATGTCGACCCAGGAGGCCGTCCGGATCGGCACCGCGTCCACCGGCCGGCTCATCACCGCGGCAGCGCTGGTCCTTGCCGTGGTCGCCGGTTCGTTCGTATTCTCTGACCTGGTAATGATGAAGTACCTGGCCTTCGGGCTGATGGCAGCGCTGTTGCTGGACGCGACCGTAGTGCGTATGTTCTTAGTGCCGTCGGTAATGAAACTGCTTGGTGACGACTGTTGGTGGGCTCCTCGCTGGGCTCGGCTCCTGCAGAACCGCATAGGGCTGGGCGAAATTCACCTGCCTGACGAGCGCAGGCGGCCGACTGTCAGCGGGCGTCCCGTTCGGCCTCCGGTCACAGCGGCTAGCCTAGCCGCTCCAGCGTCGCGAGTACCGCGTGGCCCTACTCACCCCGCCACGCTGGAGCCGTCGCAGCGGGCACGTTCAGGCCTGGCGAGCCGGCCGCAGATCAAACGGCCTCAGGAACTGCCTTCTGGCGCAAGCACCGCGCGGATACAGATGAGGCCGAGCCAGTCGGTGGAAGCGACAACGACCCGTCTGTCGGTACCTGGCAACGCCCCGACCACTGCAGCGGTGTCCAGCAGCCAAGGCGTGCAAGCCGTACCGCTCGCTGCAACGCGACATCCGTTACCAACCCCGTCACCGGCCTCCGGTCAGACGCGGGCCATGCCGGTTCCGGCGAACCGCTCCAGCGACAATGCGAGCGAGACAGCCGAACCCACAACAGCTCTGCCGATCATGCGGCCACAGGACAACGATTCCGAAGTTGCCACCGAGAAGTTAAACGCCCTAGGACAAGGCGATAATTCGCGCCAGCACCGCCGCGCCACCGGTGGTGGTATTAGTGCGCAGGATCTGCTGCGCCGCGAGGGA

Protein Sequence 

>ML2620c_MmpL3_protein
GAYVFAWWGRTVYRYRFIVIGITVALCLCGGVFGLSLGKHVTQSGFYDDSSQSVKASILGDQVYGRDRSGHIVAIFHAPDGKTVNDPAWAKKITDELNQFQRNNSNKVTGWAGYLRASDTTNTVVQGMATPDKKYTFVSIPLKGDDDDTILNNYKAIAPDLQKLDGGTVQLAGLDPIANALTSTIATDQRRMEVLALPLVAVVLFLVFGGVIAACLPVMVGGLSIAGALGILRFIALFGPVHFFAQPVVSLIGLGIAVDYGLFVVSRFREEIAEGYDTEAAVRRTVMTAGRTVTFSAVLIAASGASLLLLPQGFVKSLTYALIAAVTLAALLSITLLPACLAILAKHVDALGVRTLFRVPLLRNWRMSHACLNWLADRLQKTKTREEVEAGFWGKLVNFVMKRPLVFAIPIVIGMILLVIPLGNLSFGGMSEKYLPPNNAVRQSQEHFDQLFPGYRTNPLTLVIQTSNHQPVTDQEIADIRSKAMAISGFIEPDNNYVNMWQERTVAPGASKDPSVRVLQNGLINPNDASKKINELRSITPPKGLTVSVGGTPALEQDSIHSLVAQAPLMVIMLITTTMLLMFLAFGSFVLPIKAAVMSALTLGSTMGILTWIFVDGHLSKWLNFTPTPLMVVIIALVVAVGYGLATDYEVFLVSRMVEARAESMSTQEAVRIGTASTGRLITAAALVLAVVAGSFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVPSVMKLLGDDCWWAPRWARLLQNRIGLGEIHLPDERRRPTVSGRPVRPPVTAASLAAPASRVPRGPTHPATLEPSQRARSGLASRPQIKRPQELPSGASTARIQMRPSQSVEATTTRLSVPGNAPTTAAVSSSQGVQAVPLAATRHPLPTPSPASGQTRAMPVPANRSSDNASETAEPTTALPIMRPQDNDSEVATEKLNALGQGDNSRQHRRATGGGISAQDLLRREG

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding MmpL3 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

8 show intermediate predicted evidence for PPIs

84 show weak predicted evidence for PPIs

View all pooled AlphaFold results for MmpL3

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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