pntB
mL2634c
PROBABLE NAD(P) TRANSHYDROGENASE (SUBUNIT BETA) PNTB [INTEGRAL MEMBRANE PROTEIN] (PYRIDINE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT BETA) (NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT BETA)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3151473 – 3152891
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2634c_pntB_dna
GGTGGCCAAATGAACTACTTCGTGATCGGCCTCTACATTCTTGCGTTCGCATTGTTCATCACCGGCTTGATGGGCCTGACCGGGCCCAGGACCGCGGTGTCCGGCAACTTGATCGCTGCGGTCGGTATGACCATTGCCGTGGCGGCGACGCTGGTCAAGATTCGGCACACCGAGCAGTGGGTATTGATCATTGCCGCCCTGGTGGTGGGCATCGTCCTTGGCTTCCCTCCGGCACGGCTGACTAAGGTGACTGCGATGCCCCAGCTGGTGGCGTTCTTCAACGGCGTTGGCGGTGGAACGGTCGCGCTTATTGCACTGTCGGAGTTCATCGAGACTAGCGGCTTTTCGGAATTTCAGCATCACGAGTCGCCAACTGTGCATATCGTGGTGGCCTCGCTGTTCGCCGCGATCATAGGGTCGATCTCGTTCTGGGGATCGATCATTGCGTTCGGTAAGTTGCAGGAGACAATCTCCGGATTCCCAATCGGTTTTGGCAAAGTCCAGCAGCCTATCAATTTGCTACTGTTGGTCGGCGCCATAGTCGCCGCAGTGGTCATCGGTCTGCACGCGCAGCCCGGATCCGCTGGGGCCTCGTTGTGGTGGATGATCGGGTTGCTGGTCGCCGCTGGCGTATTAGGCCTGATGGTGGTGCTGTCAATCGGCGGCGCCGACATGCCGGTGGTCATCTCCTTACTCAACGCTATGACTGGGCTCTCAGCTGCTGCGACGGGCCTGGCGCTGAACAATACCGCAATCATCGTGGCCGGCATGATCGTCGGCGCGTCCGGCTCGATCCTGACCAATCTCATGGCCAAGGCGATGAACCGCTCCATACCCGCGATCGTCGCAGGAGGTTTCGGTAGCGGTGGCGTGGCACCCAGCCGTGACGGTGACAAGCAAGTCAAATCCACCTCGGCAGCCGATGCGGCGATCCAGATGGCTTACGCCAACCAGGTGATCGTGGTGCCGGGCTACGGGCTGGCGGTCGCGCAGGCCCAGCACGTTGTCAAAGACATGGCGTCCTTGCTGGAGAACAAAGGTGTGCCGGTGAGTTACGCGATTCACCCGGTTGCTGGCCGGATGCCCGGACACATGAATGTGTTGCTGGCTGAAGCAGAGGTCGACTACGACGCCATGAAGGACATGGACGACATCAACGATGAGTTCGCTCGTACCGATGTTGTGATTGTCATCGGCGCCAACGACGTCACCAACCCGGCGGCCCGTAACGAGACAGCCAGCCCGATCTATGGGATGCCGATCCTGAATGTTGATAAAGCGAAGTCGGTTATAGTGCTTAAGAGGTCGATGAACTCCGGATTTGCGGGCATTGACAACCGGCTATTCTACGCCGACGGTACCACCATGTTGTTCGGTGATGCCAAACAGTCGGTGACTGAGGTCACTGAGGAACTGAAG

Protein Sequence 

>ML2634c_PntB_protein
GGQMNYFVIGLYILAFALFITGLMGLTGPRTAVSGNLIAAVGMTIAVAATLVKIRHTEQWVLIIAALVVGIVLGFPPARLTKVTAMPQLVAFFNGVGGGTVALIALSEFIETSGFSEFQHHESPTVHIVVASLFAAIIGSISFWGSIIAFGKLQETISGFPIGFGKVQQPINLLLLVGAIVAAVVIGLHAQPGSAGASLWWMIGLLVAAGVLGLMVVLSIGGADMPVVISLLNAMTGLSAAATGLALNNTAIIVAGMIVGASGSILTNLMAKAMNRSIPAIVAGGFGSGGVAPSRDGDKQVKSTSAADAAIQMAYANQVIVVPGYGLAVAQAQHVVKDMASLLENKGVPVSYAIHPVAGRMPGHMNVLLAEAEVDYDAMKDMDDINDEFARTDVVIVIGANDVTNPAARNETASPIYGMPILNVDKAKSVIVLKRSMNSGFAGIDNRLFYADGTTMLFGDAKQSVTEVTEELK

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PntB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

57 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PntB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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